STRINGSTRING
POLR2L-2 POLR2L-2 ELOC ELOC GTF2F1 GTF2F1 POLR2D POLR2D CCNH CCNH NCBP2L NCBP2L TCEANC TCEANC POLR2H POLR2H TCEANC2 TCEANC2 LOC100073305 LOC100073305 F7BQV6_HORSE F7BQV6_HORSE CTR9 CTR9 AFF4 AFF4 PRF1 PRF1 NELFE NELFE POLR2I POLR2I POLR2B POLR2B CDC73 CDC73 POLR2C POLR2C CCNT1 CCNT1 NCBP2 NCBP2 LOC100060825 LOC100060825 SUPT4H1 SUPT4H1 NELFCD NELFCD C20H6orf15 C20H6orf15 ELOA ELOA CCNK CCNK POLR2A POLR2A TCEA2 TCEA2 POLR2K POLR2K POLR2G POLR2G CTDP1 CTDP1 SUPT16H SUPT16H MNAT1 MNAT1 EAF1 EAF1 SLC39A13 SLC39A13 CCNQ CCNQ NCBP1 NCBP1 GTF2F2 GTF2F2 ERCC3 ERCC3 ENSECAP00000028527 ENSECAP00000028527 GTF2H4 GTF2H4 ERCC2 ERCC2 TCEA3 TCEA3 TCEA1 TCEA1 ELL ELL NELFB NELFB ELOB ELOB CDK7 CDK7 SUPT5H SUPT5H MLLT3 MLLT3 CDK9 CDK9 SUPT6H SUPT6H LEO1 LEO1 GTF2H1 GTF2H1 POLR2E POLR2E NELFA NELFA ELOA-2 ELOA-2 MLLT1 MLLT1 AFF1 AFF1 PAF1 PAF1 GTF2H5 GTF2H5 CCNT2 CCNT2 POLR2J POLR2J RTF1 RTF1 POLR2L POLR2L ENSECAP00000046013 ENSECAP00000046013 EAF2 EAF2 WDR61 WDR61 CINP CINP IWS1 IWS1 GTF2H3 GTF2H3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2L-2RNA polymerase II subunit L. (79 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (557 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (150 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (381 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain containing 2. (208 aa)
LOC100073305General transcription factor IIH subunit. (395 aa)
F7BQV6_HORSEUncharacterized protein. (763 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
AFF4AF4/FMR2 family member 4. (1164 aa)
PRF1Perforin 1. (555 aa)
NELFENegative elongation factor complex member E. (442 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
CDC73Cell division cycle 73. (531 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
CCNT1Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNAP II) (By similarity). In case of equine infectious anemia virus (EIAV) infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Ta [...] (751 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
LOC100060825Uncharacterized protein. (253 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
NELFCDNegative elongation factor complex member C/D. (597 aa)
C20H6orf15Chromosome 20 C6orf15 homolog. (312 aa)
ELOAUncharacterized protein. (774 aa)
CCNKCyclin K; Belongs to the cyclin family. (582 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
TCEA2Transcription elongation factor A2. (299 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (957 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
EAF1ELL associated factor 1. (357 aa)
SLC39A13Solute carrier family 39 member 13. (364 aa)
CCNQCyclin Q; Belongs to the cyclin family. (250 aa)
NCBP1Nuclear cap binding protein subunit 1. (793 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (261 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
ENSECAP00000028527Uncharacterized protein. (118 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (769 aa)
TCEA3Transcription elongation factor A3. (433 aa)
TCEA1Transcription elongation factor A1. (328 aa)
ELLElongation factor for RNA polymerase II. (729 aa)
NELFBNegative elongation factor complex member B. (627 aa)
ELOBElongin B. (118 aa)
CDK7Cyclin dependent kinase 7. (380 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
MLLT3MLLT3 super elongation complex subunit. (609 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (494 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1729 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (691 aa)
GTF2H1General transcription factor IIH subunit 1. (594 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
NELFANegative elongation factor complex member A. (546 aa)
ELOA-2Uncharacterized protein. (763 aa)
MLLT1MLLT1 super elongation complex subunit. (745 aa)
AFF1AF4/FMR2 family member 1. (1236 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (582 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (733 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (730 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
ENSECAP00000046013Uncharacterized protein. (79 aa)
EAF2ELL associated factor 2. (296 aa)
WDR61WD repeat domain 61. (317 aa)
CINPCyclin dependent kinase 2 interacting protein. (223 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (942 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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