STRINGSTRING
LOC100053403 LOC100053403 GTF2F1 GTF2F1 POLR2D POLR2D POLR2L-2 POLR2L-2 H2BC11 H2BC11 HIST2H3C HIST2H3C H4C15 H4C15 H2BC1 H2BC1 LOC100063835 LOC100063835 GTF2A1 GTF2A1 H2BC3 H2BC3 NRIP1 NRIP1 RUNX1 RUNX1 H2BC13 H2BC13 USF1 USF1 H2BC12 H2BC12 POLR2H POLR2H YY1 YY1 ZFP42 ZFP42 H2BU1 H2BU1 LOC100053259 LOC100053259 LOC102148494 LOC102148494 LOC100054193 LOC100054193 LOC100068321 LOC100068321 F7DCC3_HORSE F7DCC3_HORSE LOC111774036 LOC111774036 H2BC18 H2BC18 USF2 USF2 F6UIV7_HORSE F6UIV7_HORSE TBP TBP HSP90AB1 HSP90AB1 ZC3H12A ZC3H12A MED1 MED1 EBAG9 EBAG9 LOC100058496 LOC100058496 EP300 EP300 MYB MYB DDX5 DDX5 PGR PGR GTF2A2 GTF2A2 GTF2A1L GTF2A1L CHD1 CHD1 PTGES3 PTGES3 POLR2I POLR2I POLR2B POLR2B FOS FOS PRMT8 PRMT8 CBFB CBFB TFF3 TFF3 POLR2C POLR2C C7H11orf88 C7H11orf88 CCNT1 CCNT1 LOC100060825 LOC100060825 H2AZ2 H2AZ2 CXXC5 CXXC5 ENSECAP00000014555 ENSECAP00000014555 ZC3H12D ZC3H12D TRPS1 TRPS1 KANK3 KANK3 GREB1 GREB1 POLR2A POLR2A ZC3H12B ZC3H12B POLR2K POLR2K POLR2G POLR2G ESR1 ESR1 ERBB4 ERBB4 H2AZ1 H2AZ1 CREBBP CREBBP FOXA1 FOXA1 KDM4B KDM4B LOC100052511 LOC100052511 LOC100053259-2 LOC100053259-2 NCOA2 NCOA2 LOC100053018 LOC100053018 GATA3 GATA3 LOC100053259-3 LOC100053259-3 HSP90AA1 HSP90AA1 LOC100054462 LOC100054462 GTF2F2 GTF2F2 KAT5 KAT5 LOC100053695 LOC100053695 LOC100068222 LOC100068222 GREB1L GREB1L LOC100053259-4 LOC100053259-4 ENSECAP00000028527 ENSECAP00000028527 LOC100053259-5 LOC100053259-5 H2BW1 H2BW1 LOC100053259-6 LOC100053259-6 LOC100053499 LOC100053499 LOC100053065 LOC100053065 KANK2 KANK2 LOC100073295 LOC100073295 TBPL1 TBPL1 KAT2B KAT2B TNRC6B TNRC6B JUND JUND ZC3H12C ZC3H12C LOC106782239 LOC106782239 CDK9 CDK9 NCOA1 NCOA1 POLR2E POLR2E SP1 SP1 LOC100054332 LOC100054332 ENSECAP00000038853 ENSECAP00000038853 KANK4 KANK4 ENSECAP00000042780 ENSECAP00000042780 LOC106782250 LOC106782250 KANK1 KANK1 LOC102149092 LOC102149092 LOC100052568 LOC100052568 NCOA3 NCOA3 LOC100054473 LOC100054473 POLR2J POLR2J POLR2L POLR2L ENSECAP00000045686 ENSECAP00000045686 ENSECAP00000045922 ENSECAP00000045922 ENSECAP00000046013 ENSECAP00000046013 LOC100053968 LOC100053968 LOC100054521 LOC100054521 H2BC21 H2BC21 KDM1A KDM1A CARM1 CARM1 LOC100630823 LOC100630823 ZNF217 ZNF217 PRMT1 PRMT1 ENSECAP00000049664 ENSECAP00000049664 LOC111771646 LOC111771646 LOC111772365 LOC111772365 H2BW4 H2BW4 ENSECAP00000051701 ENSECAP00000051701 H2BC5 H2BC5 LOC100053847 LOC100053847 LOC111771533 LOC111771533 ENSECAP00000053350 ENSECAP00000053350 FOSB FOSB H2BC19 H2BC19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100053403Histone H4. (103 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (557 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
POLR2L-2RNA polymerase II subunit L. (79 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
HIST2H3CHistone H3; Belongs to the histone H3 family. (136 aa)
H4C15Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (106 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC100063835Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
NRIP1Nuclear receptor interacting protein 1. (1155 aa)
RUNX1RUNX family transcription factor 1. (537 aa)
H2BC13Histone H2B; Belongs to the histone H2B family. (198 aa)
USF1Upstream transcription factor 1. (314 aa)
H2BC12Histone H2B; Belongs to the histone H2B family. (187 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
YY1YY1 transcription factor. (748 aa)
ZFP42ZFP42 zinc finger protein. (186 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100053259Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102148494Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
LOC100054193Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100068321Histone H2B; Belongs to the histone H2B family. (126 aa)
F7DCC3_HORSEHistone H3; Belongs to the histone H3 family. (136 aa)
LOC111774036Histone H3; Belongs to the histone H3 family. (136 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (126 aa)
USF2Upstream transcription factor 2, c-fos interacting. (346 aa)
F6UIV7_HORSEUncharacterized protein. (300 aa)
TBPTATA-box binding protein. (329 aa)
HSP90AB1Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (730 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (615 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
EBAG9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (213 aa)
LOC100058496CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (463 aa)
EP300E1A binding protein p300. (2430 aa)
MYBMYB proto-oncogene, transcription factor. (757 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
PGRProgesterone receptor. (934 aa)
GTF2A2General transcription factor IIA subunit 2. (140 aa)
GTF2A1LUncharacterized protein. (473 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1713 aa)
PTGES3Prostaglandin E synthase 3. (160 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (381 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
CBFBCore-binding factor subunit beta. (188 aa)
TFF3Trefoil factor 3. (80 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
C7H11orf88Chromosome 7 C11orf88 homolog. (168 aa)
CCNT1Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNAP II) (By similarity). In case of equine infectious anemia virus (EIAV) infection, binds to the nuclear transcriptional activator Tat, increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Ta [...] (751 aa)
LOC100060825Uncharacterized protein. (253 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
CXXC5CXXC finger protein 5. (319 aa)
ENSECAP00000014555H3 histone family member 3B. (136 aa)
ZC3H12DZinc finger CCCH-type containing 12D. (542 aa)
TRPS1Transcriptional repressor GATA binding 1. (1294 aa)
KANK3KN motif and ankyrin repeat domains 3. (820 aa)
GREB1Growth regulating estrogen receptor binding 1. (1951 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
ZC3H12BZinc finger CCCH-type containing 12B. (837 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
ESR1Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (608 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
CREBBPCREB binding protein. (2442 aa)
FOXA1Forkhead box A1. (504 aa)
KDM4BLysine demethylase 4B. (1184 aa)
LOC100052511Histone H4. (103 aa)
LOC100053259-2Histone H3.1. (136 aa)
NCOA2Nuclear receptor coactivator. (1481 aa)
LOC100053018Histone H4. (103 aa)
GATA3GATA binding protein 3. (445 aa)
LOC100053259-3Histone H3.1. (136 aa)
HSP90AA1Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] (835 aa)
LOC100054462Histone domain-containing protein. (444 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (261 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
LOC100053695Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100068222Histone H2B; Belongs to the histone H2B family. (126 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1967 aa)
LOC100053259-4Histone H3.1. (136 aa)
ENSECAP00000028527Uncharacterized protein. (118 aa)
LOC100053259-5Histone H3.1. (136 aa)
H2BW1Histone domain-containing protein; Belongs to the histone H2B family. (168 aa)
LOC100053259-6Histone H3.1. (136 aa)
LOC100053499Histone H2B type 1. (126 aa)
LOC100053065Histone H3.1. (136 aa)
KANK2KN motif and ankyrin repeat domains 2. (947 aa)
LOC100073295Histone domain-containing protein; Belongs to the histone H2B family. (122 aa)
TBPL1TATA-box binding protein like 1. (217 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (824 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1872 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (349 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (1054 aa)
LOC106782239Histone H4. (103 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (494 aa)
NCOA1Nuclear receptor coactivator. (1442 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
SP1Sp1 transcription factor. (787 aa)
LOC100054332Histone H4. (99 aa)
ENSECAP00000038853annotation not available (168 aa)
KANK4KN motif and ankyrin repeat domains 4. (1011 aa)
ENSECAP00000042780annotation not available (103 aa)
LOC106782250Histone H4. (103 aa)
KANK1KN motif and ankyrin repeat domains 1. (1433 aa)
LOC102149092Histone H2A; Belongs to the histone H2A family. (115 aa)
LOC100052568Histone H2B; Belongs to the histone H2B family. (126 aa)
NCOA3Nuclear receptor coactivator. (1427 aa)
LOC100054473Histone H2B; Belongs to the histone H2B family. (126 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
ENSECAP00000045686annotation not available (168 aa)
ENSECAP00000045922annotation not available (103 aa)
ENSECAP00000046013Uncharacterized protein. (79 aa)
LOC100053968Histone H2B type 2-E. (126 aa)
LOC100054521Histone H4. (103 aa)
H2BC21Histone H2B type 2-E. (126 aa)
KDM1ALysine demethylase 1A. (1007 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (608 aa)
LOC100630823Histone H4. (103 aa)
ZNF217Zinc finger protein 217. (1051 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
ENSECAP00000049664annotation not available (136 aa)
LOC111771646Histone H2A-Bbd type 2/3-like. (115 aa)
LOC111772365Histone domain-containing protein; Belongs to the histone H2B family. (142 aa)
H2BW4Histone domain-containing protein; Belongs to the histone H2B family. (170 aa)
ENSECAP00000051701annotation not available (126 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100053847Histone H2B type 1. (126 aa)
LOC111771533Histone H2A-Bbd type 2/3-like. (115 aa)
ENSECAP00000053350annotation not available (136 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
H2BC19Histone H2B; Belongs to the histone H2B family. (145 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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