STRINGSTRING
PAOX PAOX C16H3orf18 C16H3orf18 HSCB HSCB HSDL2 HSDL2 UBC-2 UBC-2 DHRS2 DHRS2 ENSECAP00000034818 ENSECAP00000034818 UBL4B UBL4B ENSECAP00000034428 ENSECAP00000034428 TAZ TAZ LOC100146242 LOC100146242 CHCHD3 CHCHD3 ALDH3A2 ALDH3A2 AGPS AGPS CACUL1 CACUL1 LOC100070407 LOC100070407 PHYHD1 PHYHD1 DHRS4 DHRS4 PRNP PRNP TIMM44 TIMM44 VAPA VAPA FIS1 FIS1 UBE2D1 UBE2D1 ENSECAP00000028943 ENSECAP00000028943 CMC4 CMC4 COX17 COX17 GFER GFER DNAJC15 DNAJC15 PEX3 PEX3 DPY19L2 DPY19L2 EPHX3 EPHX3 UBE2D2 UBE2D2 SEC61B SEC61B ECH1 ECH1 PXMP4 PXMP4 NOS2 NOS2 TIMM22 TIMM22 PEX11G PEX11G OTC OTC ATP5F1B ATP5F1B MTX2 MTX2 PXMP2 PXMP2 COQ2 COQ2 SERP1 SERP1 MPP2 MPP2 CHCHD10 CHCHD10 ENSECAP00000041588 ENSECAP00000041588 PEX12 PEX12 PEX10 PEX10 CRAT CRAT SERP2 SERP2 ABCD3 ABCD3 SUGCT SUGCT DPY19L4 DPY19L4 ENSECAP00000044533 ENSECAP00000044533 UBE2D3 UBE2D3 MPP6 MPP6 ILVBL ILVBL GDAP1L1 GDAP1L1 ABCD1 ABCD1 LOC100069176 LOC100069176 C1QTNF12 C1QTNF12 KXD1 KXD1 VAMP2 VAMP2 ACBD5 ACBD5 ENSECAP00000049493 ENSECAP00000049493 PEX5L PEX5L LOC100055175 LOC100055175 NUDT8 NUDT8 CYB5A CYB5A PEX1 PEX1 GDAP1 GDAP1 TDRD12 TDRD12 CHCHD5 CHCHD5 LONP2 LONP2 TIMM8A TIMM8A PEX2 PEX2 APP APP COA4 COA4 MEST MEST TIMM17A TIMM17A LOC102149590 LOC102149590 MPV17 MPV17 MPV17L2 MPV17L2 UBA52 UBA52 CHCHD2 CHCHD2 UBE2D4 UBE2D4 PEX6 PEX6 ATP5MC1 ATP5MC1 PEX13 PEX13 FER1L6 FER1L6 MPV17L MPV17L FXN FXN NDUFAF3 NDUFAF3 RPS27A RPS27A HSD17B4 HSD17B4 ZFAND6 ZFAND6 LOC100056651 LOC100056651 PEX5 PEX5 TIMM9 TIMM9 TIMM21 TIMM21 TIMM23 TIMM23 NRDC NRDC DPY19L1 DPY19L1 PODN PODN UBE2J2 UBE2J2 EPHX4 EPHX4 LONP1 LONP1 TIMM8B TIMM8B BTBD8 BTBD8 PEX26 PEX26 BAG6 BAG6 EMD EMD UBL4A UBL4A PEX14 PEX14 SPIRE2 SPIRE2 GET4 GET4 PEX16 PEX16 CLDN15 CLDN15 TIMM13 TIMM13 LOC100069564 LOC100069564 LDHD LDHD CHCHD7 CHCHD7 SGTA SGTA TIMM10 TIMM10 NDUFB8 NDUFB8 TTC33 TTC33 GRPEL1 GRPEL1 GRPEL2 GRPEL2 ACOD1 ACOD1 SEC61G SEC61G NUDT7 NUDT7 DNAJC19 DNAJC19 HSPD1 HSPD1 TYSND1 TYSND1 SLC25A17 SLC25A17 ACAA1 ACAA1 STX5 STX5 USP9X USP9X GET1 GET1 PEX7 PEX7 GET3 GET3 COA6 COA6 OTOF OTOF SCP2D1 SCP2D1 SGTB SGTB UBC UBC PEX11B PEX11B TIMM50 TIMM50 CHCHD4 CHCHD4 CAMLG CAMLG HMOX1 HMOX1 CMC2 CMC2 TIMM10B TIMM10B PITRM1 PITRM1 ATAD1 ATAD1 DPY19L3 DPY19L3 FAM185A FAM185A BCS1L BCS1L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAOXPolyamine oxidase. (512 aa)
C16H3orf18Chromosome 16 C3orf18 homolog. (356 aa)
HSCBHscB mitochondrial iron-sulfur cluster cochaperone. (267 aa)
HSDL2Hydroxysteroid dehydrogenase like 2. (453 aa)
UBC-2Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (305 aa)
DHRS2Dehydrogenase/reductase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (362 aa)
ENSECAP00000034818Uncharacterized protein. (396 aa)
UBL4BUbiquitin-like domain-containing protein. (57 aa)
ENSECAP00000034428Uncharacterized protein. (97 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (291 aa)
LOC100146242ABC transmembrane type-1 domain-containing protein. (379 aa)
CHCHD3MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (310 aa)
ALDH3A2Aldehyde dehydrogenase 3 family member A2; Belongs to the aldehyde dehydrogenase family. (595 aa)
AGPSAlkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (689 aa)
CACUL1CDK2 associated cullin domain 1; Belongs to the cullin family. (457 aa)
LOC100070407ABC transporter domain-containing protein. (230 aa)
PHYHD1Uncharacterized protein. (295 aa)
DHRS4Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (402 aa)
PRNPMajor prion protein; Belongs to the prion family. (255 aa)
TIMM44Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (455 aa)
VAPAVAMP associated protein A. (317 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
UBE2D1UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ENSECAP00000028943Uncharacterized protein. (57 aa)
CMC4C-X9-C motif containing 4. (67 aa)
COX17Cytochrome c oxidase copper chaperone COX17. (63 aa)
GFERSulfhydryl oxidase. (379 aa)
DNAJC15J domain-containing protein. (233 aa)
PEX3Peroxisomal biogenesis factor 3. (377 aa)
DPY19L2Dpy-19 like 2. (772 aa)
EPHX3Epoxide hydrolase 3. (416 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
ECH1Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (328 aa)
PXMP4Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family. (212 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1247 aa)
TIMM22Translocase of inner mitochondrial membrane 22. (194 aa)
PEX11GPeroxisomal biogenesis factor 11 gamma. (240 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
MTX2Metaxin 2. (267 aa)
PXMP2Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (318 aa)
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (391 aa)
SERP1Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (66 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (678 aa)
CHCHD10CHCH domain-containing protein. (278 aa)
ENSECAP00000041588Uncharacterized protein. (152 aa)
PEX12Peroxisomal biogenesis factor 12. (396 aa)
PEX10Peroxisomal biogenesis factor 10. (383 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (782 aa)
SERP2Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (65 aa)
ABCD3ATP binding cassette subfamily D member 3. (664 aa)
SUGCTSuccinyl-CoA:glutarate-CoA transferase. (269 aa)
DPY19L4Dpy-19 like 4. (701 aa)
ENSECAP00000044533Ubiquitin-like domain-containing protein. (180 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
MPP6Membrane palmitoylated protein 6; Belongs to the MAGUK family. (583 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (631 aa)
GDAP1L1Ganglioside induced differentiation associated protein 1 like 1. (383 aa)
ABCD1ATP binding cassette subfamily D member 1. (732 aa)
LOC100069176Uncharacterized protein. (350 aa)
C1QTNF12C1q and TNF related 12. (300 aa)
KXD1KxDL motif containing 1. (194 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
ACBD5Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters. (532 aa)
ENSECAP00000049493Uncharacterized protein. (273 aa)
PEX5LPeroxisomal biogenesis factor 5 like. (626 aa)
LOC100055175Uncharacterized protein. (281 aa)
NUDT8Nudix hydrolase 8. (236 aa)
CYB5ACytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. (172 aa)
PEX1Peroxisomal biogenesis factor 1. (1370 aa)
GDAP1Ganglioside induced differentiation associated protein 1. (366 aa)
TDRD12Uncharacterized protein. (1749 aa)
CHCHD5Coiled-coil-helix-coiled-coil-helix domain containing 5. (153 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (868 aa)
TIMM8ATranslocase of inner mitochondrial membrane 8A; Belongs to the small Tim family. (97 aa)
PEX2Peroxisomal biogenesis factor 2. (305 aa)
APPAmyloid beta precursor protein. (811 aa)
COA4Cytochrome c oxidase assembly factor 4 homolog. (84 aa)
MESTMesoderm specific transcript. (335 aa)
TIMM17AMitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (171 aa)
LOC102149590Uncharacterized protein. (348 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa)
MPV17L2MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (203 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
CHCHD2Coiled-coil-helix-coiled-coil-helix domain containing 2. (155 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
PEX6Peroxisomal biogenesis factor 6. (981 aa)
ATP5MC1ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (136 aa)
PEX13Peroxisomal biogenesis factor 13. (403 aa)
FER1L6Fer-1 like family member 6. (1860 aa)
MPV17LUncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (196 aa)
FXNFrataxin. (211 aa)
NDUFAF3NADH:ubiquinone oxidoreductase complex assembly factor 3. (183 aa)
RPS27ARibosomal protein S27a. (156 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (850 aa)
ZFAND6Zinc finger AN1-type containing 6. (208 aa)
LOC100056651Uncharacterized protein. (338 aa)
PEX5Peroxisomal biogenesis factor 5. (661 aa)
TIMM9Translocase of inner mitochondrial membrane 9. (89 aa)
TIMM21Translocase of inner mitochondrial membrane 21. (247 aa)
TIMM23Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (209 aa)
NRDCNardilysin convertase. (1247 aa)
DPY19L1Dpy-19 like C-mannosyltransferase 1. (748 aa)
PODNPodocan. (617 aa)
UBE2J2Ubiquitin conjugating enzyme E2 J2. (259 aa)
EPHX4Epoxide hydrolase 4. (362 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (961 aa)
TIMM8BTranslocase of inner mitochondrial membrane 8 homolog B; Belongs to the small Tim family. (98 aa)
BTBD8BTB domain containing 8. (1803 aa)
PEX26Peroxisomal biogenesis factor 26. (320 aa)
BAG6BCL2 associated athanogene 6. (1073 aa)
EMDEmerin. (256 aa)
UBL4AUbiquitin like 4A. (159 aa)
PEX14Peroxisomal biogenesis factor 14. (374 aa)
SPIRE2Spire type actin nucleation factor 2. (719 aa)
GET4Golgi to ER traffic protein 4. (326 aa)
PEX16Peroxisomal membrane protein PEX16. (346 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (227 aa)
TIMM13Translocase of inner mitochondrial membrane 13; Belongs to the small Tim family. (95 aa)
LOC100069564Uncharacterized protein. (2001 aa)
LDHDLactate dehydrogenase D. (484 aa)
CHCHD7Coiled-coil-helix-coiled-coil-helix domain containing 7. (109 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)
TIMM10Translocase of inner mitochondrial membrane 10. (90 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
TTC33Tetratricopeptide repeat domain 33. (262 aa)
GRPEL1GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
GRPEL2GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (225 aa)
ACOD1Aconitate decarboxylase 1. (482 aa)
SEC61GSEC61 translocon gamma subunit. (68 aa)
NUDT7Nudix hydrolase 7. (259 aa)
DNAJC19DnaJ heat shock protein family (Hsp40) member C19. (116 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
TYSND1Serine protease; Belongs to the peptidase S1B family. (566 aa)
SLC25A17Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (355 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2570 aa)
GET1Guided entry of tail-anchored proteins factor 1. (174 aa)
PEX7Peroxisomal biogenesis factor 7. (319 aa)
GET3ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (348 aa)
COA6Cytochrome c oxidase assembly factor 6. (79 aa)
OTOFOtoferlin. (1996 aa)
SCP2D1SCP2 sterol binding domain containing 1. (151 aa)
SGTBSmall glutamine rich tetratricopeptide repeat containing beta. (304 aa)
UBCUbiquitin B. (305 aa)
PEX11BPeroxisomal biogenesis factor 11 beta. (259 aa)
TIMM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (355 aa)
CHCHD4Coiled-coil-helix-coiled-coil-helix domain containing 4. (140 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
HMOX1Heme oxygenase 1. (490 aa)
CMC2COX assembly mitochondrial protein. (79 aa)
TIMM10BMitochondrial import inner membrane translocase subunit Tim9 B-like protein. (105 aa)
PITRM1Pitrilysin metallopeptidase 1. (1035 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
DPY19L3Dpy-19 like C-mannosyltransferase 3. (716 aa)
FAM185AFamily with sequence similarity 185 member A. (435 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (22%) [HD]