STRINGSTRING
MPO MPO PTGS2 PTGS2 EPX EPX PXDN PXDN TPO TPO DUOX1 DUOX1 LPO LPO PXDNL PXDNL DUOX2 DUOX2 PTGS1 PTGS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MPOMyeloperoxidase. (724 aa)
PTGS2Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (666 aa)
EPXEosinophil peroxidase. (715 aa)
PXDNPeroxidasin. (1596 aa)
TPOThyroid peroxidase. (925 aa)
DUOX1Dual oxidase 1. (1551 aa)
LPOLactoperoxidase. (711 aa)
PXDNLPeroxidasin like. (1243 aa)
DUOX2Dual oxidase 2. (1545 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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