STRINGSTRING
LRRC31 LRRC31 TLR4 TLR4 LRRC42 LRRC42 TLR6 TLR6 TCTE1 TCTE1 LRRC23 LRRC23 LOC111771935 LOC111771935 CARMIL1 CARMIL1 LRRC14 LRRC14 LUM LUM LOC100146533 LOC100146533
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC31Leucine rich repeat containing 31. (562 aa)
TLR4Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (843 aa)
LRRC42Leucine rich repeat containing 42. (428 aa)
TLR6Toll-like receptor. (859 aa)
TCTE1T-complex-associated-testis-expressed 1. (647 aa)
LRRC23Leucine rich repeat containing 23. (345 aa)
LOC111771935Toll-like receptor 4. (843 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1432 aa)
LRRC14Leucine rich repeat containing 14. (493 aa)
LUMLumican. (341 aa)
LOC100146533Uncharacterized protein. (468 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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