STRINGSTRING
TRAF1 TRAF1 EIF4G2 EIF4G2 CALML3 CALML3 TRAF5 TRAF5 EIF4G1 EIF4G1 CALM1 CALM1 TRAF2 TRAF2 TRAF6 TRAF6 CALML4 CALML4 GAPDH GAPDH CCL2 CCL2 CDK5 CDK5 TRAF4 TRAF4 PRKACA PRKACA CALML5 CALML5 PRKACB PRKACB TRAF3 TRAF3 ZFP36 ZFP36 EIF4G3 EIF4G3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAF1TNF receptor-associated factor. (415 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (946 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1611 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (336 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa)
CALML4Calmodulin like 4. (197 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
CCL2C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (99 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
TRAF4TNF receptor-associated factor. (470 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (359 aa)
CALML5Calmodulin like 5. (149 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
ZFP36Uncharacterized protein. (662 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1774 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.