10 items (Equus caballus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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gene neighborhood

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textmining

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protein homology

Your Input:
	HCLS1	Hematopoietic cell-specific Lyn substrate 1. (498 aa)
	CTTN	Cortactin. (559 aa)
	PXDN	Peroxidasin. (1596 aa)
	PLEK	Pleckstrin. (362 aa)
	AFAP1L1	Actin filament associated protein 1 like 1. (802 aa)
	PLEK2	Pleckstrin 2. (362 aa)
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	PXDNL	Peroxidasin like. (1243 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (377 aa)
	AFAP1	Actin filament associated protein 1. (819 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	CTTN	ENSECAP00000013637	ENSECAP00000045577	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cortactin.	0.944
ACTB	HCLS1	ENSECAP00000013637	ENSECAP00000013412	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Hematopoietic cell-specific Lyn substrate 1.	0.946
ACTB	INS	ENSECAP00000013637	ENSECAP00000022114	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.906
ACTB	PLEK	ENSECAP00000013637	ENSECAP00000035289	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Pleckstrin.	0.466
ACTB	PLEK2	ENSECAP00000013637	ENSECAP00000025745	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Pleckstrin 2.	0.429
ACTB	PXDN	ENSECAP00000013637	ENSECAP00000040420	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Peroxidasin.	0.956
ACTB	PXDNL	ENSECAP00000013637	ENSECAP00000020314	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Peroxidasin like.	0.956
AFAP1	HCLS1	ENSECAP00000011844	ENSECAP00000013412	Actin filament associated protein 1.	Hematopoietic cell-specific Lyn substrate 1.	0.405
CTTN	ACTB	ENSECAP00000045577	ENSECAP00000013637	Cortactin.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.944
CTTN	HCLS1	ENSECAP00000045577	ENSECAP00000013412	Cortactin.	Hematopoietic cell-specific Lyn substrate 1.	0.922
CTTN	PXDN	ENSECAP00000045577	ENSECAP00000040420	Cortactin.	Peroxidasin.	0.415
CTTN	PXDNL	ENSECAP00000045577	ENSECAP00000020314	Cortactin.	Peroxidasin like.	0.415
HCLS1	ACTB	ENSECAP00000013412	ENSECAP00000013637	Hematopoietic cell-specific Lyn substrate 1.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.946
HCLS1	AFAP1	ENSECAP00000013412	ENSECAP00000011844	Hematopoietic cell-specific Lyn substrate 1.	Actin filament associated protein 1.	0.405
HCLS1	CTTN	ENSECAP00000013412	ENSECAP00000045577	Hematopoietic cell-specific Lyn substrate 1.	Cortactin.	0.922
HCLS1	PLEK	ENSECAP00000013412	ENSECAP00000035289	Hematopoietic cell-specific Lyn substrate 1.	Pleckstrin.	0.476
HCLS1	PXDN	ENSECAP00000013412	ENSECAP00000040420	Hematopoietic cell-specific Lyn substrate 1.	Peroxidasin.	0.430
HCLS1	PXDNL	ENSECAP00000013412	ENSECAP00000020314	Hematopoietic cell-specific Lyn substrate 1.	Peroxidasin like.	0.430
INS	ACTB	ENSECAP00000022114	ENSECAP00000013637	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.906
INS	PLEK	ENSECAP00000022114	ENSECAP00000035289	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Pleckstrin.	0.532