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ZBTB38 ZBTB38 PTCH1 PTCH1 IHH IHH DLEU7 DLEU7 TRIP11 TRIP11 NCAPG NCAPG CHCHD7 CHCHD7 EFEMP1 EFEMP1 PLAG1 PLAG1 CABLES1 CABLES1 JAZF1 JAZF1 ENTPD2 ENTPD2 GDF5 GDF5 MSTN MSTN PAPPA PAPPA DMRT1 DMRT1 HHIP HHIP PRKG2 PRKG2 SMAD2 SMAD2 IGF1 IGF1 DYM DYM LCORL LCORL LASP1 LASP1 LIN28B LIN28B HMGA2 HMGA2 DMRT2 DMRT2 SCMH1 SCMH1 SH3GL3 SH3GL3 CDK6 CDK6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZBTB38Zinc finger and BTB domain containing 38. (1196 aa)
PTCH1Patched 1. (1490 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
DLEU7Deleted in lymphocytic leukemia 7. (219 aa)
TRIP11Thyroid hormone receptor interactor 11. (1979 aa)
NCAPGNon-SMC condensin I complex subunit G. (1015 aa)
CHCHD7Coiled-coil-helix-coiled-coil-helix domain containing 7. (109 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (614 aa)
PLAG1PLAG1 zinc finger. (499 aa)
CABLES1Cdk5 and Abl enzyme substrate 1. (632 aa)
JAZF1JAZF zinc finger 1. (243 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa)
GDF5Growth differentiation factor 5. (499 aa)
MSTNGrowth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa)
PAPPAPappalysin 1. (1627 aa)
DMRT1DM domain-containing protein. (637 aa)
HHIPHedgehog interacting protein. (700 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
SMAD2Mothers against decapentaplegic homolog. (610 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa)
DYMDymeclin. (724 aa)
LCORLLigand dependent nuclear receptor corepressor like. (1871 aa)
LASP1LIM and SH3 protein 1. (323 aa)
LIN28BLin-28 homolog B. (258 aa)
HMGA2Uncharacterized protein. (156 aa)
DMRT2Doublesex and mab-3 related transcription factor 2. (556 aa)
SCMH1Scm polycomb group protein homolog 1. (663 aa)
SH3GL3ADAMTS like 3. (1703 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (403 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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