node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | AKT1 | ENSECAP00000013637 | ENSECAP00000033932 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.488 |
ACTB | AKT2 | ENSECAP00000013637 | ENSECAP00000006890 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Non-specific serine/threonine protein kinase. | 0.583 |
ACTB | AKT3 | ENSECAP00000013637 | ENSECAP00000017503 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.417 |
ACTB | AR | ENSECAP00000013637 | ENSECAP00000008070 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Androgen receptor. | 0.643 |
ACTB | EGF | ENSECAP00000013637 | ENSECAP00000009190 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.882 |
ACTB | GAPDH | ENSECAP00000013637 | ENSECAP00000019665 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.967 |
ACTB | INS | ENSECAP00000013637 | ENSECAP00000022114 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.906 |
ACTB | PIK3CA | ENSECAP00000013637 | ENSECAP00000013092 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.415 |
ACTB | PTEN | ENSECAP00000013637 | ENSECAP00000014788 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Phosphatase and tensin homolog. | 0.699 |
ACTB | PXDN | ENSECAP00000013637 | ENSECAP00000040420 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Peroxidasin. | 0.956 |
ACTB | PXDNL | ENSECAP00000013637 | ENSECAP00000020314 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Peroxidasin like. | 0.956 |
AKT1 | ACTB | ENSECAP00000033932 | ENSECAP00000013637 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.488 |
AKT1 | AKT2 | ENSECAP00000033932 | ENSECAP00000006890 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase. | 0.929 |
AKT1 | AKT3 | ENSECAP00000033932 | ENSECAP00000017503 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.902 |
AKT1 | EGF | ENSECAP00000033932 | ENSECAP00000009190 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.467 |
AKT1 | GAPDH | ENSECAP00000033932 | ENSECAP00000019665 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.462 |
AKT1 | INS | ENSECAP00000033932 | ENSECAP00000022114 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.639 |
AKT1 | PALLD | ENSECAP00000033932 | ENSECAP00000035135 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Palladin, cytoskeletal associated protein. | 0.408 |
AKT1 | PIK3CA | ENSECAP00000033932 | ENSECAP00000013092 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.973 |
AKT1 | PTEN | ENSECAP00000033932 | ENSECAP00000014788 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphatase and tensin homolog. | 0.762 |