(12 nodes) (2014) Genomic analysis establishes correlation between growth and laryngeal neuropathy in Thoroughbreds. network (Equus caballus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCAPG	Non-SMC condensin I complex subunit G. (1015 aa)
	MYO9B	Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2198 aa)
	FAM184B	Family with sequence similarity 184 member B. (1068 aa)
	MSTN	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa)
	LCORL	Ligand dependent nuclear receptor corepressor like. (1871 aa)
	ZFAT	Zinc finger and AT-hook domain containing. (1291 aa)
	LASP1	LIM and SH3 protein 1. (323 aa)
	HMGA2	Uncharacterized protein. (156 aa)
	LOC111771463	BRICHOS domain-containing protein. (313 aa)
	ITM2A	Integral membrane protein 2A. (313 aa)
	MAF	MAF bZIP transcription factor; Belongs to the bZIP family. (429 aa)
	LOC111767494	Integral membrane protein 2A. (263 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM184B	LCORL	ENSECAP00000011559	ENSECAP00000035754	Family with sequence similarity 184 member B.	Ligand dependent nuclear receptor corepressor like.	0.781
FAM184B	NCAPG	ENSECAP00000011559	ENSECAP00000005997	Family with sequence similarity 184 member B.	Non-SMC condensin I complex subunit G.	0.854
HMGA2	LASP1	ENSECAP00000039603	ENSECAP00000038866	Uncharacterized protein.	LIM and SH3 protein 1.	0.740
HMGA2	LCORL	ENSECAP00000039603	ENSECAP00000035754	Uncharacterized protein.	Ligand dependent nuclear receptor corepressor like.	0.828
HMGA2	NCAPG	ENSECAP00000039603	ENSECAP00000005997	Uncharacterized protein.	Non-SMC condensin I complex subunit G.	0.792
HMGA2	ZFAT	ENSECAP00000039603	ENSECAP00000036223	Uncharacterized protein.	Zinc finger and AT-hook domain containing.	0.793
LASP1	HMGA2	ENSECAP00000038866	ENSECAP00000039603	LIM and SH3 protein 1.	Uncharacterized protein.	0.740
LASP1	LCORL	ENSECAP00000038866	ENSECAP00000035754	LIM and SH3 protein 1.	Ligand dependent nuclear receptor corepressor like.	0.797
LASP1	NCAPG	ENSECAP00000038866	ENSECAP00000005997	LIM and SH3 protein 1.	Non-SMC condensin I complex subunit G.	0.792
LASP1	ZFAT	ENSECAP00000038866	ENSECAP00000036223	LIM and SH3 protein 1.	Zinc finger and AT-hook domain containing.	0.870
LCORL	FAM184B	ENSECAP00000035754	ENSECAP00000011559	Ligand dependent nuclear receptor corepressor like.	Family with sequence similarity 184 member B.	0.781
LCORL	HMGA2	ENSECAP00000035754	ENSECAP00000039603	Ligand dependent nuclear receptor corepressor like.	Uncharacterized protein.	0.828
LCORL	LASP1	ENSECAP00000035754	ENSECAP00000038866	Ligand dependent nuclear receptor corepressor like.	LIM and SH3 protein 1.	0.797
LCORL	MSTN	ENSECAP00000035754	ENSECAP00000018852	Ligand dependent nuclear receptor corepressor like.	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	0.644
LCORL	NCAPG	ENSECAP00000035754	ENSECAP00000005997	Ligand dependent nuclear receptor corepressor like.	Non-SMC condensin I complex subunit G.	0.957
LCORL	ZFAT	ENSECAP00000035754	ENSECAP00000036223	Ligand dependent nuclear receptor corepressor like.	Zinc finger and AT-hook domain containing.	0.891
MSTN	LCORL	ENSECAP00000018852	ENSECAP00000035754	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	Ligand dependent nuclear receptor corepressor like.	0.644
MSTN	NCAPG	ENSECAP00000018852	ENSECAP00000005997	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	Non-SMC condensin I complex subunit G.	0.511
MSTN	ZFAT	ENSECAP00000018852	ENSECAP00000036223	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	Zinc finger and AT-hook domain containing.	0.480
NCAPG	FAM184B	ENSECAP00000005997	ENSECAP00000011559	Non-SMC condensin I complex subunit G.	Family with sequence similarity 184 member B.	0.854