STRINGSTRING
CASP8 CASP8 EGF EGF PGR PGR MMP9 MMP9 ACE ACE BAX BAX GAPDH GAPDH CASP3 CASP3 INS INS BCL2 BCL2 CASP9 CASP9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CASP8Caspase 8; Belongs to the peptidase C14A family. (464 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1209 aa)
PGRProgesterone receptor. (934 aa)
MMP9Matrix metallopeptidase 9. (714 aa)
ACEAngiotensin-converting enzyme. (1313 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
CASP3Caspase-3-like protein; Belongs to the peptidase C14A family. (277 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
BCL2BCL2 apoptosis regulator. (285 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (632 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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