STRINGSTRING
PKN2 PKN2 LCORL LCORL SCMH1 SCMH1 SDR16C5 SDR16C5 CYP19A1 CYP19A1 PTCH1 PTCH1 CAMLG CAMLG NCAPG NCAPG MAP3K3 MAP3K3 CHCHD7 CHCHD7 PLAG1 PLAG1 RPS20 RPS20 PITX1 PITX1 CATSPER3 CATSPER3 TXNDC15 TXNDC15 DDX46 DDX46 POLR2A POLR2A GDF5 GDF5 PENK PENK SPAG17 SPAG17 ATF7 ATF7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKN2Protein kinase N2. (983 aa)
LCORLLigand dependent nuclear receptor corepressor like. (1871 aa)
SCMH1Scm polycomb group protein homolog 1. (663 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (364 aa)
CYP19A1Aromatase; A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrogens, estrone and estradiol, respectively. Catalyzes three successive oxidations of C19 androgens: two conventional oxidations at C19 yielding 19-hydroxy and 19-oxo/19- aldehyde derivatives, followed by a third oxidative aromatization step that involves C1-beta hydrogen abstraction combined with cleavage of the C10-C19 bond to yield a phenolic A ring and formic acid. Alternatively, the third oxidative reaction yields a 19 [...] (586 aa)
PTCH1Patched 1. (1490 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
NCAPGNon-SMC condensin I complex subunit G. (1015 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
CHCHD7Coiled-coil-helix-coiled-coil-helix domain containing 7. (109 aa)
PLAG1PLAG1 zinc finger. (499 aa)
RPS20Ribosomal protein S20. (142 aa)
PITX1Homeobox protein. (314 aa)
CATSPER3Cation channel sperm associated 3. (400 aa)
TXNDC15Thioredoxin domain containing 15. (477 aa)
DDX46DEAD-box helicase 46. (1032 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
GDF5Growth differentiation factor 5. (499 aa)
PENKProenkephalin. (266 aa)
SPAG17Sperm associated antigen 17. (2226 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (494 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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