STRINGSTRING
PXDNL PXDNL ITGB1 ITGB1 TPM2 TPM2 PXN PXN PXDN PXDN RHOA RHOA TPM3 TPM3 CDC42 CDC42 INS INS AXL AXL VCL VCL EGF EGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PXDNLPeroxidasin like. (1243 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (808 aa)
TPM2Tropomyosin 2; Belongs to the tropomyosin family. (284 aa)
PXNPaxillin. (1236 aa)
PXDNPeroxidasin. (1596 aa)
RHOATransforming protein RhoA-like protein. (193 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (285 aa)
CDC42Cell division control protein 42-like protein. (191 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
VCLVinculin. (1284 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1209 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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