(7 nodes) (2017) A genome-wide association study for body weight in Japanese Thoroughbred racehorses clarifies candidate regions on chromosomes 3, 9, 15, and 18. network (Equus caballus)

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Your Input:
	MSTN	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa)
	TRIB2	Tribbles pseudokinase 2. (343 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	HMGA2	Uncharacterized protein. (156 aa)
	ZFAT	Zinc finger and AT-hook domain containing. (1291 aa)
	LCORL	Ligand dependent nuclear receptor corepressor like. (1871 aa)
	IGF1	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HMGA2	LCORL	ENSECAP00000039603	ENSECAP00000035754	Uncharacterized protein.	Ligand dependent nuclear receptor corepressor like.	0.828
HMGA2	ZFAT	ENSECAP00000039603	ENSECAP00000036223	Uncharacterized protein.	Zinc finger and AT-hook domain containing.	0.793
IGF1	MSTN	ENSECAP00000033255	ENSECAP00000018852	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	0.772
IGF1	TGFB2	ENSECAP00000033255	ENSECAP00000051244	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Transforming growth factor beta; Belongs to the TGF-beta family.	0.614
LCORL	HMGA2	ENSECAP00000035754	ENSECAP00000039603	Ligand dependent nuclear receptor corepressor like.	Uncharacterized protein.	0.828
LCORL	MSTN	ENSECAP00000035754	ENSECAP00000018852	Ligand dependent nuclear receptor corepressor like.	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	0.644
LCORL	ZFAT	ENSECAP00000035754	ENSECAP00000036223	Ligand dependent nuclear receptor corepressor like.	Zinc finger and AT-hook domain containing.	0.891
MSTN	IGF1	ENSECAP00000018852	ENSECAP00000033255	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.772
MSTN	LCORL	ENSECAP00000018852	ENSECAP00000035754	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	Ligand dependent nuclear receptor corepressor like.	0.644
MSTN	ZFAT	ENSECAP00000018852	ENSECAP00000036223	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	Zinc finger and AT-hook domain containing.	0.480
TGFB2	IGF1	ENSECAP00000051244	ENSECAP00000033255	Transforming growth factor beta; Belongs to the TGF-beta family.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.614
TRIB2	ZFAT	ENSECAP00000008343	ENSECAP00000036223	Tribbles pseudokinase 2.	Zinc finger and AT-hook domain containing.	0.408
ZFAT	HMGA2	ENSECAP00000036223	ENSECAP00000039603	Zinc finger and AT-hook domain containing.	Uncharacterized protein.	0.793
ZFAT	LCORL	ENSECAP00000036223	ENSECAP00000035754	Zinc finger and AT-hook domain containing.	Ligand dependent nuclear receptor corepressor like.	0.891
ZFAT	MSTN	ENSECAP00000036223	ENSECAP00000018852	Zinc finger and AT-hook domain containing.	Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.	0.480
ZFAT	TRIB2	ENSECAP00000036223	ENSECAP00000008343	Zinc finger and AT-hook domain containing.	Tribbles pseudokinase 2.	0.408