(6 nodes) (2018) Sensory neuronal P2RX4 receptors controls BDNF signaling in inflammatory pain. network (Equus caballus)

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Your Input:
	P2RX2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (454 aa)
	P2RX1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
	TAC1	Substance P. (130 aa)
	BDNF	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (299 aa)
	TRPV1	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (838 aa)
	P2RX3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (416 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	TAC1	ENSECAP00000035766	ENSECAP00000002225	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Substance P.	0.628
BDNF	TRPV1	ENSECAP00000035766	ENSECAP00000028605	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.757
P2RX1	P2RX2	ENSECAP00000008233	ENSECAP00000023841	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.708
P2RX1	P2RX3	ENSECAP00000008233	ENSECAP00000014688	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.968
P2RX2	P2RX1	ENSECAP00000023841	ENSECAP00000008233	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.708
P2RX2	P2RX3	ENSECAP00000023841	ENSECAP00000014688	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.773
P2RX3	P2RX1	ENSECAP00000014688	ENSECAP00000008233	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.968
P2RX3	P2RX2	ENSECAP00000014688	ENSECAP00000023841	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.773
P2RX3	TRPV1	ENSECAP00000014688	ENSECAP00000028605	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.478
TAC1	BDNF	ENSECAP00000002225	ENSECAP00000035766	Substance P.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.628
TAC1	TRPV1	ENSECAP00000002225	ENSECAP00000028605	Substance P.	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.891
TRPV1	BDNF	ENSECAP00000028605	ENSECAP00000035766	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.757
TRPV1	P2RX3	ENSECAP00000028605	ENSECAP00000014688	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.478
TRPV1	TAC1	ENSECAP00000028605	ENSECAP00000002225	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family.	Substance P.	0.891