STRINGSTRING
GAST GAST BRAF BRAF SP1 SP1 PXDN PXDN ALB ALB BTC BTC EPGN EPGN F6Y457_HORSE F6Y457_HORSE INS INS GAPDHS GAPDHS GAPDH GAPDH EREG EREG SRC SRC AREG AREG PXDNL PXDNL ARAF ARAF HBEGF HBEGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GASTBig gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. (107 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (793 aa)
SP1Sp1 transcription factor. (787 aa)
PXDNPeroxidasin. (1596 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (620 aa)
BTCBetacellulin. (188 aa)
EPGNEpithelial mitogen. (154 aa)
F6Y457_HORSEGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (396 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
EREGEpiregulin. (170 aa)
SRCTyrosine-protein kinase. (551 aa)
AREGAmphiregulin. (247 aa)
PXDNLPeroxidasin like. (1243 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (624 aa)
HBEGFHeparin binding EGF like growth factor. (390 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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