STRINGSTRING
ITGB6 ITGB6 ITGB2 ITGB2 ITGAV ITGAV PXDN PXDN PLEK PLEK SGCA SGCA ILK ILK PLEK2 PLEK2 ITGA2 ITGA2 CCL5 CCL5 PXDNL PXDNL ITGB8 ITGB8 ITGB3 ITGB3 ITGB7 ITGB7 SRC SRC ITGB4 ITGB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
ITGB2Integrin beta. (873 aa)
ITGAVFamily with sequence similarity 171 member B; Belongs to the integrin alpha chain family. (1787 aa)
PXDNPeroxidasin. (1596 aa)
PLEKPleckstrin. (362 aa)
SGCAIntegrin subunit alpha 3; Belongs to the integrin alpha chain family. (1075 aa)
ILKIntegrin linked kinase. (452 aa)
PLEK2Pleckstrin 2. (362 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1301 aa)
CCL5C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family. (91 aa)
PXDNLPeroxidasin like. (1243 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
SRCTyrosine-protein kinase. (551 aa)
ITGB4Integrin beta. (1805 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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