(10 nodes) (2019) Triterpenoids from Cyclocarya paliurus that Enhance Glucose Uptake in 3T3-L1 Adipocytes. network (Equus caballus)

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Your Input:
	PXDN	Peroxidasin. (1596 aa)
	IRS1	Insulin receptor substrate 1. (1239 aa)
	SLC2A4	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	CPED1	Cadherin like and PC-esterase domain containing 1. (1026 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	PXDNL	Peroxidasin like. (1243 aa)
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa)
	LOC100069009	Uncharacterized protein. (571 aa)
	ALB	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (620 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	GAPDH	ENSECAP00000041304	ENSECAP00000019665	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Glyceraldehyde-3-phosphate dehydrogenase.	0.965
ALB	GSK3B	ENSECAP00000041304	ENSECAP00000022500	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.644
ALB	INS	ENSECAP00000041304	ENSECAP00000022114	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.985
ALB	IRS1	ENSECAP00000041304	ENSECAP00000005422	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Insulin receptor substrate 1.	0.561
ALB	PXDN	ENSECAP00000041304	ENSECAP00000040420	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Peroxidasin.	0.985
ALB	PXDNL	ENSECAP00000041304	ENSECAP00000020314	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Peroxidasin like.	0.985
ALB	SLC2A4	ENSECAP00000041304	ENSECAP00000006413	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.670
GAPDH	ALB	ENSECAP00000019665	ENSECAP00000041304	Glyceraldehyde-3-phosphate dehydrogenase.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.965
GAPDH	GSK3B	ENSECAP00000019665	ENSECAP00000022500	Glyceraldehyde-3-phosphate dehydrogenase.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.688
GAPDH	INS	ENSECAP00000019665	ENSECAP00000022114	Glyceraldehyde-3-phosphate dehydrogenase.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.929
GAPDH	IRS1	ENSECAP00000019665	ENSECAP00000005422	Glyceraldehyde-3-phosphate dehydrogenase.	Insulin receptor substrate 1.	0.660
GAPDH	PXDN	ENSECAP00000019665	ENSECAP00000040420	Glyceraldehyde-3-phosphate dehydrogenase.	Peroxidasin.	0.974
GAPDH	PXDNL	ENSECAP00000019665	ENSECAP00000020314	Glyceraldehyde-3-phosphate dehydrogenase.	Peroxidasin like.	0.974
GAPDH	SLC2A4	ENSECAP00000019665	ENSECAP00000006413	Glyceraldehyde-3-phosphate dehydrogenase.	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.855
GSK3B	ALB	ENSECAP00000022500	ENSECAP00000041304	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.644
GSK3B	GAPDH	ENSECAP00000022500	ENSECAP00000019665	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.688
GSK3B	INS	ENSECAP00000022500	ENSECAP00000022114	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.795
GSK3B	IRS1	ENSECAP00000022500	ENSECAP00000005422	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Insulin receptor substrate 1.	0.502
GSK3B	LOC100069009	ENSECAP00000022500	ENSECAP00000038151	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.474
GSK3B	PXDN	ENSECAP00000022500	ENSECAP00000040420	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Peroxidasin.	0.637