10 items (Equus caballus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	PTEN	Phosphatase and tensin homolog. (576 aa)
	RHOA	Transforming protein RhoA-like protein. (193 aa)
	CDC42	Cell division control protein 42-like protein. (191 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
	NOX1	NADPH oxidase 1. (565 aa)
	PAK1	Non-specific serine/threonine protein kinase. (544 aa)
	VCL	Vinculin. (1284 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1209 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (294 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	EGF	ENSECAP00000025414	ENSECAP00000009190	Cell division control protein 42-like protein.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.748
CDC42	GAPDH	ENSECAP00000025414	ENSECAP00000019665	Cell division control protein 42-like protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.616
CDC42	NGF	ENSECAP00000025414	ENSECAP00000008419	Cell division control protein 42-like protein.	Nerve growth factor; Belongs to the NGF-beta family.	0.512
CDC42	PAK1	ENSECAP00000025414	ENSECAP00000016091	Cell division control protein 42-like protein.	Non-specific serine/threonine protein kinase.	0.999
CDC42	PTEN	ENSECAP00000025414	ENSECAP00000014788	Cell division control protein 42-like protein.	Phosphatase and tensin homolog.	0.950
CDC42	RHOA	ENSECAP00000025414	ENSECAP00000036784	Cell division control protein 42-like protein.	Transforming protein RhoA-like protein.	0.967
CDC42	ROCK1	ENSECAP00000025414	ENSECAP00000019271	Cell division control protein 42-like protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.802
CDC42	VCL	ENSECAP00000025414	ENSECAP00000011648	Cell division control protein 42-like protein.	Vinculin.	0.783
EGF	CDC42	ENSECAP00000009190	ENSECAP00000025414	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Cell division control protein 42-like protein.	0.748
EGF	GAPDH	ENSECAP00000009190	ENSECAP00000019665	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Glyceraldehyde-3-phosphate dehydrogenase.	0.890
EGF	NGF	ENSECAP00000009190	ENSECAP00000008419	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Nerve growth factor; Belongs to the NGF-beta family.	0.766
EGF	PTEN	ENSECAP00000009190	ENSECAP00000014788	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Phosphatase and tensin homolog.	0.765
EGF	RHOA	ENSECAP00000009190	ENSECAP00000036784	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Transforming protein RhoA-like protein.	0.718
EGF	ROCK1	ENSECAP00000009190	ENSECAP00000019271	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.412
EGF	VCL	ENSECAP00000009190	ENSECAP00000011648	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Vinculin.	0.648
GAPDH	CDC42	ENSECAP00000019665	ENSECAP00000025414	Glyceraldehyde-3-phosphate dehydrogenase.	Cell division control protein 42-like protein.	0.616
GAPDH	EGF	ENSECAP00000019665	ENSECAP00000009190	Glyceraldehyde-3-phosphate dehydrogenase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.890
GAPDH	NGF	ENSECAP00000019665	ENSECAP00000008419	Glyceraldehyde-3-phosphate dehydrogenase.	Nerve growth factor; Belongs to the NGF-beta family.	0.746
GAPDH	NOX1	ENSECAP00000019665	ENSECAP00000018182	Glyceraldehyde-3-phosphate dehydrogenase.	NADPH oxidase 1.	0.517
GAPDH	PTEN	ENSECAP00000019665	ENSECAP00000014788	Glyceraldehyde-3-phosphate dehydrogenase.	Phosphatase and tensin homolog.	0.793