C-C motif chemokine.

C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.

C-C motif chemokine.

C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.

C-C motif chemokine.

Chemokine receptor 5/2 large transcript; Belongs to the G-protein coupled receptor 1 family.

C-C motif chemokine.

C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.

C-C motif chemokine.

C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.

C-C motif chemokine.

CD4 molecule.

C-C motif chemokine.

Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).

C-C motif chemokine.

C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.

C-C motif chemokine.

C-X-C motif chemokine.

C-C motif chemokine.

G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.

C-C motif chemokine.

C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.

C-C motif chemokine.

Forkhead box P3.

C-C motif chemokine.

Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.

C-C motif chemokine.

Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...]

C-C motif chemokine.

Interleukin-13.

C-C motif chemokine.

Uncharacterized protein.

C-C motif chemokine.

Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.

C-C motif chemokine.

Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells.

C-C motif chemokine.

Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]

C-C motif chemokine.

Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.