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| | TRH | Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (245 aa) |
| | PRKAR1A | cAMP-dependent protein kinase type I-alph regulatory subunit-like protein. (378 aa) |
| | DENND4C | DENN domain containing 4C. (1993 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1128 aa) |
| | CDC42EP4 | CDC42 effector protein 4. (335 aa) |
| | RAB35 | RAB35, member RAS oncogene family. (201 aa) |
| | NUAK1 | NUAK family kinase 1. (667 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | KIF13A | Kinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (737 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (470 aa) |
| | CBL | Cbl proto-oncogene. (914 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | RABIF | RAB interacting factor. (123 aa) |
| | FARP2 | FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1057 aa) |
| | MAP4K4 | Mitogen-activated protein kinase kinase kinase kinase 4. (1318 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | NF1 | Neurofibromin 1. (3024 aa) |
| | ARF1 | ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | PPP1R9B | Protein phosphatase 1 regulatory subunit 9B. (821 aa) |
| | SLC1A1 | Amino acid transporter. (524 aa) |
| | PPP1R14A | Protein phosphatase 1 regulatory inhibitor subunit 14A. (147 aa) |
| | MYO9B | Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2198 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | EPS8L2 | EPS8 like 2. (716 aa) |
| | SLC1A5 | Amino acid transporter. (538 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (747 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa) |
| | RANBP10 | RAN binding protein 10. (671 aa) |
| | BTBD8 | BTB domain containing 8. (1803 aa) |
| | CNN1 | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (375 aa) |
| | PLD2 | Phospholipase. (933 aa) |
| | ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1454 aa) |
| | ARFGEF1 | ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa) |
| | ULK1 | Unc-51 like autophagy activating kinase 1. (1059 aa) |
| | PTEN | Phosphatase and tensin homolog. (576 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (680 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (544 aa) |
| | RIOK2 | RIO kinase 2. (573 aa) |
| | TBC1D10A | TBC1 domain family member 10A. (509 aa) |
| | PREX2 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1597 aa) |
| | SLC1A6 | Amino acid transporter. (564 aa) |
| | CNKSR1 | Connector enhancer of kinase suppressor of Ras 1. (722 aa) |
| | RADIL | Rap associating with DIL domain. (1068 aa) |
| | RRAGC | Ras related GTP binding C. (399 aa) |
| | CNN3 | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa) |
| | TRIO | Trio Rho guanine nucleotide exchange factor. (3107 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (700 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1591 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | MAP3K2 | Mitogen-activated protein kinase kinase kinase 2. (619 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa) |
| | TSC2 | TSC complex subunit 2. (1817 aa) |
| | ARFIP1 | ADP ribosylation factor interacting protein 1. (453 aa) |
| | SLC1A7 | Amino acid transporter. (560 aa) |
| | PXDNL | Peroxidasin like. (1243 aa) |
| | TBC1D10B | TBC1 domain family member 10B. (808 aa) |
| | DOCK6 | Dedicator of cytokinesis 6; Belongs to the DOCK family. (2082 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa) |
| | GAK | Cyclin G associated kinase. (1306 aa) |
| | ARFGEF2 | ADP ribosylation factor guanine nucleotide exchange factor 2. (1779 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | MAP3K9 | Mitogen-activated protein kinase kinase kinase 9. (1111 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1339 aa) |
| | SUMO1 | Small ubiquitin like modifier 1. (284 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | ITSN2 | Intersectin 2. (1689 aa) |
| | DACT3 | Dishevelled binding antagonist of beta catenin 3. (643 aa) |
| | DENND6A | DENN domain containing 6A. (608 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa) |
| | PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha. (400 aa) |
| | STK3 | Serine/threonine kinase 3. (574 aa) |
| | CDC42BPB | CDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1728 aa) |
| | AGFG1 | ArfGAP with FG repeats 1. (666 aa) |
| | DAB2IP | DAB2 interacting protein. (1166 aa) |
| | CNN2 | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (309 aa) |
| | BIN1 | Bridging integrator 1. (690 aa) |
| | RRAS | RAS related. (220 aa) |
| | DCX | Doublecortin. (421 aa) |
| | RANBP1 | RAN binding protein 1. (278 aa) |
| | ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1131 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa) |
| | SNRK | SNF related kinase. (860 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1206 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (345 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | MCF2L | MCF.2 cell line derived transforming sequence like. (1185 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (654 aa) |
| | TBC1D9B | TBC1 domain family member 9B. (1437 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (793 aa) |
| | SRPK1 | SRSF protein kinase 1. (734 aa) |
| | RAB11FIP5 | RAB11 family interacting protein 5. (1305 aa) |
| | RANBP3 | RAN binding protein 3. (635 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1236 aa) |
| | ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (1002 aa) |
| | AFDN | Afadin, adherens junction formation factor. (1884 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1672 aa) |
| | BRF2 | RAB11 family interacting protein 1. (1298 aa) |
| | GAB1 | GRB2 associated binding protein 1. (771 aa) |
| | TNIK | TRAF2 and NCK interacting kinase. (1390 aa) |
| | ARHGEF28 | Rho guanine nucleotide exchange factor 28. (2026 aa) |
| | ANAPC15 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (301 aa) |
| | RABGAP1 | RAB GTPase activating protein 1. (1069 aa) |
| | AKAP13 | A-kinase anchoring protein 13. (2905 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1195 aa) |
| | RREB1 | Ras responsive element binding protein 1. (1773 aa) |
| | DNM1 | Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa) |
| | RHOA | Transforming protein RhoA-like protein. (193 aa) |
| | RPS6KC1 | Ribosomal protein S6 kinase C1. (1067 aa) |
| | SIK3 | SIK family kinase 3. (1389 aa) |
| | BCR | BCR activator of RhoGEF and GTPase. (1325 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1332 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1362 aa) |
| | RAP1GAP | RAP1 GTPase activating protein. (747 aa) |
| | CDC42BPA | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1810 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1603 aa) |
| | KALRN | Kalirin RhoGEF kinase. (2987 aa) |
| | PXDN | Peroxidasin. (1596 aa) |
| | CDKL5 | Cyclin dependent kinase like 5. (1072 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35. (1553 aa) |
| | DENND1A | DENN domain containing 1A. (1070 aa) |
| | GAPVD1 | GTPase activating protein and VPS9 domains 1. (1487 aa) |
| | TAOK3 | TAO kinase 3. (914 aa) |
| | MARCKS | Myristoylated alanine rich protein kinase C substrate. (336 aa) |
| | SLC1A2 | Amino acid transporter. (646 aa) |
| | PXN | Paxillin. (1236 aa) |
| | SRPK2 | SRSF protein kinase 2. (740 aa) |
| | PLD1 | Phospholipase. (1189 aa) |
| | RABEP2 | Rabaptin, RAB GTPase binding effector protein 2. (569 aa) |
| | RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1465 aa) |
| | DYRK1B | Dual specificity tyrosine phosphorylation regulated kinase 1B. (647 aa) |
| | CTTN | Cortactin. (559 aa) |
| | PLAT | Plasminogen activator, tissue type. (615 aa) |
| | DOCK7 | Dedicator of cytokinesis 7; Belongs to the DOCK family. (2143 aa) |
| | ABL2 | Tyrosine-protein kinase. (1078 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2573 aa) |
| | RASSF5 | Ras association domain family member 5. (422 aa) |
| | SRGAP2 | Uncharacterized protein. (1089 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (615 aa) |
| | RAB3IP | Sec2p domain-containing protein. (460 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1273 aa) |
| | TNKS2 | Poly [ADP-ribose] polymerase. (1318 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1613 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (879 aa) |
| | MAP4K1 | Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (855 aa) |
| | VRK3 | VRK serine/threonine kinase 3. (403 aa) |
