Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARG1 | ARG2 | ENSECAP00000021081 | ENSECAP00000014452 | Arginase. | Arginase. | 0.910 |
| ARG1 | CCL2 | ENSECAP00000021081 | ENSECAP00000021376 | Arginase. | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] | 0.676 |
| ARG1 | CCL3 | ENSECAP00000021081 | ENSECAP00000047808 | Arginase. | SCY domain-containing protein. | 0.441 |
| ARG1 | CD4 | ENSECAP00000021081 | ENSECAP00000007248 | Arginase. | CD4 molecule. | 0.736 |
| ARG1 | CD80 | ENSECAP00000021081 | ENSECAP00000033208 | Arginase. | CD80 molecule. | 0.672 |
| ARG1 | CD86 | ENSECAP00000021081 | ENSECAP00000040346 | Arginase. | CD86 molecule. | 0.898 |
| ARG1 | CSF1R | ENSECAP00000021081 | ENSECAP00000002580 | Arginase. | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.444 |
| ARG1 | CTLA4 | ENSECAP00000021081 | ENSECAP00000002814 | Arginase. | Cytotoxic T-lymphocyte associated protein 4. | 0.456 |
| ARG1 | CXCL10 | ENSECAP00000021081 | ENSECAP00000011110 | Arginase. | C-X-C motif chemokine. | 0.599 |
| ARG1 | FOXP3 | ENSECAP00000021081 | ENSECAP00000035296 | Arginase. | Forkhead box P3. | 0.642 |
| ARG1 | IFNG | ENSECAP00000021081 | ENSECAP00000030547 | Arginase. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.817 |
| ARG1 | IL10 | ENSECAP00000021081 | ENSECAP00000007097 | Arginase. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.906 |
| ARG1 | IL1B | ENSECAP00000021081 | ENSECAP00000053627 | Arginase. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells. | 0.823 |
| ARG1 | IL2 | ENSECAP00000021081 | ENSECAP00000013353 | Arginase. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.487 |
| ARG1 | IL6 | ENSECAP00000021081 | ENSECAP00000014219 | Arginase. | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | 0.927 |
| ARG1 | MMP9 | ENSECAP00000021081 | ENSECAP00000011232 | Arginase. | Matrix metallopeptidase 9. | 0.541 |
| ARG1 | TNF | ENSECAP00000021081 | ENSECAP00000001460 | Arginase. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.727 |
| ARG2 | ARG1 | ENSECAP00000014452 | ENSECAP00000021081 | Arginase. | Arginase. | 0.910 |
| ARG2 | CCL2 | ENSECAP00000014452 | ENSECAP00000021376 | Arginase. | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] | 0.437 |
| ARG2 | CD4 | ENSECAP00000014452 | ENSECAP00000007248 | Arginase. | CD4 molecule. | 0.598 |
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