STRINGSTRING
LRRC58 LRRC58 LRFN4 LRFN4 FBXL14 FBXL14 LGI1 LGI1 CARMIL1 CARMIL1 LRRC49 LRRC49 LRRC24 LRRC24 LRRK1 LRRK1 RANGAP1 RANGAP1 NLRP5 NLRP5 NLRP13 NLRP13 LRRC52 LRRC52 CNTRL CNTRL IGSF10 IGSF10 CHAD CHAD PXDNL PXDNL LRRC47 LRRC47 LRRC4C LRRC4C LRRC63 LRRC63 LRRC39 LRRC39 LGI4 LGI4 TLR10 TLR10 NLRP4 NLRP4 LRRN4 LRRN4 LRIG3 LRIG3 SLITRK2 SLITRK2 DCN DCN LGI3 LGI3 NLRP2 NLRP2 LRRC32 LRRC32 AMIGO2 AMIGO2 LRRC2 LRRC2 ECM2 ECM2 LRRC57 LRRC57 CNOT6 CNOT6 NLRX1 NLRX1 DRC3 DRC3 LRIG2 LRIG2 FBXL19 FBXL19 LOC100058594 LOC100058594 LRRC26 LRRC26 LRSAM1 LRSAM1 LUM LUM OPTC OPTC LRRC59 LRRC59 PRELP PRELP TLR2 TLR2 OGN OGN NLRP12 NLRP12 FLII FLII STK11IP STK11IP MXRA5 MXRA5 NOD2 NOD2 LRRC40 LRRC40 ELFN1 ELFN1 TLR7 TLR7 RNH1 RNH1 LOC102148739 LOC102148739 FLRT1 FLRT1 CEP78 CEP78 LRRC10 LRRC10 TLR1 TLR1 TRIL TRIL LINGO3 LINGO3 LRCH4 LRCH4 PODNL1 PODNL1 LRRC69 LRRC69 NLRP6 NLRP6 NLRP14 NLRP14 KERA KERA SLITRK4 SLITRK4 LRFN3 LRFN3 FMOD FMOD KDM2B KDM2B ISLR2 ISLR2 TLR3 TLR3 PIDD1 PIDD1 SLITRK5 SLITRK5 KDM2A KDM2A LRRC1 LRRC1 LOC111771935 LOC111771935 FBXL2 FBXL2 TCTE1 TCTE1 EPYC EPYC ENSECAP00000036381 ENSECAP00000036381 LRRC34 LRRC34 GP1BA GP1BA LRRC66 LRRC66 IGFALS IGFALS LRWD1 LRWD1 LRIT3 LRIT3 TLR5 TLR5 LRCH3 LRCH3 PXDN PXDN LRFN2 LRFN2 FBXL5 FBXL5 ENSECAP00000041329 ENSECAP00000041329 BGN BGN CNOT6L CNOT6L AMN1 AMN1 FBXL17 FBXL17 LRG1 LRG1 SLIT2 SLIT2 NOD1 NOD1 LRFN5 LRFN5 MFHAS1 MFHAS1 NLRC5 NLRC5 RTN4RL2 RTN4RL2 ENSECAP00000045503 ENSECAP00000045503 NYX NYX LRRC71 LRRC71 LRIG1 LRIG1 LRRC28 LRRC28 LRCH1 LRCH1 AP1G1 AP1G1 LRRC3B LRRC3B CHADL CHADL LINGO2 LINGO2 FBXL20 FBXL20 ADGRA3 ADGRA3 FBXL7 FBXL7 LRRTM4 LRRTM4 SCRIB SCRIB LRIT2 LRIT2 LRCH2 LRCH2 LRRC45 LRRC45 CIITA CIITA LRRC10B LRRC10B CD180 CD180 PPP1R7 PPP1R7 RSU1 RSU1 PHLPP1 PHLPP1 LOC100054965 LOC100054965 OMG OMG LRRC19 LRRC19 LRTM2 LRTM2 FBXL22 FBXL22 PODN PODN LRRC73 LRRC73 LRRC9 LRRC9 LRRC55 LRRC55 NLRC3 NLRC3 NLRP3 NLRP3 LRRN3 LRRN3 FBXL4 FBXL4 LRRCC1 LRRCC1 RXFP2 RXFP2 LRRC4B LRRC4B LRRD1 LRRD1 TONSL TONSL OMD OMD TLR9 TLR9 RXFP1 RXFP1 LRRC53 LRRC53 LGR4 LGR4 LRRC8A LRRC8A SLITRK6 SLITRK6 SKP2 SKP2 SLIT1 SLIT1 PPP1R37 PPP1R37 SHOC2 SHOC2 LINGO4 LINGO4 LRRC31 LRRC31 LGR6 LGR6 FBXL16 FBXL16 LGR5 LGR5 LRR1 LRR1 LRRC8C LRRC8C LRTM1 LRTM1 LRRK2 LRRK2 CARMIL2 CARMIL2 LOC100072794 LOC100072794 LRRIQ4 LRRIQ4 TLR4 TLR4 FBXL6 FBXL6 LRRC17 LRRC17 LRRC38 LRRC38 TLR8 TLR8 FLRT2 FLRT2 LRRTM1 LRRTM1 NLRP1 NLRP1 LRFN1 LRFN1 XRRA1 XRRA1 NISCH NISCH LRRC74A LRRC74A ASPN ASPN FBXL13 FBXL13 LRRTM2 LRRTM2 LRRC7 LRRC7 ELFN2 ELFN2 SLIT3 SLIT3 LOC100072493 LOC100072493 LRRC8D LRRC8D ERBIN ERBIN TSKU TSKU LRRN2 LRRN2 LINGO1 LINGO1 LOC100069988 LOC100069988 LRRC3 LRRC3 AMIGO3 AMIGO3 LRRC15 LRRC15 CPN2 CPN2 RTN4R RTN4R RTN4RL1 RTN4RL1 VASN VASN LRRC18 LRRC18 ISLR ISLR LRIT1 LRIT1 AMIGO1 AMIGO1 GP5 GP5 LRRC4 LRRC4 LRRN1 LRRN1 LRRC30 LRRC30 SLITRK1 SLITRK1 LRRC3C LRRC3C FLRT3 FLRT3 LRRTM3 LRRTM3 TLR6 TLR6 LRRC27 LRRC27 FBXL15 FBXL15 NRROS NRROS LRRC8E LRRC8E SLITRK3 SLITRK3 ADGRA2 ADGRA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC58Leucine rich repeat containing 58. (371 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (636 aa)
FBXL14F-box and leucine rich repeat protein 14. (409 aa)
LGI1Leucine rich glioma inactivated 1. (641 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1432 aa)
LRRC49Leucine rich repeat containing 49. (753 aa)
LRRC24Leucine rich repeat containing 24. (610 aa)
LRRK1Leucine rich repeat kinase 1. (2014 aa)
RANGAP1Ran GTPase activating protein 1. (590 aa)
NLRP5NLR family pyrin domain containing 5. (1100 aa)
NLRP13NLR family pyrin domain containing 13. (992 aa)
LRRC52Leucine rich repeat containing 52. (315 aa)
CNTRLCentriolin. (2346 aa)
IGSF10Immunoglobulin superfamily member 10. (2611 aa)
CHADChondroadherin. (359 aa)
PXDNLPeroxidasin like. (1243 aa)
LRRC47Leucine rich repeat containing 47. (644 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
LRRC63Leucine rich repeat containing 63. (572 aa)
LRRC39Leucine rich repeat containing 39. (335 aa)
LGI4Leucine rich repeat LGI family member 4. (537 aa)
TLR10Toll like receptor 10; Belongs to the Toll-like receptor family. (811 aa)
NLRP4NLR family pyrin domain containing 4. (996 aa)
LRRN4Leucine rich repeat neuronal 4. (739 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1122 aa)
SLITRK2SLIT and NTRK like family member 2. (845 aa)
DCNDecorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (360 aa)
LGI3Leucine rich repeat LGI family member 3. (548 aa)
NLRP2NLR family pyrin domain containing 2. (1076 aa)
LRRC32Leucine rich repeat containing 32. (745 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
LRRC2Leucine rich repeat containing 2. (370 aa)
ECM2Extracellular matrix protein 2. (698 aa)
LRRC57Leucine rich repeat containing 57. (239 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (557 aa)
NLRX1NLR family member X1. (975 aa)
DRC3Dynein regulatory complex subunit 3. (523 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1023 aa)
FBXL19F-box and leucine rich repeat protein 19. (694 aa)
LOC100058594Uncharacterized protein. (629 aa)
LRRC26Leucine rich repeat containing 26. (329 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (727 aa)
LUMLumican. (341 aa)
OPTCOpticin. (336 aa)
LRRC59Uncharacterized protein. (306 aa)
PRELPProline and arginine rich end leucine rich repeat protein. (397 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa)
OGNOsteoglycin. (298 aa)
NLRP12NLR family pyrin domain containing 12. (1061 aa)
FLIIFLII actin remodeling protein. (1270 aa)
STK11IPSerine/threonine kinase 11 interacting protein. (1074 aa)
MXRA5Matrix remodeling associated 5. (2851 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1013 aa)
LRRC40Leucine rich repeat containing 40. (602 aa)
ELFN1Extracellular leucine rich repeat and fibronectin type III domain containing 1. (825 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1054 aa)
RNH1Ribonuclease/angiogenin inhibitor 1. (683 aa)
LOC102148739NACHT domain-containing protein. (1069 aa)
FLRT1Fibronectin leucine rich transmembrane protein 1. (674 aa)
CEP78Centrosomal protein 78. (750 aa)
LRRC10Uncharacterized protein. (283 aa)
TLR1Toll-like receptor. (756 aa)
TRILTLR4 interactor with leucine rich repeats. (810 aa)
LINGO3Leucine rich repeat and Ig domain containing 3. (592 aa)
LRCH4Leucine rich repeats and calponin homology domain containing 4. (744 aa)
PODNL1Podocan like 1. (574 aa)
LRRC69Uncharacterized protein. (363 aa)
NLRP6NLR family pyrin domain containing 6. (892 aa)
NLRP14NLR family pyrin domain containing 14. (1094 aa)
KERAKeratocan. (389 aa)
SLITRK4SLIT and NTRK like family member 4. (1013 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (628 aa)
FMODFibromodulin. (392 aa)
KDM2BLysine demethylase 2B. (1265 aa)
ISLR2Immunoglobulin superfamily containing leucine rich repeat 2. (763 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (979 aa)
PIDD1P53-induced death domain protein 1. (915 aa)
SLITRK5SLIT and NTRK like family member 5. (958 aa)
KDM2ALysine demethylase 2A. (1206 aa)
LRRC1Leucine rich repeat containing 1. (614 aa)
LOC111771935Toll-like receptor 4. (843 aa)
FBXL2F-box and leucine rich repeat protein 2. (503 aa)
TCTE1T-complex-associated-testis-expressed 1. (647 aa)
EPYCEpiphycan. (322 aa)
ENSECAP00000036381TIR domain-containing protein; Belongs to the Toll-like receptor family. (772 aa)
LRRC34Leucine rich repeat containing 34. (448 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (608 aa)
LRRC66Leucine rich repeat containing 66. (1060 aa)
IGFALSInsulin like growth factor binding protein acid labile subunit. (605 aa)
LRWD1Leucine rich repeats and WD repeat domain containing 1. (745 aa)
LRIT3Leucine rich repeat, Ig-like and transmembrane domains 3. (680 aa)
TLR5Toll like receptor 5; Belongs to the Toll-like receptor family. (867 aa)
LRCH3Leucine rich repeats and calponin homology domain containing 3. (799 aa)
PXDNPeroxidasin. (1596 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (817 aa)
FBXL5F-box and leucine rich repeat protein 5. (689 aa)
ENSECAP00000041329Uncharacterized protein. (361 aa)
BGNBiglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (460 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (562 aa)
AMN1Antagonist of mitotic exit network 1 homolog. (322 aa)
FBXL17F-box and leucine rich repeat protein 17. (702 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (993 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (775 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1046 aa)
NLRC5NLR family CARD domain containing 5. (1868 aa)
RTN4RL2Reticulon 4 receptor like 2. (420 aa)
ENSECAP00000045503Endo/exonuclease/phosphatase domain-containing protein. (538 aa)
NYXNyctalopin. (484 aa)
LRRC71Leucine rich repeat containing 71. (561 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1094 aa)
LRRC28Leucine rich repeat containing 28. (394 aa)
LRCH1Leucine rich repeats and calponin homology domain containing 1. (763 aa)
AP1G1PH domain and leucine rich repeat protein phosphatase 2. (2139 aa)
LRRC3BLeucine rich repeat containing 3B. (259 aa)
CHADLChondroadherin like. (766 aa)
LINGO2Uncharacterized protein. (606 aa)
FBXL20F-box and leucine rich repeat protein 20. (438 aa)
ADGRA3Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1313 aa)
FBXL7F-box and leucine rich repeat protein 7. (491 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (591 aa)
SCRIBScribble planar cell polarity protein. (1690 aa)
LRIT2Leucine rich repeat, Ig-like and transmembrane domains 2. (556 aa)
LRCH2Leucine rich repeats and calponin homology domain containing 2. (764 aa)
LRRC45Leucine rich repeat containing 45. (695 aa)
CIITAClass II major histocompatibility complex transactivator. (1206 aa)
LRRC10BLeucine rich repeat containing 10B. (292 aa)
CD180CD180 molecule. (661 aa)
PPP1R7Protein phosphatase 1 regulatory subunit 7. (360 aa)
RSU1Ras suppressor protein 1. (296 aa)
PHLPP1PH domain and leucine rich repeat protein phosphatase 1. (1689 aa)
LOC100054965NACHT domain-containing protein. (866 aa)
OMGOligodendrocyte myelin glycoprotein. (443 aa)
LRRC19Leucine rich repeat containing 19. (368 aa)
LRTM2Leucine rich repeats and transmembrane domains 2. (370 aa)
FBXL22F-box domain-containing protein. (226 aa)
PODNPodocan. (617 aa)
LRRC73Leucine rich repeat containing 73. (316 aa)
LRRC9Leucine rich repeat containing 9. (1523 aa)
LRRC55Leucine rich repeat containing 55. (318 aa)
NLRC3NLR family CARD domain containing 3. (1107 aa)
NLRP3NLR family pyrin domain containing 3. (1031 aa)
LRRN3Leucine rich repeat neuronal 3. (708 aa)
FBXL4F-box and leucine rich repeat protein 4. (621 aa)
LRRCC1Leucine rich repeat and coiled-coil centrosomal protein 1. (1028 aa)
RXFP2Relaxin family peptide receptor 2. (739 aa)
LRRC4BLeucine rich repeat containing 4B. (713 aa)
LRRD1Leucine rich repeats and death domain containing 1. (870 aa)
TONSLTonsoku like, DNA repair protein. (1369 aa)
OMDOsteomodulin. (418 aa)
TLR9Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1031 aa)
RXFP1Relaxin family peptide receptor 1. (785 aa)
LRRC53Leucine rich repeat containing 53. (1245 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (1108 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
SLITRK6SLIT and NTRK like family member 6. (869 aa)
SKP2S-phase kinase associated protein 2. (436 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
PPP1R37Protein phosphatase 1 regulatory subunit 37. (705 aa)
SHOC2SHOC2 leucine rich repeat scaffold protein. (582 aa)
LINGO4Leucine rich repeat and Ig domain containing 4. (666 aa)
LRRC31Leucine rich repeat containing 31. (562 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (965 aa)
FBXL16F-box and leucine rich repeat protein 16. (483 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
LRR1Leucine rich repeat protein 1. (413 aa)
LRRC8CLeucine rich repeat containing 8 VRAC subunit B. (803 aa)
LRTM1Leucine rich repeats and transmembrane domains 1. (339 aa)
LRRK2Leucine rich repeat kinase 2. (2528 aa)
CARMIL2Capping protein regulator and myosin 1 linker 2. (1405 aa)
LOC100072794Uncharacterized protein. (557 aa)
LRRIQ4Leucine rich repeats and IQ motif containing 4. (561 aa)
TLR4Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (843 aa)
FBXL6F-box and leucine rich repeat protein 6. (617 aa)
LRRC17Leucine rich repeat containing 17. (441 aa)
LRRC38Leucine rich repeat containing 38. (298 aa)
TLR8Toll-like receptor 8; Belongs to the Toll-like receptor family. (1038 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
NLRP1NLR family pyrin domain containing 1. (1448 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (770 aa)
XRRA1X-ray radiation resistance associated 1. (817 aa)
NISCHNischarin. (1519 aa)
LRRC74ALeucine rich repeat containing 74A. (488 aa)
ASPNAsporin. (370 aa)
FBXL13F-box and leucine rich repeat protein 13. (734 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
LRRC7Leucine rich repeat containing 7. (1575 aa)
ELFN2Extracellular leucine rich repeat and fibronectin type III domain containing 2. (818 aa)
SLIT3Slit guidance ligand 3. (1521 aa)
LOC100072493TIR domain-containing protein. (976 aa)
LRRC8DLeucine rich repeat containing 8 VRAC subunit D. (861 aa)
ERBINErbb2 interacting protein. (1461 aa)
TSKUTsukushi, small leucine rich proteoglycan. (551 aa)
LRRN2Leucine rich repeat neuronal 2. (712 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (620 aa)
LOC100069988TIR domain-containing protein. (949 aa)
LRRC3Leucine rich repeat containing 3. (257 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (510 aa)
LRRC15Leucine rich repeat containing 15. (618 aa)
CPN2Carboxypeptidase N subunit 2. (547 aa)
RTN4RReticulon 4 receptor. (473 aa)
RTN4RL1Reticulon 4 receptor like 1. (445 aa)
VASNVasorin. (752 aa)
LRRC18Leucine rich repeat containing 18. (261 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (428 aa)
LRIT1Leucine rich repeat, Ig-like and transmembrane domains 1. (621 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
GP5Glycoprotein V platelet. (511 aa)
LRRC4Leucine rich repeat containing 4. (652 aa)
LRRN1Leucine rich repeat neuronal 1. (716 aa)
LRRC30Leucine rich repeat containing 30. (301 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
LRRC3CLeucine rich repeat containing 3C. (254 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (610 aa)
LRRTM3Leucine rich repeat transmembrane neuronal 3. (581 aa)
TLR6Toll-like receptor. (859 aa)
LRRC27Leucine rich repeat containing 27. (521 aa)
FBXL15F-box and leucine rich repeat protein 15. (347 aa)
NRROSNegative regulator of reactive oxygen species. (692 aa)
LRRC8ELeucine rich repeat containing 8 VRAC subunit E. (793 aa)
SLITRK3SLIT and NTRK like family member 3. (976 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1338 aa)
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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