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| | KITLG | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (303 aa) |
| | DGKH | Diacylglycerol kinase. (1238 aa) |
| | AGTR1 | Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (390 aa) |
| | F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa) |
| | LOC100050675 | Uncharacterized protein. (250 aa) |
| | LPAR6 | Oleoyl-L-alpha-lysophosphatidic acid recepto-like protein; Belongs to the G-protein coupled receptor 1 family. (344 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | SHC1 | SHC adaptor protein 1. (584 aa) |
| | CXCR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | LOC100058291 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (405 aa) |
| | PLA2G4D | Phospholipase A2. (817 aa) |
| | RAPGEF3 | Rap guanine nucleotide exchange factor 3. (923 aa) |
| | SPHK2 | Sphingosine kinase 2. (654 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | FCER1A | High affinity immunoglobulin E receptor alpha subunit. (255 aa) |
| | GRM3 | Glutamate metabotropic receptor 3. (879 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (528 aa) |
| | LPAR2 | Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa) |
| | GRM2 | Glutamate metabotropic receptor 2. (872 aa) |
| | FCER1G | Fc fragment of IgE receptor Ig. (86 aa) |
| | ARF1 | ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | SHC2 | SHC adaptor protein 2. (579 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1382 aa) |
| | TSC1 | TSC complex subunit 1. (1232 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. (421 aa) |
| | ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa) |
| | PTGFR | Prostaglandin F2alpha receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | AGPAT2 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (461 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1209 aa) |
| | F2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa) |
| | DGKA | Diacylglycerol kinase. (806 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | KIT | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1084 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (422 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | RALB | RAS like proto-oncogene B. (206 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | PLD2 | Phospholipase. (933 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity). (101 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | DGKK | Diacylglycerol kinase. (1261 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (483 aa) |
| | AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5. (365 aa) |
| | GRM7 | Glutamate metabotropic receptor 7. (922 aa) |
| | LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa) |
| | GRM4 | Glutamate metabotropic receptor 4. (912 aa) |
| | RALA | RAS like proto-oncogene A. (227 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | GRM5 | Glutamate metabotropic receptor 5. (1193 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (368 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | DNM3 | Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (873 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | TSC2 | TSC complex subunit 2. (1817 aa) |
| | RALGDS | Uncharacterized protein. (916 aa) |
| | DGKQ | Diacylglycerol kinase. (931 aa) |
| | AVPR2 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa) |
| | DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa) |
| | GRM1 | Glutamate metabotropic receptor 1. (1200 aa) |
| | GRM6 | Glutamate metabotropic receptor 6. (878 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (606 aa) |
| | CYTH4 | Cytohesin 4. (420 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1124 aa) |
| | GRM8 | Glutamate metabotropic receptor 8. (908 aa) |
| | PIK3R2 | Uncharacterized protein. (479 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa) |
| | LOC100056032 | Ras-GEF domain-containing protein. (645 aa) |
| | DGKI | Diacylglycerol kinase. (1078 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (249 aa) |
| | ENSECAP00000024650 | Uncharacterized protein. (88 aa) |
| | LPAR5 | Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | RRAS | RAS related. (220 aa) |
| | ENSECAP00000026008 | Ig-like domain-containing protein. (182 aa) |
| | PDGFD | Platelet derived growth factor D. (566 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1206 aa) |
| | DGKD | Diacylglycerol kinase. (1308 aa) |
| | DGKZ | Diacylglycerol kinase. (1111 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa) |
| | PLPP3 | Phospholipid phosphatase 3. (312 aa) |
| | PLA2G4A | Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response. (749 aa) |
| | PIP5K1A | PIPK domain-containing protein. (565 aa) |
| | GNA12 | G protein subunit alpha 12. (455 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1236 aa) |
| | LOC100052122 | Uncharacterized protein. (461 aa) |
| | PLCG2 | Phosphoinositide phospholipase C. (1331 aa) |
| | PLA2G4E | Phospholipase A2. (864 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa) |
| | GAB1 | GRB2 associated binding protein 1. (771 aa) |
| | PIP5K1B | Phosphatidylinositol-4-phosphate 5-kinase type 1 beta. (548 aa) |
| | DGKG | Diacylglycerol kinase. (819 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1195 aa) |
| | CYTH2 | Cytohesin 2. (584 aa) |
| | CYTH1 | Cytohesin 1. (564 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa) |
| | GAB2 | GRB2 associated binding protein 2. (708 aa) |
| | LOC102149416 | Ras-GEF domain-containing protein. (622 aa) |
| | DNM1 | Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa) |
| | RHOA | Transforming protein RhoA-like protein. (193 aa) |
| | SYK | Tyrosine-protein kinase. (716 aa) |
| | AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4. (378 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa) |
| | DGKB | Diacylglycerol kinase. (795 aa) |
| | MRAS | Muscle RAS oncogene homolog. (208 aa) |
| | MS4A2 | Membrane spanning 4-domains A2. (240 aa) |
| | DGKE | Diacylglycerol kinase. (603 aa) |
| | PLPP2 | Phospholipid phosphatase 2. (305 aa) |
| | JMJD7 | Phospholipase A2. (849 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (569 aa) |
| | AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3. (376 aa) |
| | AGPAT1 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (334 aa) |
| | SPHK1 | Sphingosine kinase 1. (459 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | CYTH3 | Cytohesin 3. (410 aa) |
| | PLD1 | Phospholipase. (1189 aa) |
| | PIP5K1C | Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (663 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | ARF2 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | SHC3 | SHC adaptor protein 3. (591 aa) |
| | LOC102150685 | Ras-GEF domain-containing protein. (571 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (594 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 6. (890 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2573 aa) |
| | LOC106780978 | Ras-GEF domain-containing protein. (703 aa) |
| | LPAR4 | Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1273 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1613 aa) |
| | LOC102148588 | Ras-GEF domain-containing protein. (438 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
