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| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (253 aa) |
| | CAB39L | Calcium binding protein 39 like. (337 aa) |
| | SESN2 | Sestrin 2. (481 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (231 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (737 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa) |
| | RNF152 | Ring finger protein 152. (203 aa) |
| | RRAGB | Ras related GTP binding B. (374 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (495 aa) |
| | LPIN2 | Lipin 2. (922 aa) |
| | IRS1 | Insulin receptor substrate 1. (1239 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | PRR5 | Proline rich 5. (421 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (528 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1382 aa) |
| | TSC1 | TSC complex subunit 1. (1232 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (747 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (483 aa) |
| | JMJD8 | WD repeat domain 24. (1023 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | SKP2 | S-phase kinase associated protein 2. (436 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | ATP6V1E2 | ATPase H+ transporting V1 subunit E2. (226 aa) |
| | LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa) |
| | TTI1 | TELO2 interacting protein 1. (1092 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa) |
| | DEPDC5 | DEP domain containing 5. (1602 aa) |
| | CAB39 | Calcium binding protein 39. (373 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | RRAGD | Ras related GTP binding D. (397 aa) |
| | RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | ATP6V1B2 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa) |
| | TBC1D7 | TBC1 domain family member 7. (293 aa) |
| | PTEN | Phosphatase and tensin homolog. (576 aa) |
| | ATP6V1D | V-type proton ATPase subunit D-like protein. (247 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) |
| | TELO2 | Telomere maintenance 2. (821 aa) |
| | STRADB | STE20 related adaptor beta. (418 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | CASTOR2 | Uncharacterized protein. (329 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | RRAGC | Ras related GTP binding C. (399 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | EIF4E2 | Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (245 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (700 aa) |
| | DEPTOR | DEP domain containing MTOR interacting protein. (545 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (475 aa) |
| | MIOS | Meiosis regulator for oocyte development. (875 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | TSC2 | TSC complex subunit 2. (1817 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | NPRL2 | NPR2 like, GATOR1 complex subunit. (380 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (633 aa) |
| | ATP6V1B1 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa) |
| | AKT1S1 | AKT1 substrate 1. (276 aa) |
| | ATP6V1G3 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | STRADA | STE20 related adaptor alpha. (431 aa) |
| | EIF4B | Eukaryotic translation initiation factor 4B. (647 aa) |
| | CASTOR1 | Cytosolic arginine sensor for mTORC1 subunit 1. (329 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa) |
| | PIK3R2 | Uncharacterized protein. (479 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | WDR59 | WD repeat domain 59. (1009 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1384 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (780 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | CLIP1 | CAP-Gly domain containing linker protein 1. (1970 aa) |
| | LPIN1 | Lipin 1. (1012 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (829 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (577 aa) |
| | ATP6V1C1 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (793 aa) |
| | ULK2 | Unc-51 like autophagy activating kinase 2. (1059 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (770 aa) |
| | RRAGA | Ras related GTP binding A. (313 aa) |
| | SLC3A2 | Solute carrier family 3 member 2. (595 aa) |
| | LOC100052122 | Uncharacterized protein. (461 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa) |
| | SLC38A9 | Solute carrier family 38 member 9. (611 aa) |
| | LPIN3 | Lipin 3. (927 aa) |
| | ANAPC15 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (301 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (210 aa) |
| | FNIP1 | Folliculin interacting protein 1. (1170 aa) |
| | ATP6V1H | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa) |
| | FNIP2 | Folliculin interacting protein 2. (1178 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa) |
| | RHOA | Transforming protein RhoA-like protein. (193 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa) |
| | ATP6V1A | ATPase H+ transporting V1 subunit A. (618 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (325 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | GRB10 | Growth factor receptor bound protein 10. (594 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (585 aa) |
| | NPRL3 | NPR3 like, GATOR1 complex subunit. (664 aa) |
| | ATP6V1G1 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | ATP6V1F | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase. (526 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (594 aa) |
| | RPS6KA6 | Ribosomal protein S6 kinase. (763 aa) |
| | ATP6V1E1 | ATPase H+ transporting V1 subunit E1. (279 aa) |
| | ATP6V1G2 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa) |
| | LAMTOR2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (150 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2573 aa) |
| | EIF4E | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (236 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1613 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (475 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (758 aa) |
