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| | CLEC2B | C-type lectin domain family 2 member B. (184 aa) |
| | GABARAPL2 | Gamma-aminobutyric acid receptor-associate protein-like 2-like protein. (117 aa) |
| | CCR3 | C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (377 aa) |
| | CCR1 | C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa) |
| | IFND2 | Uncharacterized protein. (170 aa) |
| | UBC | Ubiquitin B. (305 aa) |
| | TICAM1 | Toll like receptor adaptor molecule 1. (698 aa) |
| | CCR4 | C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (434 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (464 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | IFNB1 | Interferon beta; Has antiviral, antibacterial and anticancer activities. (186 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (194 aa) |
| | LOC100053210 | Uncharacterized protein. (184 aa) |
| | CTNNB1 | Beta catenin 1. (781 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | GNG14 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (528 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | CALM1 | Uncharacterized protein; Belongs to the calmodulin family. (336 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (494 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (472 aa) |
| | VEGFA | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (448 aa) |
| | CSF2 | Granulocyte-macrophage colony-stimulating factor. (152 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | EP300 | E1A binding protein p300. (2430 aa) |
| | JAK2 | Tyrosine-protein kinase. (1131 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (561 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (932 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | SRC | Tyrosine-protein kinase. (551 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa) |
| | TRADD | TNFRSF1A associated via death domain. (312 aa) |
| | FAS | Fas cell surface death receptor. (365 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (381 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1757 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity). (101 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (1049 aa) |
| | F6UE14_HORSE | MHC_I-like_Ag-recog domain-containing protein. (212 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (86 aa) |
| | LOC111768755 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (144 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (231 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (666 aa) |
| | F6QMH0_HORSE | Ig-like domain-containing protein. (222 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (365 aa) |
| | BECN2 | Beclin 2. (459 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | IRF3 | Interferon regulatory factor 3. (426 aa) |
| | HCK | Tyrosine-protein kinase. (525 aa) |
| | BECN1 | Beclin 1. (448 aa) |
| | RPS27A | Ribosomal protein S27a. (156 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (915 aa) |
| | JAK1 | Tyrosine-protein kinase. (1141 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (419 aa) |
| | TYK2 | Tyrosine-protein kinase. (1262 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (212 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | CALML4 | Calmodulin like 4. (197 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (442 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | CASP3 | Caspase-3-like protein; Belongs to the peptidase C14A family. (277 aa) |
| | STAT2 | Signal transducer and activator of transcription. (847 aa) |
| | NFKBIA | NFKB inhibitor alpha. (543 aa) |
| | E2F1 | E2F transcription factor 1. (436 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | E2F2 | E2F transcription factor 2. (549 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (340 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | IRF9 | Interferon regulatory factor 9. (394 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4. (531 aa) |
| | PIK3R2 | Uncharacterized protein. (479 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (1067 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (249 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (669 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (822 aa) |
| | E2F3 | E2F transcription factor 3. (546 aa) |
| | ENSECAP00000025114 | Ig-like domain-containing protein; Belongs to the MHC class I family. (455 aa) |
| | IL6ST | Interleukin 6 signal transducer. (1023 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) |
| | IFN-ALPHA2 | Interferon alpha-2; Produced by macrophages, IFN-alpha have antiviral activities. (184 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (164 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | WDR92 | Protein phosphatase 3 regulatory subunit B, alpha. (496 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | EQMHCC1 | Ig-like domain-containing protein; Belongs to the MHC class I family. (445 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (770 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (540 aa) |
| | LOC100052122 | Uncharacterized protein. (461 aa) |
| | CALML5 | Calmodulin like 5. (149 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (341 aa) |
| | PLCG2 | Phosphoinositide phospholipase C. (1331 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (534 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (979 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1073 aa) |
| | STAT1 | Signal transducer and activator of transcription. (749 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (381 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (758 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (446 aa) |
| | RAC1 | Rac family small GTPase 1. (221 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (717 aa) |
| | UBC-2 | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (305 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | SYK | Tyrosine-protein kinase. (716 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | LOC100056182 | Uncharacterized protein; Belongs to the MHC class I family. (362 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (413 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (628 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (363 aa) |
| | ATG14 | Autophagy related 14. (510 aa) |
| | LOC100053110 | Interferon alpha-4; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (184 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (632 aa) |
| | RB1 | RB transcriptional corepressor 1. (965 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | CD86 | CD86 molecule. (335 aa) |
| | CXCL1 | C-X-C motif chemokine. (113 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (421 aa) |
| | LOC100054114 | Ig-like domain-containing protein; Belongs to the MHC class I family. (347 aa) |
| | LYN | Tyrosine-protein kinase. (533 aa) |
| | LOC100054254 | Ig-like domain-containing protein. (467 aa) |
| | LOC100629951 | Interferon alpha-1; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (184 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | GNB1 | G protein subunit beta 1. (360 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | ZFP36 | Uncharacterized protein. (662 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (403 aa) |
| | LOC100629885 | Uncharacterized protein. (167 aa) |
| | IFNAR2 | Uncharacterized protein. (530 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (594 aa) |
| | LOC100064612 | Uncharacterized protein. (171 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 6. (890 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (844 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2573 aa) |
| | LOC100050473 | Ig-like domain-containing protein; Belongs to the MHC class I family. (389 aa) |
| | LOC100147174 | Uncharacterized protein. (186 aa) |
| | LOC100060505 | Uncharacterized protein. (1662 aa) |
| | GNB5 | G protein subunit beta 5. (395 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (108 aa) |
| | MHCB3 | Ig-like domain-containing protein; Belongs to the MHC class I family. (433 aa) |
| | LOC100059994 | Uncharacterized protein; Belongs to the MHC class I family. (592 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2757 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (475 aa) |
