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LOC111768663 | Peptidase S1 domain-containing protein. (255 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (253 aa) | ||||
DQA-2 | Ig-like domain-containing protein; Belongs to the MHC class II family. (293 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (139 aa) | ||||
IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (249 aa) | ||||
PRF1 | Perforin 1. (555 aa) | ||||
DRA | MHC class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (254 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (329 aa) | ||||
FAS | Fas cell surface death receptor. (365 aa) | ||||
IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (149 aa) | ||||
F6UE14_HORSE | MHC_I-like_Ag-recog domain-containing protein. (212 aa) | ||||
FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (283 aa) | ||||
IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) | ||||
CD40 | Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). (280 aa) | ||||
HLA-DOB | MHC class II histocompatibility antigen, DO beta chain. (258 aa) | ||||
LOC100060996 | MHC class II antigen. (263 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (256 aa) | ||||
HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (262 aa) | ||||
DRB | Ig-like domain-containing protein. (275 aa) | ||||
ENSECAP00000025114 | Ig-like domain-containing protein; Belongs to the MHC class I family. (455 aa) | ||||
ENSECAP00000026008 | Ig-like domain-containing protein. (182 aa) | ||||
LOC111767719 | Ig-like domain-containing protein. (187 aa) | ||||
LOC111772100 | Ig-like domain-containing protein. (173 aa) | ||||
EQMHCC1 | Ig-like domain-containing protein; Belongs to the MHC class I family. (445 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) | ||||
CD80 | CD80 molecule. (305 aa) | ||||
DQB | Ig-like domain-containing protein. (309 aa) | ||||
LOC100056182 | Uncharacterized protein; Belongs to the MHC class I family. (362 aa) | ||||
DRB-2 | Ig-like domain-containing protein. (288 aa) | ||||
CD86 | CD86 molecule. (335 aa) | ||||
LOC100054114 | Ig-like domain-containing protein; Belongs to the MHC class I family. (347 aa) | ||||
LOC106783094 | Ig-like domain-containing protein. (229 aa) | ||||
CD28 | CD28 molecule. (228 aa) | ||||
LOC100049805 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (302 aa) | ||||
CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) | ||||
LOC100050473 | Ig-like domain-containing protein; Belongs to the MHC class I family. (389 aa) | ||||
LOC100055651 | Peptidase S1 domain-containing protein. (244 aa) | ||||
MHCB3 | Ig-like domain-containing protein; Belongs to the MHC class I family. (433 aa) | ||||
HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (314 aa) | ||||
LOC100059994 | Uncharacterized protein; Belongs to the MHC class I family. (592 aa) | ||||
LOC100050711 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa) | ||||
LOC111767413 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa) | ||||
DRB-3 | MHC class II antigen. (266 aa) |