node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MFFC18_20540 | glyA | GCA_001642875_03541 | GCA_001642875_03733 | Unannotated protein; Belongs to the GcvT family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.590 |
arnA | fmt | GCA_001642875_04672 | GCA_001642875_03727 | Unannotated protein. | Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.928 |
arnA | gcvT_1 | GCA_001642875_04672 | GCA_001642875_03369 | Unannotated protein. | Unannotated protein; Belongs to the GcvT family. | 0.907 |
arnA | gcvT_2 | GCA_001642875_04672 | GCA_001642875_00276 | Unannotated protein. | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.907 |
arnA | glyA | GCA_001642875_04672 | GCA_001642875_03733 | Unannotated protein. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.917 |
arnA | purN | GCA_001642875_04672 | GCA_001642875_04364 | Unannotated protein. | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.923 |
fmt | arnA | GCA_001642875_03727 | GCA_001642875_04672 | Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Unannotated protein. | 0.928 |
fmt | gcvT_1 | GCA_001642875_03727 | GCA_001642875_03369 | Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Unannotated protein; Belongs to the GcvT family. | 0.907 |
fmt | gcvT_2 | GCA_001642875_03727 | GCA_001642875_00276 | Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.907 |
fmt | glyA | GCA_001642875_03727 | GCA_001642875_03733 | Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.917 |
fmt | purN | GCA_001642875_03727 | GCA_001642875_04364 | Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.919 |
gcvT_1 | arnA | GCA_001642875_03369 | GCA_001642875_04672 | Unannotated protein; Belongs to the GcvT family. | Unannotated protein. | 0.907 |
gcvT_1 | fmt | GCA_001642875_03369 | GCA_001642875_03727 | Unannotated protein; Belongs to the GcvT family. | Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.907 |
gcvT_1 | gcvT_2 | GCA_001642875_03369 | GCA_001642875_00276 | Unannotated protein; Belongs to the GcvT family. | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.929 |
gcvT_1 | glyA | GCA_001642875_03369 | GCA_001642875_03733 | Unannotated protein; Belongs to the GcvT family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.957 |
gcvT_1 | purH | GCA_001642875_03369 | GCA_001642875_04786 | Unannotated protein; Belongs to the GcvT family. | Unannotated protein. | 0.915 |
gcvT_1 | purN | GCA_001642875_03369 | GCA_001642875_04364 | Unannotated protein; Belongs to the GcvT family. | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.915 |
gcvT_1 | purU | GCA_001642875_03369 | GCA_001642875_00205 | Unannotated protein; Belongs to the GcvT family. | Unannotated protein. | 0.916 |
gcvT_2 | arnA | GCA_001642875_00276 | GCA_001642875_04672 | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. | Unannotated protein. | 0.907 |
gcvT_2 | fmt | GCA_001642875_00276 | GCA_001642875_03727 | Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. | Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.907 |