(60 nodes) Cysteine and methionine metabolism network (Procavia capensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPCAP00000011548	annotation not available (415 aa)
	TTC31	Tetratricopeptide repeat domain 31. (519 aa)
	GSS	Glutathione synthetase. (474 aa)
	ENSPCAP00000014124	annotation not available (176 aa)
	BCAT1	Branched chain amino acid transaminase 1. (384 aa)
	SCUBE2	Signal peptide, CUB domain and EGF like domain containing 2. (953 aa)
	TFB2M	Transcription factor B2, mitochondrial. (336 aa)
	MRI1	Methylthioribose-1-phosphate isomerase 1. (365 aa)
	SMS	Spermine synthase. (382 aa)
	TRDMT1	tRNA aspartic acid methyltransferase 1. (391 aa)
	ENSPCAP00000012542	annotation not available (278 aa)
	LDHA	Lactate dehydrogenase A. (331 aa)
	SCUBE1	Signal peptide, CUB domain and EGF like domain containing 1. (954 aa)
	PSAT1	Phosphoserine aminotransferase 1. (369 aa)
	GOT1L1	Glutamic-oxaloacetic transaminase 1 like 1. (419 aa)
	LTO1	LTO1 maturation factor of ABCE1. (136 aa)
	BHMT2	Betaine--homocysteine S-methyltransferase 2. (324 aa)
	AHCYL1	Adenosylhomocysteinase like 1. (531 aa)
	GCLC	Glutamate-cysteine ligase catalytic subunit. (634 aa)
	GOT2	Glutamic-oxaloacetic transaminase 2. (429 aa)
	DNMT1	DNA methyltransferase 1. (1624 aa)
	SRM	Spermidine synthase. (302 aa)
	AHCYL2	Adenosylhomocysteinase like 2. (608 aa)
	SCUBE3	Signal peptide, CUB domain and EGF like domain containing 3. (1010 aa)
	MDH1B	Malate dehydrogenase 1B. (472 aa)
	ENSPCAP00000009463	annotation not available (332 aa)
	HSD17B14	Hydroxysteroid 17-beta dehydrogenase 14. (269 aa)
	BCAT2	Branched chain amino acid transaminase 2. (392 aa)
	ENSPCAP00000009021	annotation not available (497 aa)
	RNF138	Ring finger protein 138. (222 aa)
	ENSPCAP00000007724	annotation not available (499 aa)
	CDO1	Cysteine dioxygenase type 1. (149 aa)
	ENOPH1	Enolase-phosphatase 1. (260 aa)
	ENSPCAP00000007414	annotation not available (242 aa)
	TFB1M	Transcription factor B1, mitochondrial. (300 aa)
	DNMT3A	DNA methyltransferase 3 alpha. (910 aa)
	AMD1	Adenosylmethionine decarboxylase 1. (332 aa)
	TST	Thiosulfate sulfurtransferase. (198 aa)
	AHCY	Adenosylhomocysteinase. (432 aa)
	SDSL	Serine dehydratase like. (325 aa)
	SDS	Serine dehydratase. (326 aa)
	DIMT1	DIMT1 rRNA methyltransferase and ribosome maturation factor. (313 aa)
	ENSPCAP00000004359	annotation not available (291 aa)
	GOT1	Glutamic-oxaloacetic transaminase 1. (413 aa)
	MDH2	Malate dehydrogenase 2. (338 aa)
	MDH1	Malate dehydrogenase 1. (209 aa)
	TSTD1	Thiosulfate sulfurtransferase like domain containing 1. (142 aa)
	ENSPCAP00000003112	annotation not available (452 aa)
	VBP1	VHL binding protein 1. (197 aa)
	IL4I1	Interleukin 4 induced 1. (565 aa)
	CTH	Cystathionine gamma-lyase. (403 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2. (514 aa)
	MTR	5-methyltetrahydrofolate-homocysteine methyltransferase. (1262 aa)
	MAT2B	Methionine adenosyltransferase 2B. (313 aa)
	PHGDH	Phosphoglycerate dehydrogenase. (519 aa)
	MAT1A	Methionine adenosyltransferase 1A. (338 aa)
	MFSD11	Major facilitator superfamily domain containing 11. (449 aa)
	DNMT3B	DNA methyltransferase 3 beta. (852 aa)
	KYAT3	Kynurenine aminotransferase 3. (454 aa)
	ENSPCAP00000000218	annotation not available (228 aa)

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGXT2	BCAT1	ENSPCAP00000002879	ENSPCAP00000013988	Alanine--glyoxylate aminotransferase 2.	Branched chain amino acid transaminase 1.	0.929
AGXT2	BCAT2	ENSPCAP00000002879	ENSPCAP00000009055	Alanine--glyoxylate aminotransferase 2.	Branched chain amino acid transaminase 2.	0.929
AGXT2	CTH	ENSPCAP00000002879	ENSPCAP00000002909	Alanine--glyoxylate aminotransferase 2.	Cystathionine gamma-lyase.	0.928
AGXT2	ENSPCAP00000003112	ENSPCAP00000002879	ENSPCAP00000003112	Alanine--glyoxylate aminotransferase 2.	annotation not available	0.781
AGXT2	ENSPCAP00000004359	ENSPCAP00000002879	ENSPCAP00000004359	Alanine--glyoxylate aminotransferase 2.	annotation not available	0.847
AGXT2	ENSPCAP00000007724	ENSPCAP00000002879	ENSPCAP00000007724	Alanine--glyoxylate aminotransferase 2.	annotation not available	0.568
AGXT2	ENSPCAP00000009463	ENSPCAP00000002879	ENSPCAP00000009463	Alanine--glyoxylate aminotransferase 2.	annotation not available	0.847
AGXT2	ENSPCAP00000011548	ENSPCAP00000002879	ENSPCAP00000011548	Alanine--glyoxylate aminotransferase 2.	annotation not available	0.549
AGXT2	ENSPCAP00000012542	ENSPCAP00000002879	ENSPCAP00000012542	Alanine--glyoxylate aminotransferase 2.	annotation not available	0.803
AGXT2	ENSPCAP00000014124	ENSPCAP00000002879	ENSPCAP00000014124	Alanine--glyoxylate aminotransferase 2.	annotation not available	0.894
AGXT2	HSD17B14	ENSPCAP00000002879	ENSPCAP00000009095	Alanine--glyoxylate aminotransferase 2.	Hydroxysteroid 17-beta dehydrogenase 14.	0.709
AGXT2	KYAT3	ENSPCAP00000002879	ENSPCAP00000000426	Alanine--glyoxylate aminotransferase 2.	Kynurenine aminotransferase 3.	0.549
AGXT2	LDHA	ENSPCAP00000002879	ENSPCAP00000012494	Alanine--glyoxylate aminotransferase 2.	Lactate dehydrogenase A.	0.803
AGXT2	MAT1A	ENSPCAP00000002879	ENSPCAP00000001261	Alanine--glyoxylate aminotransferase 2.	Methionine adenosyltransferase 1A.	0.641
AGXT2	MDH1	ENSPCAP00000002879	ENSPCAP00000003358	Alanine--glyoxylate aminotransferase 2.	Malate dehydrogenase 1.	0.420
AGXT2	MDH1B	ENSPCAP00000002879	ENSPCAP00000009520	Alanine--glyoxylate aminotransferase 2.	Malate dehydrogenase 1B.	0.420
AGXT2	MDH2	ENSPCAP00000002879	ENSPCAP00000003672	Alanine--glyoxylate aminotransferase 2.	Malate dehydrogenase 2.	0.420
AGXT2	PHGDH	ENSPCAP00000002879	ENSPCAP00000001284	Alanine--glyoxylate aminotransferase 2.	Phosphoglycerate dehydrogenase.	0.601
AGXT2	RNF138	ENSPCAP00000002879	ENSPCAP00000008300	Alanine--glyoxylate aminotransferase 2.	Ring finger protein 138.	0.567
AGXT2	SDS	ENSPCAP00000002879	ENSPCAP00000005148	Alanine--glyoxylate aminotransferase 2.	Serine dehydratase.	0.882