(51 nodes) Tryptophan metabolism network (Procavia capensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IDO1	Indoleamine 2,3-dioxygenase 1. (388 aa)
	ACAT2	acetyl-CoA acetyltransferase 2. (333 aa)
	TDO2	Tryptophan 2,3-dioxygenase. (406 aa)
	ENSPCAP00000014541	annotation not available (362 aa)
	GCDH	glutaryl-CoA dehydrogenase. (438 aa)
	ALDH9A1	Aldehyde dehydrogenase 9 family member A1. (457 aa)
	KYNU	Kynureninase. (367 aa)
	ENSPCAP00000012206	annotation not available (641 aa)
	TPH2	Tryptophan hydroxylase 2. (476 aa)
	ENSPCAP00000011548	annotation not available (415 aa)
	HADH	hydroxyacyl-CoA dehydrogenase. (376 aa)
	ENSPCAP00000011235	annotation not available (521 aa)
	ACAD10	acyl-CoA dehydrogenase family member 10. (1058 aa)
	AOC1	Amine oxidase copper containing 1. (749 aa)
	ACAT1	acetyl-CoA acetyltransferase 1. (313 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1. (543 aa)
	TPH1	Tryptophan hydroxylase 1. (331 aa)
	ALDH3A2	Aldehyde dehydrogenase 3 family member A2. (508 aa)
	DLD	Dihydrolipoamide dehydrogenase. (497 aa)
	ENSPCAP00000008837	annotation not available (210 aa)
	FIGNL1	Fidgetin like 1. (677 aa)
	AADAT	Aminoadipate aminotransferase. (425 aa)
	ENSPCAP00000008305	annotation not available (315 aa)
	AOX1	Aldehyde oxidase 1. (1342 aa)
	MAOB	Monoamine oxidase B. (502 aa)
	ENSPCAP00000007370	annotation not available (438 aa)
	ENSPCAP00000015518	annotation not available (178 aa)
	ENSPCAP00000007211	annotation not available (815 aa)
	WDTC1	WD and tetratricopeptide repeats 1. (677 aa)
	GTPBP1	GTP binding protein 1. (667 aa)
	ALDH8A1	Aldehyde dehydrogenase 8 family member A1. (487 aa)
	MAOA	Monoamine oxidase A. (526 aa)
	DLST	Dihydrolipoamide S-succinyltransferase. (410 aa)
	EHHADH	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (723 aa)
	SPAST	Spastin. (473 aa)
	DDC	Dopa decarboxylase. (413 aa)
	CAT	Catalase. (506 aa)
	HADHA	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha. (762 aa)
	IDO2	Indoleamine 2,3-dioxygenase 2. (404 aa)
	FIGN	Fidgetin, microtubule severing factor. (758 aa)
	CARTPT	CART prepropeptide. (115 aa)
	ENSPCAP00000003733	annotation not available (604 aa)
	ALDH16A1	Aldehyde dehydrogenase 16 family member A1. (753 aa)
	ALDH7A1	Aldehyde dehydrogenase 7 family member A1. (431 aa)
	IL4I1	Interleukin 4 induced 1. (565 aa)
	KMO	Kynurenine 3-monooxygenase. (485 aa)
	KYAT3	Kynurenine aminotransferase 3. (454 aa)
	CYP1A1	Cytochrome P450 family 1 subfamily A member 1. (514 aa)
	HAAO	3-hydroxyanthranilate 3,4-dioxygenase. (268 aa)
	CYP1A2	Cytochrome P450 family 1 subfamily A member 2. (383 aa)
	ECHS1	enoyl-CoA hydratase, short chain 1. (290 aa)

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAT	ALDH16A1	ENSPCAP00000008682	ENSPCAP00000003722	Aminoadipate aminotransferase.	Aldehyde dehydrogenase 16 family member A1.	0.527
AADAT	ALDH3A2	ENSPCAP00000008682	ENSPCAP00000009268	Aminoadipate aminotransferase.	Aldehyde dehydrogenase 3 family member A2.	0.533
AADAT	ALDH7A1	ENSPCAP00000008682	ENSPCAP00000003011	Aminoadipate aminotransferase.	Aldehyde dehydrogenase 7 family member A1.	0.908
AADAT	ALDH8A1	ENSPCAP00000008682	ENSPCAP00000006488	Aminoadipate aminotransferase.	Aldehyde dehydrogenase 8 family member A1.	0.586
AADAT	ALDH9A1	ENSPCAP00000008682	ENSPCAP00000014801	Aminoadipate aminotransferase.	Aldehyde dehydrogenase 9 family member A1.	0.527
AADAT	DDC	ENSPCAP00000008682	ENSPCAP00000005545	Aminoadipate aminotransferase.	Dopa decarboxylase.	0.766
AADAT	DLD	ENSPCAP00000008682	ENSPCAP00000008886	Aminoadipate aminotransferase.	Dihydrolipoamide dehydrogenase.	0.892
AADAT	DLST	ENSPCAP00000008682	ENSPCAP00000006078	Aminoadipate aminotransferase.	Dihydrolipoamide S-succinyltransferase.	0.891
AADAT	ECHS1	ENSPCAP00000008682	ENSPCAP00000002041	Aminoadipate aminotransferase.	enoyl-CoA hydratase, short chain 1.	0.562
AADAT	EHHADH	ENSPCAP00000008682	ENSPCAP00000005972	Aminoadipate aminotransferase.	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase.	0.525
AADAT	ENSPCAP00000007211	ENSPCAP00000008682	ENSPCAP00000007211	Aminoadipate aminotransferase.	annotation not available	0.910
AADAT	ENSPCAP00000011235	ENSPCAP00000008682	ENSPCAP00000011235	Aminoadipate aminotransferase.	annotation not available	0.527
AADAT	ENSPCAP00000011548	ENSPCAP00000008682	ENSPCAP00000011548	Aminoadipate aminotransferase.	annotation not available	0.940
AADAT	ENSPCAP00000015518	ENSPCAP00000008682	ENSPCAP00000015518	Aminoadipate aminotransferase.	annotation not available	0.926
AADAT	HAAO	ENSPCAP00000008682	ENSPCAP00000002177	Aminoadipate aminotransferase.	3-hydroxyanthranilate 3,4-dioxygenase.	0.541
AADAT	HADHA	ENSPCAP00000008682	ENSPCAP00000003964	Aminoadipate aminotransferase.	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha.	0.525
AADAT	IDO1	ENSPCAP00000008682	ENSPCAP00000012507	Aminoadipate aminotransferase.	Indoleamine 2,3-dioxygenase 1.	0.755
AADAT	IDO2	ENSPCAP00000008682	ENSPCAP00000003962	Aminoadipate aminotransferase.	Indoleamine 2,3-dioxygenase 2.	0.754
AADAT	KMO	ENSPCAP00000008682	ENSPCAP00000002465	Aminoadipate aminotransferase.	Kynurenine 3-monooxygenase.	0.952
AADAT	KYAT3	ENSPCAP00000008682	ENSPCAP00000000426	Aminoadipate aminotransferase.	Kynurenine aminotransferase 3.	0.940