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| | PPARGC1A | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] (796 aa) |
| | DUSP13 | Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (437 aa) |
| | MTERF1 | Transcription termination factor 1, mitochondrial isoform X1. (401 aa) |
| | A0A286ZJP8_PIG | Uncharacterized protein. (82 aa) |
| | MAF | MAF bZIP transcription factor; Belongs to the bZIP family. (408 aa) |
| | MRPS7 | 28S ribosomal protein S7, mitochondrial. (242 aa) |
| | TNNI1 | Troponin I1, slow skeletal type. (228 aa) |
| | ATP1B4 | Protein ATP1B4; May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit (By similarity). (355 aa) |
| | TCF7 | Transcription factor 7. (484 aa) |
| | IGFN1 | Uncharacterized protein. (1253 aa) |
| | I3LTW5_PIG | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa) |
| | CAPN2 | Calpain-2 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. (726 aa) |
| | ALKBH1 | AlkB homolog 1, histone H2A dioxygenase. (425 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (704 aa) |
| | IGFBP5 | Insulin-like growth factor-binding protein 5; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. (271 aa) |
| | ATP8B2 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1209 aa) |
| | MYBPH | Myosin-binding protein H. (511 aa) |
| | ITGB1BP2 | Integrin beta-1-binding protein 2; May play a role during maturation and/or organization of muscles cells. (342 aa) |
| | ATRAID | Uncharacterized protein. (236 aa) |
| | ATP5ME | ATP synthase subunit e, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (231 aa) |
| | LBX1 | Ladybird homeobox 1. (281 aa) |
| | ASB5 | Ankyrin repeat and SOCS box containing 5. (347 aa) |
| | SLN | Sarcolipin. (31 aa) |
| | LOC100624559 | Phosphodiesterase 4D interacting protein. (2562 aa) |
| | ACTL8 | Actin like 8; Belongs to the actin family. (365 aa) |
| | COLQ | Collagen like tail subunit of asymmetric acetylcholinesterase. (458 aa) |
| | MYH15 | Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1934 aa) |
| | TRIM63 | Uncharacterized protein. (356 aa) |
| | MYH13 | Myosin heavy chain 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa) |
| | SLC2A4 | Solute carrier family 2, facilitated glucose transporter member 4; Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell. (509 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (580 aa) |
| | SGCD | Sarcoglycan delta. (290 aa) |
| | CCNG1 | Cyclin-G1; May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity); Belongs to the cyclin family. Cyclin G subfamily. (161 aa) |
| | TLX3 | T cell leukemia homeobox 3. (338 aa) |
| | PGAM2 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa) |
| | CLCN1 | Chloride channel protein. (986 aa) |
| | NEB | Nebulin. (6665 aa) |
| | CFC1B | EGF-like domain-containing protein. (210 aa) |
| | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] (499 aa) |
| | MYL1 | Uncharacterized protein. (316 aa) |
| | MSTN | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa) |
| | PDLIM3 | PDZ and LIM domain protein 3; May play a role in the organization of actin filament arrays within muscle cells. (365 aa) |
| | MATR3 | Uncharacterized protein. (897 aa) |
| | GMIP | GEM interacting protein. (1090 aa) |
| | MYO9B | Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2194 aa) |
| | TUBB4A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Belongs to the tubulin family. (443 aa) |
| | MYOD1 | Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (319 aa) |
| | LDHC | L-lactate dehydrogenase C chain; Possible role in sperm motility. (332 aa) |
| | ANO5 | Anoctamin. (1156 aa) |
| | CAPN1 | Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. (775 aa) |
| | DKC1 | Uncharacterized protein. (521 aa) |
| | PGK1 | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. (417 aa) |
| | P2RY4 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (365 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (528 aa) |
| | SLC25A26 | Solute carrier family 25 member 26; Belongs to the mitochondrial carrier (TC 2.A.29) family. (284 aa) |
| | MYL3 | Uncharacterized protein. (196 aa) |
| | GPR26 | G-protein coupled receptor 26. (336 aa) |
| | MSS51 | MSS51 mitochondrial translational activator. (460 aa) |
| | P2RX6 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (409 aa) |
| | MYO18B | Myosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2444 aa) |
| | COX18 | Cytochrome c oxidase assembly factor COX18. (337 aa) |
| | F1S9F7_PIG | Uncharacterized protein. (86 aa) |
| | PUS10 | Pseudouridine synthase 10. (531 aa) |
| | NEURL2 | Neuralized E3 ubiquitin protein ligase 2. (285 aa) |
| | FRG1 | FSHD region gene 1. (257 aa) |
| | CIART | Circadian-associated transcriptional repressor isoform a. (453 aa) |
| | CASQ1 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (402 aa) |
| | PDE7A | Phosphodiesterase. (483 aa) |
| | TRIM55 | Tripartite motif containing 55. (540 aa) |
| | SNTB1 | Syntrophin beta 1. (542 aa) |
| | KLHL9 | Kelch like family member 9. (617 aa) |
| | MRPL46 | 39S ribosomal protein L46, mitochondrial. (279 aa) |
| | ACTC1 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (377 aa) |
| | PDIA3 | Protein disulfide-isomerase. (504 aa) |
| | VGLL2 | Vestigial like family member 2. (319 aa) |
| | FHL3 | Four and a half LIM domains 3. (290 aa) |
| | UTP11 | U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (253 aa) |
| | F1STV2_PIG | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa) |
| | F1SUY3_PIG | Uncharacterized protein. (308 aa) |
| | MAMSTR | MEF2 activating motif and SAP domain containing transcriptional regulator. (313 aa) |
| | PTPN21 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1177 aa) |
| | PSMB5 | Uncharacterized protein. (84 aa) |
| | CFL2 | Cofilin-2; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity). (166 aa) |
| | MDFI | MyoD family inhibitor. (246 aa) |
| | TUBB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (230 aa) |
| | ADSL | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (501 aa) |
| | FYCO1 | FYVE and coiled-coil domain containing 1. (1444 aa) |
| | PSME4 | Proteasome activator complex subunit 4. (1843 aa) |
| | MEF2B | Myocyte-specific enhancer factor 2B. (425 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1021 aa) |
| | CDH15 | Cadherin-15 preproprotein; Cadherins are calcium-dependent cell adhesion proteins. (785 aa) |
| | CPT1B | Carnitine O-palmitoyltransferase 1, muscle isoform. (807 aa) |
| | MYOT | Myotilin. (636 aa) |
| | KLHL13 | Kelch like family member 13. (692 aa) |
| | CMTM6 | Uncharacterized protein. (144 aa) |
| | DESI2 | Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. Belongs to the DeSI family. (197 aa) |
| | ENAH | ENAH actin regulator. (782 aa) |
| | PRKAR2A | cAMP-dependent protein kinase type II-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. (389 aa) |
| | TCAP | Uncharacterized protein. (262 aa) |
| | TPM2 | Uncharacterized protein; Belongs to the tropomyosin family. (359 aa) |
| | NLE1 | Notchless homolog 1. (487 aa) |
| | PERM1 | Uncharacterized protein. (894 aa) |
| | ILRUN | N_BRCA1_IG domain-containing protein. (217 aa) |
| | DDIT4 | Uncharacterized protein. (231 aa) |
| | ACTG1 | Actin gamma 1. (381 aa) |
| | CAPN9 | Calpain 9; Belongs to the peptidase C2 family. (723 aa) |
| | SGCA | Sarcoglycan alpha. (387 aa) |
| | FABP3 | Fatty acid-binding protein, heart; FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. (133 aa) |
| | FILIP1 | Filamin-A-interacting protein 1 isoform X1. (1216 aa) |
| | TMEM150A | Transmembrane protein 150A. (271 aa) |
| | TPM3 | Tropomyosin alpha-3 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (303 aa) |
| | SCD | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid ox [...] (425 aa) |
| | CAPN3 | Calpain-3; Calcium-regulated non-lysosomal thiol-protease; Belongs to the peptidase C2 family. (830 aa) |
| | SELENON | Selenoprotein N. (556 aa) |
| | CMSS1 | Cms1 ribosomal small subunit homolog. (279 aa) |
| | GGCT | Uncharacterized protein. (188 aa) |
| | ACYP2 | Acylphosphatase-2; Its physiological role is not yet clear; Belongs to the acylphosphatase family. (188 aa) |
| | RPP38 | Ribonuclease P/MRP subunit p38. (285 aa) |
| | MYLPF | Myosin light chain, phosphorylatable, fast skeletal muscle. (209 aa) |
| | MYH7 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2052 aa) |
| | CKM | Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). (380 aa) |
| | NFU1 | NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 2. (253 aa) |
| | TMX3 | Thioredoxin related transmembrane protein 3. (454 aa) |
| | CLCN4 | Chloride channel protein. (758 aa) |
| | TNNT1 | Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (298 aa) |
| | TRDN | Triadin. (729 aa) |
| | DMD | Dystrophin; Anchors the extracellular matrix to the cytoskeleton via F- actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. (3679 aa) |
| | UTRN | Uncharacterized protein. (3433 aa) |
| | RNF220 | Ring finger protein 220. (565 aa) |
| | ACADM | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). (454 aa) |
| | PDK4 | Protein-serine/threonine kinase. (411 aa) |
| | SLIRP | RRM domain-containing protein. (147 aa) |
| | MYF5 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (253 aa) |
| | MYH3 | Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa) |
| | COMMD6 | Uncharacterized protein. (1300 aa) |
| | MYBPC2 | Myosin binding protein C, fast type. (1290 aa) |
| | SLC19A2 | Uncharacterized protein. (493 aa) |
| | PAX7 | Paired box 7. (521 aa) |
| | SLC41A1 | Solute carrier family 41 member 1 isoform X1. (514 aa) |
| | MYH8 | Myosin-4; Muscle contraction. (1940 aa) |
| | GEMIN2 | Gem nuclear organelle associated protein 2. (372 aa) |
| | NDUFA12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (185 aa) |
| | PCBD2 | Uncharacterized protein. (392 aa) |
| | MYOZ2 | Calsarcin 1. (264 aa) |
| | KMT5B | Lysine methyltransferase 5B. (915 aa) |
| | TACC2 | Uncharacterized protein. (2041 aa) |
| | SRSF1 | Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...] (253 aa) |
| | JSRP1 | Junctional sarcoplasmic reticulum protein 1. (338 aa) |
| | ACTA1 | Actin, alpha skeletal muscle. (465 aa) |
| | KLHL34 | Kelch like family member 34. (651 aa) |
| | FBXO32 | F-box only protein 32; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity). (425 aa) |
| | SMTNL1 | Calponin-homology (CH) domain-containing protein. (182 aa) |
| | A0A287BHF1_PIG | Uncharacterized protein. (90 aa) |
| | TAZ | Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (395 aa) |
| | CA3 | Carbonic anhydrase 3; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. (286 aa) |
| | TXLNA | Taxilin alpha. (643 aa) |
| | A0A287B9U4_PIG | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (104 aa) |
| | LLPH | LLP homolog, long-term synaptic facilitation factor. (127 aa) |
| | PATZ1 | POZ/BTB and AT hook containing zinc finger 1. (581 aa) |
| | MAPK12 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (386 aa) |
| | MAFA | MAF bZIP transcription factor A. (244 aa) |
| | SLC2A4RG | SLC2A4 regulator. (371 aa) |
| | PYGM | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (1369 aa) |
| | CAPN8 | Calpain 8; Belongs to the peptidase C2 family. (727 aa) |
| | CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (588 aa) |
| | MYBPC1 | Myosin binding protein C, slow type. (1233 aa) |
| | INTS11 | Integrator complex subunit 11. (705 aa) |
| | TNNC2 | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. (211 aa) |
| | SHISA4 | Shisa family member 4. (297 aa) |
| | MYH1 | Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity). (1956 aa) |
| | FHL2 | Four and a half LIM domains 2. (333 aa) |
| | ANKRD9 | Uncharacterized protein. (360 aa) |
| | BIN1 | Bridging integrator 1. (588 aa) |
| | PCMTD1 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 isoform 1. (356 aa) |
| | BAG2 | BCL2 associated athanogene 2. (210 aa) |
| | TNNI2 | Uncharacterized protein. (249 aa) |
| | A0A287AUE3_PIG | Uncharacterized protein. (143 aa) |
| | MYOG | Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...] (215 aa) |
| | FLII | FLII actin remodeling protein. (1323 aa) |
| | NGDN | Uncharacterized protein. (328 aa) |
| | SF3B3 | Splicing factor 3B subunit 3. (1217 aa) |
| | RAD23A | RAD23 homolog A, nucleotide excision repair protein. (417 aa) |
| | COX7A1 | Cytochrome c oxidase subunit 7A1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembran [...] (80 aa) |
| | HSPB6 | Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (163 aa) |
| | EYA4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa) |
| | RPLP0 | 60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (322 aa) |
| | ACTBL2 | Actin beta like 2. (385 aa) |
| | A0A287A2B0_PIG | Uncharacterized protein. (78 aa) |
| | MRPL49 | Mitochondrial ribosomal protein L49. (166 aa) |
| | FABP4 | Fatty acid-binding protein, adipocyte; Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). Involved in the regulation of intramuscular fat accretion ; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | LDHA | L-lactate dehydrogenase A chain. (443 aa) |
| | ALPK2 | Alpha kinase 2. (2197 aa) |
| | ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (398 aa) |
| | TXNIP | Thioredoxin-interacting protein; May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) (By similarity). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and co [...] (391 aa) |
| | CUTC | Copper homeostasis protein cutC homolog isoform X1. (273 aa) |
| | SGCZ | Sarcoglycan zeta. (312 aa) |
| | ENO3 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. (476 aa) |
| | HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa) |
| | MYL2 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa) |
| | A0A286ZS34_PIG | Uncharacterized protein. (179 aa) |
| | NEU3 | Neuraminidase 3. (428 aa) |
| | A0A286ZR18_PIG | Uncharacterized protein. (85 aa) |
| | AK1 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (268 aa) |
| | APOC2 | Uncharacterized protein. (198 aa) |
| | CAV3 | Caveolin-3; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. (151 aa) |
