STRINGSTRING
PSMB5 PSMB5 SERPINA12 SERPINA12 PPP6R1 PPP6R1 PADI3 PADI3 GJA1 GJA1 CA12 CA12 TYRP1 TYRP1 GBA GBA DZANK1 DZANK1 SCAND1 SCAND1 WFDC5 WFDC5 INTS1 INTS1 F1S9F7_PIG F1S9F7_PIG NCAPG NCAPG PAN3 PAN3 DCT DCT BMP1 BMP1 P2RX7 P2RX7 ATAD1 ATAD1 PPARG PPARG SERPINI2 SERPINI2 NDUFB5 NDUFB5 MELTF MELTF TIMP1 TIMP1 PNPLA2 PNPLA2 LOC100737419 LOC100737419 LOC100522849 LOC100522849 LOC100524300 LOC100524300 MYC MYC OAZ1 OAZ1 CASP14 CASP14 NDUFA13 NDUFA13 LOX LOX SYTL2 SYTL2 FMOD FMOD COL1A2 COL1A2 LAMB3 LAMB3 SPATA48 SPATA48 AAMP AAMP CREB3L2 CREB3L2 DROSHA DROSHA NARF NARF SRP68 SRP68 STAT3 STAT3 KRT35 KRT35 KRT32 KRT32 KRT34 KRT34 KRT33A KRT33A F1S0J5_PIG F1S0J5_PIG LOC100523275 LOC100523275 LOC106504189 LOC106504189 F1RZX5_PIG F1RZX5_PIG KRT39 KRT39 KRT27 KRT27 CALCOCO2 CALCOCO2 ALOX15B ALOX15B KRT74 KRT74 DSG4 DSG4 EBNA1BP2 EBNA1BP2 ACTL8 ACTL8 KRTAP24-1 KRTAP24-1 DSG1 DSG1 KRTAP27-1 KRTAP27-1 CLEC4F CLEC4F HRNR HRNR LINS1 LINS1 IL6 IL6 DRAM1 DRAM1 TP73 TP73 I3LQK7_PIG I3LQK7_PIG LOC110260322 LOC110260322 EPDR1 EPDR1 EPS8L1 EPS8L1 SLC30A3 SLC30A3 MC1R MC1R CD1.1 CD1.1 CNFN CNFN LOC100516036 LOC100516036 KRT31 KRT31 EGF EGF TYR TYR RPTN RPTN RIPK2 RIPK2 TGM1 TGM1 IER3 IER3 APOD APOD PADI1 PADI1 BGN BGN AWAT2 AWAT2 EDA EDA S100A1 S100A1 TGFB1 TGFB1 SPNS1 SPNS1 ITGA6 ITGA6 LOC100625858 LOC100625858 VIM VIM CREB3 CREB3 GDF15 GDF15 LOC106507258 LOC106507258 NELFCD NELFCD LOC106508044 LOC106508044 A0A286ZR18_PIG A0A286ZR18_PIG A0A286ZR54_PIG A0A286ZR54_PIG A0A286ZS34_PIG A0A286ZS34_PIG FZD3 FZD3 ASB17 ASB17 SURF1 SURF1 WFIKKN1 WFIKKN1 RAB23 RAB23 YIPF3 YIPF3 DPT DPT GAPDH GAPDH ACTB ACTB SOX10 SOX10 A0A286ZXB7_PIG A0A286ZXB7_PIG FABP4 FABP4 FABP5 FABP5 CFLAR CFLAR ASPRV1 ASPRV1 LGR6 LGR6 GREM1 GREM1 KRT80 KRT80 ACTBL2 ACTBL2 HNRNPH3 HNRNPH3 NPTN NPTN AGPAT3 AGPAT3 PRMT5 PRMT5 ACTG1 ACTG1 A0A287AAC1_PIG A0A287AAC1_PIG COL9A3 COL9A3 MON1A MON1A A0A287AEV6_PIG A0A287AEV6_PIG KRTAP11-1 KRTAP11-1 LOC100626876 LOC100626876 LOC100737030 LOC100737030 CXXC1 CXXC1 THOP1 THOP1 TLL2 TLL2 ETV5 ETV5 INS INS MTIF3 MTIF3 LOC100524130 LOC100524130 HMG20B HMG20B LOC110256008 LOC110256008 LGALS7 LGALS7 KRT8 KRT8 CGGBP1 CGGBP1 SF3B3 SF3B3 DDX6 DDX6 KRT40 KRT40 LBR LBR GJB3 GJB3 LOC100523123 LOC100523123 LOC102164863 LOC102164863 FASTK FASTK IFI6 IFI6 TOM1 TOM1 CYC1 CYC1 TCHH TCHH MXRA7 MXRA7 PSRC1 PSRC1 KRTCAP3 KRTCAP3 DDX11 DDX11 CFAP45 CFAP45 MITF MITF IRF2 IRF2 PSMD8 PSMD8 TLL1 TLL1 GPR137B GPR137B LOC100625168 LOC100625168 LOC102162785 LOC102162785 R3HDM4 R3HDM4 RAB38 RAB38 COL5A2 COL5A2 TMEM106C TMEM106C BIRC7 BIRC7 DGAT2L6 DGAT2L6 A0A287BHF1_PIG A0A287BHF1_PIG LEP LEP KRT14 KRT14 LOC100627836 LOC100627836 TMEM69 TMEM69 ZBTB7B ZBTB7B RAB25 RAB25 AIG1 AIG1 LOC110259249 LOC110259249 SYTL1 SYTL1 RSU1 RSU1 SWAP70 SWAP70 VSIG8 VSIG8 LOC100151870 LOC100151870 OBP2B OBP2B DEF8 DEF8 DSTYK DSTYK SDR16C5 SDR16C5 DCST2 DCST2 SPINK5 SPINK5 CD207 CD207 KRTAP17-1 KRTAP17-1 ARMC6 ARMC6 TP63 TP63 DNAJC7 DNAJC7 PLEKHG5 PLEKHG5 COL6A1 COL6A1 TNS1 TNS1 LOC100523770 LOC100523770 EDN3 EDN3 CPZ CPZ VAV3 VAV3 RAB11FIP5 RAB11FIP5 GDPD1 GDPD1 EDEM2 EDEM2 MFSD12 MFSD12 BUD23 BUD23 LAMTOR4 LAMTOR4 A0A5G2QWB6_PIG A0A5G2QWB6_PIG CDCP1 CDCP1 ENTPD6 ENTPD6 SPRY2 SPRY2 DMKN DMKN DDX56 DDX56 LOC100621844 LOC100621844 IL20 IL20 IL23R IL23R A0A5G2RJ22_PIG A0A5G2RJ22_PIG SPARC SPARC TSTA3 TSTA3 BIRC7-2 BIRC7-2 GGCT GGCT COG4 COG4 BOLL BOLL KLF4 KLF4 CIDEA CIDEA KRT75 KRT75 LOC100523670 LOC100523670 KRT5 KRT5 KRT1 KRT1 HOXC13 HOXC13 COPS7A COPS7A IGF1 IGF1 DCN DCN PSME1 PSME1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMB5Uncharacterized protein. (84 aa)
SERPINA12Serpin family A member 12; Belongs to the serpin family. (414 aa)
PPP6R1Protein phosphatase 6 regulatory subunit 1. (881 aa)
PADI3Peptidyl arginine deiminase 3. (664 aa)
GJA1Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...] (382 aa)
CA12Carbonic anhydrase 12; Belongs to the alpha-carbonic anhydrase family. (372 aa)
TYRP15,6-dihydroxyindole-2-carboxylic acid oxidase. (562 aa)
GBALysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. [...] (536 aa)
DZANK1Double zinc ribbon and ankyrin repeat domains 1. (696 aa)
SCAND1SCAN domain-containing protein 1 isoform 1. (179 aa)
WFDC5WAP four-disulfide core domain 5. (166 aa)
INTS1Integrator complex subunit 1. (2191 aa)
F1S9F7_PIGUncharacterized protein. (86 aa)
NCAPGNon-SMC condensin I complex subunit G. (1034 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (906 aa)
DCTL-dopachrome tautomerase; Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels. (519 aa)
BMP1Metalloendopeptidase. (987 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (528 aa)
SERPINI2Serpin family I member 2; Belongs to the serpin family. (405 aa)
NDUFB5NADH dehydrogenase ubiquinone 1 beta subcomplex subunit 5, mitochondrial isoform 1. (189 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (737 aa)
TIMP1Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). (207 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2 isoform X1. (486 aa)
LOC100737419Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (379 aa)
LOC100522849Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (369 aa)
LOC100524300Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (386 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
OAZ1Uncharacterized protein. (225 aa)
CASP14Caspase 14, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (242 aa)
NDUFA13Uncharacterized protein. (144 aa)
LOXProtein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity); Belongs to the lysyl oxidase family. (419 aa)
SYTL2Synaptotagmin like 2. (906 aa)
FMODFibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity). (376 aa)
COL1A2Fibrillar collagen NC1 domain-containing protein. (1135 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
SPATA48Spermatogenesis associated 48. (440 aa)
AAMPAngio associated migratory cell protein. (388 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
DROSHADrosha ribonuclease III. (1397 aa)
NARFNuclear prelamin A recognition factor; Belongs to the NARF family. (463 aa)
SRP68Signal recognition particle 68. (730 aa)
STAT3Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa)
KRT35Keratin 35; Belongs to the intermediate filament family. (455 aa)
KRT32Keratin 32; Belongs to the intermediate filament family. (387 aa)
KRT34IF rod domain-containing protein; Belongs to the intermediate filament family. (391 aa)
KRT33AIF rod domain-containing protein; Belongs to the intermediate filament family. (403 aa)
F1S0J5_PIGUncharacterized protein. (132 aa)
LOC100523275Uncharacterized protein. (179 aa)
LOC106504189Uncharacterized protein. (126 aa)
F1RZX5_PIGUncharacterized protein. (124 aa)
KRT39Keratin 39; Belongs to the intermediate filament family. (490 aa)
KRT27IF rod domain-containing protein; Belongs to the intermediate filament family. (460 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (445 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (718 aa)
KRT74IF rod domain-containing protein; Belongs to the intermediate filament family. (531 aa)
DSG4Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1042 aa)
EBNA1BP2EBNA1 binding protein 2. (400 aa)
ACTL8Actin like 8; Belongs to the actin family. (365 aa)
KRTAP24-1Keratin associated protein 24-1. (253 aa)
DSG1Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (By similarity). (1045 aa)
KRTAP27-1Keratin associated protein 27-1. (206 aa)
CLEC4FC-type lectin domain family 4 member F. (622 aa)
HRNRUncharacterized protein. (266 aa)
LINS1Lines homolog 1. (764 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
DRAM1DNA-damage regulated autophagy modulator 1. (238 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (640 aa)
I3LQK7_PIGGalectin. (135 aa)
LOC110260322Uncharacterized protein. (1023 aa)
EPDR1Ependymin related 1. (234 aa)
EPS8L1EPS8 like 1. (718 aa)
SLC30A3Uncharacterized protein. (464 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a role in the regulation of eumelanin (black/brown) and phaeomelanin (red/yellow) synthesis; Belongs to the G-protein coupled receptor 1 family. (320 aa)
CD1.1T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. (339 aa)
CNFNCornifelin. (199 aa)
LOC100516036IF rod domain-containing protein; Belongs to the intermediate filament family. (422 aa)
KRT31IF rod domain-containing protein; Belongs to the intermediate filament family. (414 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1194 aa)
TYRTyrosinase. (531 aa)
RPTNEF-hand domain-containing protein. (602 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (533 aa)
TGM1Protein-glutamine gamma-glutamyltransferase K. (826 aa)
IER3Immediate early response 3. (214 aa)
APODApolipoprotein D. (228 aa)
PADI1Peptidyl arginine deiminase 1. (663 aa)
BGNBiglycan; May be involved in collagen fiber assembly. (338 aa)
AWAT2Acyl-CoA wax alcohol acyltransferase 2. (329 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (389 aa)
S100A1S100 calcium binding protein A1; Belongs to the S-100 family. (181 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
SPNS1MFS domain-containing protein. (476 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1072 aa)
LOC100625858Uncharacterized protein. (173 aa)
VIMVimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (469 aa)
CREB3cAMP responsive element binding protein 3. (373 aa)
GDF15Growth differentiation factor 15. (308 aa)
LOC106507258IF rod domain-containing protein; Belongs to the intermediate filament family. (483 aa)
NELFCDNegative elongation factor D; Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity). The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity). (657 aa)
LOC106508044Uncharacterized protein. (157 aa)
A0A286ZR18_PIGUncharacterized protein. (85 aa)
A0A286ZR54_PIGUncharacterized protein. (66 aa)
A0A286ZS34_PIGUncharacterized protein. (179 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ASB17Ankyrin repeat and SOCS box containing 17. (295 aa)
SURF1SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (300 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
RAB23RAB23, member RAS oncogene family. (206 aa)
YIPF3Protein YIPF. (335 aa)
DPTDermatopontin; Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation (By similarity). Accelerates collagen fibril formation, and stabilizes collagen fibrils against low- temperature dissociation. (201 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (398 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
SOX10Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity). (542 aa)
A0A286ZXB7_PIGMHC_I-like_Ag-recog domain-containing protein. (326 aa)
FABP4Fatty acid-binding protein, adipocyte; Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). Involved in the regulation of intramuscular fat accretion ; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
FABP5FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (235 aa)
CFLARCASP8 and FADD-like apoptosis regulator isoform 1; Belongs to the peptidase C14A family. (509 aa)
ASPRV1Aspartic peptidase retroviral like 1. (300 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (967 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (240 aa)
KRT80Keratin, type II cytoskeletal 80 isoform K80; Belongs to the intermediate filament family. (452 aa)
ACTBL2Actin beta like 2. (385 aa)
HNRNPH3Heterogeneous nuclear ribonucleoprotein H3. (346 aa)
NPTNNeuroplastin. (412 aa)
AGPAT31-acylglycerol-3-phosphate O-acyltransferase 3. (396 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (670 aa)
ACTG1Actin gamma 1. (381 aa)
A0A287AAC1_PIGUncharacterized protein. (85 aa)
COL9A3Collagen type IX alpha 3 chain. (684 aa)
MON1AUncharacterized protein. (610 aa)
A0A287AEV6_PIGUncharacterized protein. (213 aa)
KRTAP11-1Keratin associated protein 11-1. (157 aa)
LOC100626876Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
LOC100737030IF rod domain-containing protein; Belongs to the intermediate filament family. (452 aa)
CXXC1CXXC finger protein 1. (665 aa)
THOP1Thimet oligopeptidase; Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation; Belongs to the peptidase M3 family. (737 aa)
TLL2Metalloendopeptidase. (1020 aa)
ETV5ETS variant 5. (629 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
MTIF3Mitochondrial translational initiation factor 3. (311 aa)
LOC100524130Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (375 aa)
HMG20BHigh mobility group 20B. (357 aa)
LOC110256008Uncharacterized protein. (100 aa)
LGALS7Galectin. (138 aa)
KRT8Keratin, type II cytoskeletal 8 isoform 2; Belongs to the intermediate filament family. (461 aa)
CGGBP1CGG triplet repeat-binding protein 1. (167 aa)
SF3B3Splicing factor 3B subunit 3. (1217 aa)
DDX6Putative ATP-dependent RNA helicase DDX6 isoform X1; Belongs to the DEAD box helicase family. (483 aa)
KRT40Keratin 40; Belongs to the intermediate filament family. (427 aa)
LBRLamin-B receptor. (626 aa)
GJB3Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (270 aa)
LOC100523123IF rod domain-containing protein; Belongs to the intermediate filament family. (496 aa)
LOC102164863Uncharacterized protein. (175 aa)
FASTKFas activated serine/threonine kinase. (668 aa)
IFI6Interferon alpha inducible protein 6. (171 aa)
TOM1Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (512 aa)
CYC1Cytochrome c1, heme protein, mitochondrial. (326 aa)
TCHHUncharacterized protein. (334 aa)
MXRA7Uncharacterized protein. (194 aa)
PSRC1Proline and serine rich coiled-coil 1. (362 aa)
KRTCAP3Keratinocyte-associated protein 3. (240 aa)
DDX11DEAD/H-box helicase 11. (941 aa)
CFAP45Cilia and flagella associated protein 45. (603 aa)
MITFMicrophthalmia-associated transcription factor isoform 1. (520 aa)
IRF2Interferon regulatory factor 2. (425 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
TLL1Metalloendopeptidase. (1041 aa)
GPR137BG protein-coupled receptor 137B. (415 aa)
LOC100625168Uncharacterized protein. (176 aa)
LOC102162785IF rod domain-containing protein; Belongs to the intermediate filament family. (338 aa)
R3HDM4R3H domain containing 4. (443 aa)
RAB38Ras-related protein Rab-32; Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes. Belongs to the small GTPase superfam [...] (211 aa)
COL5A2Collagen alpha-2(V) chain preproprotein. (1499 aa)
TMEM106CTransmembrane protein 106C. (250 aa)
BIRC7RING-type domain-containing protein. (151 aa)
DGAT2L6Diacylglycerol O-acyltransferase 2 like 6. (337 aa)
A0A287BHF1_PIGUncharacterized protein. (90 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
KRT14Keratin 14; Belongs to the intermediate filament family. (515 aa)
LOC100627836Uncharacterized protein; Belongs to the peptidase C14A family. (470 aa)
TMEM69Transmembrane protein 69. (254 aa)
ZBTB7BZinc finger and BTB domain-containing protein 7B isoform X1. (543 aa)
RAB25RAB25, member RAS oncogene family. (213 aa)
AIG1Androgen induced 1. (315 aa)
LOC110259249Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (369 aa)
SYTL1Synaptotagmin like 1. (602 aa)
RSU1Ras suppressor protein 1. (281 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
VSIG8V-set and immunoglobulin domain containing 8. (414 aa)
LOC100151870Gasdermin C. (517 aa)
OBP2BLipocalin-1; Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket (By similarity). (212 aa)
DEF8Differentially expressed in FDCP 8 homolog. (522 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (1049 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C, member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
DCST2DC-STAMP domain containing 2. (716 aa)
SPINK5Serine peptidase inhibitor, Kazal type 5. (1023 aa)
CD207C-type lectin domain-containing protein. (334 aa)
KRTAP17-1Keratin associated protein 17-1. (116 aa)
ARMC6Armadillo repeat containing 6. (505 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
DNAJC7DnaJ heat shock protein family (Hsp40) member C7. (493 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1078 aa)
COL6A1Collagen type VI alpha 1 chain. (1028 aa)
TNS1Tensin 1. (1861 aa)
LOC100523770Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (375 aa)
EDN3Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. (231 aa)
CPZCarboxypeptidase Z. (666 aa)
VAV3Vav guanine nucleotide exchange factor 3. (874 aa)
RAB11FIP5Uncharacterized protein. (1391 aa)
GDPD1GP-PDE domain-containing protein. (322 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (578 aa)
MFSD12Major facilitator superfamily domain containing 12. (619 aa)
BUD23BUD23 rRNA methyltransferase and ribosome maturation factor. (372 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (100 aa)
A0A5G2QWB6_PIGUncharacterized protein. (979 aa)
CDCP1CUB domain containing protein 1. (838 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (531 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
DMKNDermokine. (531 aa)
DDX56Uncharacterized protein. (554 aa)
LOC100621844IF rod domain-containing protein; Belongs to the intermediate filament family. (488 aa)
IL20Interleukin 20. (175 aa)
IL23RInterleukin 23 receptor. (631 aa)
A0A5G2RJ22_PIGUncharacterized protein. (160 aa)
SPARCSPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity); Belongs to the SPARC family. (331 aa)
TSTA3Tissue specific transplantation antigen P35B. (448 aa)
BIRC7-2Uncharacterized protein. (428 aa)
GGCTUncharacterized protein. (188 aa)
COG4Conserved oligomeric Golgi complex subunit 4 isoform 1. (789 aa)
BOLLBoule homolog, RNA binding protein. (430 aa)
KLF4Kruppel-like factor 4 isoform b. (510 aa)
CIDEACIDE-N domain-containing protein. (376 aa)
KRT75Keratin 75; Belongs to the intermediate filament family. (550 aa)
LOC100523670IF rod domain-containing protein; Belongs to the intermediate filament family. (493 aa)
KRT5Keratin 5; Belongs to the intermediate filament family. (602 aa)
KRT1Keratin 1; Belongs to the intermediate filament family. (624 aa)
HOXC13Homeobox C13. (332 aa)
COPS7ACOP9 signalosome subunit 7A. (296 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (230 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
PSME1Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). (284 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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