(48 nodes) Mixed, incl. Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs., and Negative regulation of Arp2/3 complex-mediated actin nucleation network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCHCR1	Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation. (844 aa)
	ARMC12	Armadillo repeat containing 12. (363 aa)
	TBC1D22B	TBC1 domain family member 22B. (598 aa)
	TBC1D21	TBC1 domain family member 21. (336 aa)
	TBC1D2	TBC1 domain family member 2. (893 aa)
	SUSD1	Sushi domain containing 1. (751 aa)
	TBC1D13	TBC1 domain family member 13. (406 aa)
	FCRL6	Fc receptor-like protein 6 isoform X2. (480 aa)
	TBC1D10B	TBC1 domain family member 10B. (691 aa)
	LOC100513982	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
	TBC1D19	TBC1 domain family member 19. (525 aa)
	WDFY3	WD repeat and FYVE domain containing 3. (3526 aa)
	ECD	Ecdysoneless cell cycle regulator. (689 aa)
	TBC1D5	TBC1 domain family member 5. (828 aa)
	OBP	Odorant-binding protein; This protein is found in nasal epithelium and it binds a wide variety of chemical odorants. (173 aa)
	BCOR	ANK_REP_REGION domain-containing protein. (693 aa)
	RBM3	Uncharacterized protein. (155 aa)
	EVI5	Ecotropic viral integration site 5. (908 aa)
	WDR13	WD repeat domain 13. (587 aa)
	TBC1D23	TBC1 domain family member 23. (735 aa)
	SRPX	Sushi repeat containing protein X-linked. (461 aa)
	MOSPD1	Motile sperm domain containing 1. (215 aa)
	PSORS1C2	Psoriasis susceptibility 1 candidate 2. (135 aa)
	LOC110258247	Rab-GAP TBC domain-containing protein. (310 aa)
	TBC1D9B	TBC1 domain family member 9B. (1268 aa)
	TBC1D25	TBC1 domain family member 25 isoform c. (690 aa)
	TBC1D20	TBC1 domain family member 20 isoform X1. (403 aa)
	GMFB	Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (136 aa)
	CNIH1	Cornichon family AMPA receptor auxiliary protein 1. (160 aa)
	TBC1D15	TBC1 domain family member 15. (674 aa)
	FIS1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
	TBC1D14	Rab-GAP TBC domain-containing protein. (465 aa)
	CNKSR2	Connector enhancer of kinase suppressor of Ras 2. (1050 aa)
	ORMDL3	ORM1-like protein; Negative regulator of sphingolipid synthesis. (173 aa)
	KIF12	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (651 aa)
	ADAM33	ADAM metallopeptidase domain 33. (790 aa)
	C7H6orf226	Uncharacterized protein. (96 aa)
	C6H1orf50	Uncharacterized protein. (588 aa)
	PGAP3	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (368 aa)
	RAB26	RAB26, member RAS oncogene family. (249 aa)
	ADGRL4	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (741 aa)
	TBC1D10C	TBC1 domain family member 10C. (458 aa)
	SGSM2	Small G protein signaling modulator 2. (1341 aa)
	SAPCD1	Suppressor APC domain containing 1. (178 aa)
	ANTXRL	VWFA domain-containing protein. (208 aa)
	TBC1D17	TBC1 domain family member 17. (695 aa)
	GMFG	Glia maturation factor gamma. (195 aa)
	EBPL	EBP like. (237 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM33	CNKSR2	ENSSSCP00000046938	ENSSSCP00000044042	ADAM metallopeptidase domain 33.	Connector enhancer of kinase suppressor of Ras 2.	0.459
ADAM33	ORMDL3	ENSSSCP00000046938	ENSSSCP00000044346	ADAM metallopeptidase domain 33.	ORM1-like protein; Negative regulator of sphingolipid synthesis.	0.702
ADGRL4	ANTXRL	ENSSSCP00000051884	ENSSSCP00000063103	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family.	VWFA domain-containing protein.	0.424
ADGRL4	EBPL	ENSSSCP00000051884	ENSSSCP00000073756	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family.	EBP like.	0.723
ADGRL4	LOC100513982	ENSSSCP00000051884	ENSSSCP00000008845	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.503
ADGRL4	MOSPD1	ENSSSCP00000051884	ENSSSCP00000029160	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family.	Motile sperm domain containing 1.	0.735
ADGRL4	SRPX	ENSSSCP00000051884	ENSSSCP00000028333	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family.	Sushi repeat containing protein X-linked.	0.668
ANTXRL	ADGRL4	ENSSSCP00000063103	ENSSSCP00000051884	VWFA domain-containing protein.	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family.	0.424
ANTXRL	EBPL	ENSSSCP00000063103	ENSSSCP00000073756	VWFA domain-containing protein.	EBP like.	0.422
ANTXRL	MOSPD1	ENSSSCP00000063103	ENSSSCP00000029160	VWFA domain-containing protein.	Motile sperm domain containing 1.	0.779
ARMC12	TBC1D15	ENSSSCP00000001684	ENSSSCP00000041825	Armadillo repeat containing 12.	TBC1 domain family member 15.	0.512
ARMC12	TBC1D21	ENSSSCP00000001684	ENSSSCP00000002094	Armadillo repeat containing 12.	TBC1 domain family member 21.	0.859
BCOR	TBC1D19	ENSSSCP00000013027	ENSSSCP00000009339	ANK_REP_REGION domain-containing protein.	TBC1 domain family member 19.	0.546
C7H6orf226	ECD	ENSSSCP00000047127	ENSSSCP00000010976	Uncharacterized protein.	Ecdysoneless cell cycle regulator.	0.872
C7H6orf226	GMFG	ENSSSCP00000047127	ENSSSCP00000072580	Uncharacterized protein.	Glia maturation factor gamma.	0.613
CCHCR1	EVI5	ENSSSCP00000001472	ENSSSCP00000020009	Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation.	Ecotropic viral integration site 5.	0.457
CCHCR1	FCRL6	ENSSSCP00000001472	ENSSSCP00000006820	Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation.	Fc receptor-like protein 6 isoform X2.	0.770
CCHCR1	KIF12	ENSSSCP00000001472	ENSSSCP00000046355	Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.770
CCHCR1	OBP	ENSSSCP00000001472	ENSSSCP00000012876	Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation.	Odorant-binding protein; This protein is found in nasal epithelium and it binds a wide variety of chemical odorants.	0.531
CCHCR1	ORMDL3	ENSSSCP00000001472	ENSSSCP00000044346	Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation.	ORM1-like protein; Negative regulator of sphingolipid synthesis.	0.403