STRINGSTRING
DHH DHH KIF7 KIF7 GPR161 GPR161 SUFU SUFU GLI2 GLI2 IHH IHH SHH SHH SMO SMO GLI3 GLI3 EVC2 EVC2 SPOP SPOP CDON CDON PTCH1 PTCH1 PTCH2 PTCH2 SPOPL SPOPL EVC EVC HHIP HHIP GLI1 GLI1 BOC BOC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
KIF7Kinesin family member 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1356 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (549 aa)
SUFUSUFU negative regulator of hedgehog signaling. (432 aa)
GLI2GLI family zinc finger 2. (1551 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
GLI3GLI family zinc finger 3. (1586 aa)
EVC2EvC ciliary complex subunit 2. (1299 aa)
SPOPSpeckle type BTB/POZ protein. (374 aa)
CDONCell adhesion associated, oncogene regulated. (1247 aa)
PTCH1Protein patched homolog 1 isoform L. (1452 aa)
PTCH2Patched 2. (1207 aa)
SPOPLSpeckle type BTB/POZ protein like. (392 aa)
EVCEllis-van Creveld syndrome protein isoform 2. (991 aa)
HHIPHedgehog-interacting protein. (700 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1241 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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