STRINGSTRING
ITGA5 ITGA5 LAMA3 LAMA3 THBS1 THBS1 LAMC3 LAMC3 SELE SELE VCAM1 VCAM1 ITGAM ITGAM ITGAL ITGAL DMP1 DMP1 VCL VCL ITGA9 ITGA9 COL4A6 COL4A6 COL1A2 COL1A2 CD36 CD36 LAMB1 LAMB1 LAMC2 LAMC2 LAMB3 LAMB3 FN1 FN1 FLNC FLNC ITGA2 ITGA2 THBS4 THBS4 ITGA3 ITGA3 K7GMK8_PIG K7GMK8_PIG IBSP IBSP ICAM1 ICAM1 TNXB TNXB ITGB1 ITGB1 ITGAV ITGAV ITGA6 ITGA6 ITGAE ITGAE COL3A1 COL3A1 ITGA7 ITGA7 MADCAM1 MADCAM1 LAMA2 LAMA2 LAMC1 LAMC1 LAMA2-2 LAMA2-2 CD34 CD34 ITGA10 ITGA10 TLN1 TLN1 ITGA4 ITGA4 ITGB7 ITGB7 ITGB6 ITGB6 THBS3 THBS3 ITGB2 ITGB2 COL4A5 COL4A5 ITGB8 ITGB8 LAMB2 LAMB2 ITGB5 ITGB5 TLN2 TLN2 ITGA11 ITGA11 TNN TNN FLNB FLNB THBS2 THBS2 COL4A1 COL4A1 PXN PXN CD47 CD47 SELL SELL COL1A1 COL1A1 ITGA1 ITGA1 ITGB4 ITGB4 COL6A6 COL6A6 ITGB3 ITGB3 SELP SELP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1057 aa)
LAMA3Laminin subunit alpha 3. (3345 aa)
THBS1Uncharacterized protein. (1170 aa)
LAMC3Laminin subunit gamma 3. (1575 aa)
SELEE-selectin; Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis (By similarity). Belongs to the selectin/LECAM family. (484 aa)
VCAM1Uncharacterized protein. (537 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1272 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1235 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (531 aa)
VCLVinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family. (1135 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
COL4A6Collagen type IV alpha 6 chain. (1547 aa)
COL1A2Fibrillar collagen NC1 domain-containing protein. (1135 aa)
CD36Platelet glycoprotein 4 isoform X1; Belongs to the CD36 family. (472 aa)
LAMB1Laminin subunit beta 1. (1785 aa)
LAMC2Laminin subunit gamma-2 isoform a. (1191 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
FN1Fibronectin 1. (2462 aa)
FLNCFilamin-C isoform X4. (2720 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1178 aa)
THBS4Thrombospondin 4. (976 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1085 aa)
K7GMK8_PIGSignal transducer CD24 isoform a preproprotein. (78 aa)
IBSPBone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment. (316 aa)
ICAM1Intercellular adhesion molecule 1. (537 aa)
TNXBUncharacterized protein. (4137 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (853 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1052 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1072 aa)
ITGAEIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1168 aa)
COL3A1Collagen alpha-1(III) chain preproprotein. (1471 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1169 aa)
MADCAM1Mucosal addressin cell adhesion molecule 1 isoform a. (390 aa)
LAMA2Uncharacterized protein. (2070 aa)
LAMC1Uncharacterized protein. (1607 aa)
LAMA2-2Uncharacterized protein. (921 aa)
CD34CD34 molecule. (393 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1352 aa)
TLN1Talin 1. (2558 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1055 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (882 aa)
ITGB6Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). (854 aa)
THBS3Thrombospondin-3 isoform 1. (973 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (903 aa)
COL4A5Collagen type IV alpha 5 chain. (1689 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (722 aa)
LAMB2Laminin subunit beta-2. (1881 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
TLN2Talin 2. (2542 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1282 aa)
TNNTenascin N. (1472 aa)
FLNBFilamin B. (2633 aa)
THBS2Thrombospondin 2. (1223 aa)
COL4A1Collagen IV NC1 domain-containing protein. (461 aa)
PXNUncharacterized protein. (1072 aa)
CD47Leukocyte surface antigen CD47; Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. Plays an important role in memory formation and synaptic plasticity in the hippocampus. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeabili [...] (340 aa)
SELLSelectin L. (399 aa)
COL1A1Collagen type I alpha 1 chain. (1477 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1175 aa)
ITGB4Integrin beta. (1814 aa)
COL6A6Collagen type VI alpha 6 chain. (2266 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (835 aa)
SELPUncharacterized protein. (671 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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