(6 nodes) Mixed, incl. Serum albumin, and Thyroid hormone network (Sus scrofa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SERPINA1	Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity). (420 aa)
	AFP	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. (610 aa)
	RBP4	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family. (238 aa)
	GC	GC vitamin D binding protein. (476 aa)
	ORM1	Lipocln_cytosolic_FA-bd_dom domain-containing protein. (212 aa)
	TTR	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Belongs to the transthyretin family. (234 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFP	GC	ENSSSCP00000009550	ENSSSCP00000043366	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	GC vitamin D binding protein.	0.621
AFP	ORM1	ENSSSCP00000009550	ENSSSCP00000070617	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	0.827
AFP	RBP4	ENSSSCP00000009550	ENSSSCP00000038691	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	0.429
AFP	SERPINA1	ENSSSCP00000009550	ENSSSCP00000002681	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity).	0.874
AFP	TTR	ENSSSCP00000009550	ENSSSCP00000072347	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Belongs to the transthyretin family.	0.710
GC	AFP	ENSSSCP00000043366	ENSSSCP00000009550	GC vitamin D binding protein.	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	0.621
GC	ORM1	ENSSSCP00000043366	ENSSSCP00000070617	GC vitamin D binding protein.	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	0.753
GC	RBP4	ENSSSCP00000043366	ENSSSCP00000038691	GC vitamin D binding protein.	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	0.792
GC	SERPINA1	ENSSSCP00000043366	ENSSSCP00000002681	GC vitamin D binding protein.	Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity).	0.744
GC	TTR	ENSSSCP00000043366	ENSSSCP00000072347	GC vitamin D binding protein.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Belongs to the transthyretin family.	0.885
ORM1	AFP	ENSSSCP00000070617	ENSSSCP00000009550	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	0.827
ORM1	GC	ENSSSCP00000070617	ENSSSCP00000043366	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	GC vitamin D binding protein.	0.753
ORM1	RBP4	ENSSSCP00000070617	ENSSSCP00000038691	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	0.425
ORM1	SERPINA1	ENSSSCP00000070617	ENSSSCP00000002681	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity).	0.952
ORM1	TTR	ENSSSCP00000070617	ENSSSCP00000072347	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Belongs to the transthyretin family.	0.817
RBP4	AFP	ENSSSCP00000038691	ENSSSCP00000009550	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	0.429
RBP4	GC	ENSSSCP00000038691	ENSSSCP00000043366	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	GC vitamin D binding protein.	0.792
RBP4	ORM1	ENSSSCP00000038691	ENSSSCP00000070617	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	0.425
RBP4	SERPINA1	ENSSSCP00000038691	ENSSSCP00000002681	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity).	0.445
RBP4	TTR	ENSSSCP00000038691	ENSSSCP00000072347	Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Belongs to the transthyretin family.	0.999