(5 nodes) Mixed, incl. Paired box protein 7 , and Extrinsic component of mitochondrial outer membrane network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZIC1	Zinc finger protein ZIC 1. (447 aa)
	PAX3	Paired box protein Pax-3 isoform PAX3e. (484 aa)
	SOX10	Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity). (542 aa)
	SNAI2	Snail family transcriptional repressor 2. (268 aa)
	FOXD3	Forkhead box D3. (481 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXD3	PAX3	ENSSSCP00000048578	ENSSSCP00000021035	Forkhead box D3.	Paired box protein Pax-3 isoform PAX3e.	0.669
FOXD3	SNAI2	ENSSSCP00000048578	ENSSSCP00000037603	Forkhead box D3.	Snail family transcriptional repressor 2.	0.480
FOXD3	SOX10	ENSSSCP00000048578	ENSSSCP00000035739	Forkhead box D3.	Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).	0.701
FOXD3	ZIC1	ENSSSCP00000048578	ENSSSCP00000012462	Forkhead box D3.	Zinc finger protein ZIC 1.	0.611
PAX3	FOXD3	ENSSSCP00000021035	ENSSSCP00000048578	Paired box protein Pax-3 isoform PAX3e.	Forkhead box D3.	0.669
PAX3	SNAI2	ENSSSCP00000021035	ENSSSCP00000037603	Paired box protein Pax-3 isoform PAX3e.	Snail family transcriptional repressor 2.	0.522
PAX3	SOX10	ENSSSCP00000021035	ENSSSCP00000035739	Paired box protein Pax-3 isoform PAX3e.	Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).	0.937
PAX3	ZIC1	ENSSSCP00000021035	ENSSSCP00000012462	Paired box protein Pax-3 isoform PAX3e.	Zinc finger protein ZIC 1.	0.660
SNAI2	FOXD3	ENSSSCP00000037603	ENSSSCP00000048578	Snail family transcriptional repressor 2.	Forkhead box D3.	0.480
SNAI2	PAX3	ENSSSCP00000037603	ENSSSCP00000021035	Snail family transcriptional repressor 2.	Paired box protein Pax-3 isoform PAX3e.	0.522
SNAI2	SOX10	ENSSSCP00000037603	ENSSSCP00000035739	Snail family transcriptional repressor 2.	Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).	0.648
SOX10	FOXD3	ENSSSCP00000035739	ENSSSCP00000048578	Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).	Forkhead box D3.	0.701
SOX10	PAX3	ENSSSCP00000035739	ENSSSCP00000021035	Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).	Paired box protein Pax-3 isoform PAX3e.	0.937
SOX10	SNAI2	ENSSSCP00000035739	ENSSSCP00000037603	Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).	Snail family transcriptional repressor 2.	0.648
SOX10	ZIC1	ENSSSCP00000035739	ENSSSCP00000012462	Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).	Zinc finger protein ZIC 1.	0.599
ZIC1	FOXD3	ENSSSCP00000012462	ENSSSCP00000048578	Zinc finger protein ZIC 1.	Forkhead box D3.	0.611
ZIC1	PAX3	ENSSSCP00000012462	ENSSSCP00000021035	Zinc finger protein ZIC 1.	Paired box protein Pax-3 isoform PAX3e.	0.660
ZIC1	SOX10	ENSSSCP00000012462	ENSSSCP00000035739	Zinc finger protein ZIC 1.	Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).	0.599