(5 nodes) Beta-catenin phosphorylation cascade network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GSK3A	Protein kinase domain-containing protein. (566 aa)
	AMER1	APC membrane recruitment protein 1. (1108 aa)
	APC	APC_basic domain-containing protein. (2713 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (414 aa)
	AXIN1	Axin 1. (867 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMER1	APC	ENSSSCP00000029629	ENSSSCP00000037698	APC membrane recruitment protein 1.	APC_basic domain-containing protein.	0.971
AMER1	AXIN1	ENSSSCP00000029629	ENSSSCP00000072335	APC membrane recruitment protein 1.	Axin 1.	0.946
AMER1	GSK3B	ENSSSCP00000029629	ENSSSCP00000046229	APC membrane recruitment protein 1.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.850
APC	AMER1	ENSSSCP00000037698	ENSSSCP00000029629	APC_basic domain-containing protein.	APC membrane recruitment protein 1.	0.971
APC	AXIN1	ENSSSCP00000037698	ENSSSCP00000072335	APC_basic domain-containing protein.	Axin 1.	0.996
APC	GSK3A	ENSSSCP00000037698	ENSSSCP00000003288	APC_basic domain-containing protein.	Protein kinase domain-containing protein.	0.628
APC	GSK3B	ENSSSCP00000037698	ENSSSCP00000046229	APC_basic domain-containing protein.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.994
AXIN1	AMER1	ENSSSCP00000072335	ENSSSCP00000029629	Axin 1.	APC membrane recruitment protein 1.	0.946
AXIN1	APC	ENSSSCP00000072335	ENSSSCP00000037698	Axin 1.	APC_basic domain-containing protein.	0.996
AXIN1	GSK3A	ENSSSCP00000072335	ENSSSCP00000003288	Axin 1.	Protein kinase domain-containing protein.	0.863
AXIN1	GSK3B	ENSSSCP00000072335	ENSSSCP00000046229	Axin 1.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.999
GSK3A	APC	ENSSSCP00000003288	ENSSSCP00000037698	Protein kinase domain-containing protein.	APC_basic domain-containing protein.	0.628
GSK3A	AXIN1	ENSSSCP00000003288	ENSSSCP00000072335	Protein kinase domain-containing protein.	Axin 1.	0.863
GSK3A	GSK3B	ENSSSCP00000003288	ENSSSCP00000046229	Protein kinase domain-containing protein.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.902
GSK3B	AMER1	ENSSSCP00000046229	ENSSSCP00000029629	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	APC membrane recruitment protein 1.	0.850
GSK3B	APC	ENSSSCP00000046229	ENSSSCP00000037698	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	APC_basic domain-containing protein.	0.994
GSK3B	AXIN1	ENSSSCP00000046229	ENSSSCP00000072335	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Axin 1.	0.999
GSK3B	GSK3A	ENSSSCP00000046229	ENSSSCP00000003288	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.902