(5 nodes) Mixed, incl. RNA-binding protein Musashi homologue, RNA recognition motif 2, and Spongiotrophoblast differentiation network (Sus scrofa)

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	OLFM4	Olfactomedin 4. (488 aa)
	LRIG1	Leucine rich repeats and immunoglobulin like domains 1. (1112 aa)
	ASCL2	BHLH domain-containing protein. (193 aa)
	MSI1	Musashi RNA binding protein 1. (436 aa)
	HOPX	Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein ref [...] (285 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL2	HOPX	ENSSSCP00000054800	ENSSSCP00000071022	BHLH domain-containing protein.	Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein ref [...]	0.589
ASCL2	LRIG1	ENSSSCP00000054800	ENSSSCP00000012255	BHLH domain-containing protein.	Leucine rich repeats and immunoglobulin like domains 1.	0.829
ASCL2	MSI1	ENSSSCP00000054800	ENSSSCP00000058377	BHLH domain-containing protein.	Musashi RNA binding protein 1.	0.542
ASCL2	OLFM4	ENSSSCP00000054800	ENSSSCP00000010084	BHLH domain-containing protein.	Olfactomedin 4.	0.901
HOPX	ASCL2	ENSSSCP00000071022	ENSSSCP00000054800	Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein ref [...]	BHLH domain-containing protein.	0.589
HOPX	LRIG1	ENSSSCP00000071022	ENSSSCP00000012255	Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein ref [...]	Leucine rich repeats and immunoglobulin like domains 1.	0.692
HOPX	OLFM4	ENSSSCP00000071022	ENSSSCP00000010084	Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein ref [...]	Olfactomedin 4.	0.627
LRIG1	ASCL2	ENSSSCP00000012255	ENSSSCP00000054800	Leucine rich repeats and immunoglobulin like domains 1.	BHLH domain-containing protein.	0.829
LRIG1	HOPX	ENSSSCP00000012255	ENSSSCP00000071022	Leucine rich repeats and immunoglobulin like domains 1.	Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein ref [...]	0.692
LRIG1	MSI1	ENSSSCP00000012255	ENSSSCP00000058377	Leucine rich repeats and immunoglobulin like domains 1.	Musashi RNA binding protein 1.	0.666
LRIG1	OLFM4	ENSSSCP00000012255	ENSSSCP00000010084	Leucine rich repeats and immunoglobulin like domains 1.	Olfactomedin 4.	0.750
MSI1	ASCL2	ENSSSCP00000058377	ENSSSCP00000054800	Musashi RNA binding protein 1.	BHLH domain-containing protein.	0.542
MSI1	LRIG1	ENSSSCP00000058377	ENSSSCP00000012255	Musashi RNA binding protein 1.	Leucine rich repeats and immunoglobulin like domains 1.	0.666
MSI1	OLFM4	ENSSSCP00000058377	ENSSSCP00000010084	Musashi RNA binding protein 1.	Olfactomedin 4.	0.611
OLFM4	ASCL2	ENSSSCP00000010084	ENSSSCP00000054800	Olfactomedin 4.	BHLH domain-containing protein.	0.901
OLFM4	HOPX	ENSSSCP00000010084	ENSSSCP00000071022	Olfactomedin 4.	Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein ref [...]	0.627
OLFM4	LRIG1	ENSSSCP00000010084	ENSSSCP00000012255	Olfactomedin 4.	Leucine rich repeats and immunoglobulin like domains 1.	0.750
OLFM4	MSI1	ENSSSCP00000010084	ENSSSCP00000058377	Olfactomedin 4.	Musashi RNA binding protein 1.	0.611