STRINGSTRING
F1SGR9_PIG F1SGR9_PIG MEP1B MEP1B ASTL ASTL IDE IDE AGTR2 AGTR2 PRCP PRCP ACE ACE MEP1A MEP1A ACE2 ACE2 AGT AGT AGTR1 AGTR1 PREP PREP XPNPEP2 XPNPEP2 THOP1 THOP1 REN REN MME MME DPP4 DPP4 LOC100515049 LOC100515049 MMEL1 MMEL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F1SGR9_PIGPeptidase S1 domain-containing protein. (236 aa)
MEP1BMeprin A subunit. (701 aa)
ASTLMetalloendopeptidase. (392 aa)
IDEInsulin-degrading enzyme isoform X1; Belongs to the peptidase M16 family. (1019 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (362 aa)
PRCPProlylcarboxypeptidase. (511 aa)
ACEAngiotensin-converting enzyme. (1309 aa)
MEP1AMeprin A subunit. (771 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
AGTAngiotensinogen; Belongs to the serpin family. (482 aa)
AGTR1Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (359 aa)
PREPProlyl endopeptidase; Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. (751 aa)
XPNPEP2Xaa-Pro aminopeptidase 2; Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin; Belongs to the peptidase M24B family. (681 aa)
THOP1Thimet oligopeptidase; Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation; Belongs to the peptidase M3 family. (737 aa)
RENRenin preproprotein; Belongs to the peptidase A1 family. (407 aa)
MMENeprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family. (750 aa)
DPP4Dipeptidyl peptidase 4 membrane form; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the mi [...] (833 aa)
LOC100515049Angiotensin-converting enzyme. (771 aa)
MMEL1Membrane metalloendopeptidase like 1. (837 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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