(6 nodes) Lewis blood group biosynthesis network (Sus scrofa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	FUT2	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity). (340 aa)
	B3GALT2	Hexosyltransferase. (422 aa)
	ST3GAL4	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4; Belongs to the glycosyltransferase 29 family. (393 aa)
	ST3GAL3	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family. (374 aa)
	B3GALT5	Hexosyltransferase. (202 aa)
	LOC100513844	Glyco_tran_10_N domain-containing protein. (361 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3GALT2	B3GALT5	ENSSSCP00000011513	ENSSSCP00000058732	Hexosyltransferase.	Hexosyltransferase.	0.900
B3GALT2	FUT2	ENSSSCP00000011513	ENSSSCP00000003406	Hexosyltransferase.	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	0.918
B3GALT2	LOC100513844	ENSSSCP00000011513	ENSSSCP00000062533	Hexosyltransferase.	Glyco_tran_10_N domain-containing protein.	0.921
B3GALT2	ST3GAL3	ENSSSCP00000011513	ENSSSCP00000045432	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.	0.933
B3GALT2	ST3GAL4	ENSSSCP00000011513	ENSSSCP00000016153	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4; Belongs to the glycosyltransferase 29 family.	0.943
B3GALT5	B3GALT2	ENSSSCP00000058732	ENSSSCP00000011513	Hexosyltransferase.	Hexosyltransferase.	0.900
B3GALT5	FUT2	ENSSSCP00000058732	ENSSSCP00000003406	Hexosyltransferase.	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	0.949
B3GALT5	LOC100513844	ENSSSCP00000058732	ENSSSCP00000062533	Hexosyltransferase.	Glyco_tran_10_N domain-containing protein.	0.945
B3GALT5	ST3GAL3	ENSSSCP00000058732	ENSSSCP00000045432	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.	0.941
B3GALT5	ST3GAL4	ENSSSCP00000058732	ENSSSCP00000016153	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4; Belongs to the glycosyltransferase 29 family.	0.919
FUT2	B3GALT2	ENSSSCP00000003406	ENSSSCP00000011513	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	Hexosyltransferase.	0.918
FUT2	B3GALT5	ENSSSCP00000003406	ENSSSCP00000058732	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	Hexosyltransferase.	0.949
FUT2	LOC100513844	ENSSSCP00000003406	ENSSSCP00000062533	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	Glyco_tran_10_N domain-containing protein.	0.986
FUT2	ST3GAL3	ENSSSCP00000003406	ENSSSCP00000045432	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.	0.938
FUT2	ST3GAL4	ENSSSCP00000003406	ENSSSCP00000016153	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4; Belongs to the glycosyltransferase 29 family.	0.931
LOC100513844	B3GALT2	ENSSSCP00000062533	ENSSSCP00000011513	Glyco_tran_10_N domain-containing protein.	Hexosyltransferase.	0.921
LOC100513844	B3GALT5	ENSSSCP00000062533	ENSSSCP00000058732	Glyco_tran_10_N domain-containing protein.	Hexosyltransferase.	0.945
LOC100513844	FUT2	ENSSSCP00000062533	ENSSSCP00000003406	Glyco_tran_10_N domain-containing protein.	Galactoside 2-alpha-L-fucosyltransferase 2; Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (By similarity). Mediates interaction with intestinal microbiota influencing its composition (By similarity). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway (By similarity).	0.986
LOC100513844	ST3GAL3	ENSSSCP00000062533	ENSSSCP00000045432	Glyco_tran_10_N domain-containing protein.	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1; Belongs to the glycosyltransferase 29 family.	0.949
LOC100513844	ST3GAL4	ENSSSCP00000062533	ENSSSCP00000016153	Glyco_tran_10_N domain-containing protein.	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4; Belongs to the glycosyltransferase 29 family.	0.949