STRINGSTRING
DDX23 DDX23 SNRPF SNRPF DHX16 DHX16 CDC5L CDC5L SNRPA SNRPA SNRNP40 SNRNP40 SNRPD1 SNRPD1 PPIH PPIH SF3B4 SF3B4 BUD31 BUD31 CD2BP2 CD2BP2 LUC7L LUC7L SNRNP200 SNRNP200 SF3B6 SF3B6 DHX15 DHX15 TFIP11 TFIP11 SNRPD3 SNRPD3 PPRC1 PPRC1 CCDC12 CCDC12 SF3B2 SF3B2 SART1 SART1 PRPF19 PRPF19 LRRC51 LRRC51 BUD13 BUD13 CWC22 CWC22 PPIL3 PPIL3 CWC27 CWC27 SLU7 SLU7 EFTUD2 EFTUD2 DHX8 DHX8 PRPF8 PRPF8 SNW1 SNW1 SNRNP27 SNRNP27 SNRPN SNRPN GCFC2 GCFC2 PRPF4 PRPF4 SNRPE SNRPE RBMX2 RBMX2 RBM22 RBM22 SNRPG SNRPG SNIP1 SNIP1 PRPF18 PRPF18 CWF19L2 CWF19L2 GPKOW GPKOW SF3B1 SF3B1 AQR AQR PHF5A PHF5A CWC25 CWC25 LSM6 LSM6 A0A286ZN63_PIG A0A286ZN63_PIG A0A286ZN96_PIG A0A286ZN96_PIG WDR53 WDR53 CDC40 CDC40 C19orf54 C19orf54 LOC102162880 LOC102162880 TXNL4A TXNL4A LSM11 LSM11 PRPF40B PRPF40B SNRPB2 SNRPB2 SF3A1 SF3A1 WDR25 WDR25 PPIL1 PPIL1 SNRPB SNRPB SNRNP70 SNRNP70 PRPF31 PRPF31 A0A287ANQ5_PIG A0A287ANQ5_PIG TRNAU1AP TRNAU1AP SF3B3 SF3B3 PRPF6 PRPF6 A0A287AVU1_PIG A0A287AVU1_PIG PPIL2 PPIL2 SYF2 SYF2 A0A287AZB7_PIG A0A287AZB7_PIG A0A287B019_PIG A0A287B019_PIG LSM10 LSM10 LSM2 LSM2 A0A287BAW7_PIG A0A287BAW7_PIG DHX38 DHX38 RNF113A RNF113A PRPF3 PRPF3 RBM25 RBM25 CWC15 CWC15 DHX35 DHX35 LOC102162486 LOC102162486 SNRPA1 SNRPA1 LSM4 LSM4 SNRPC SNRPC DDX46 DDX46 TXNL4B TXNL4B LSM8 LSM8 YJU2 YJU2 SRRM3 SRRM3 SNRPD2 SNRPD2 CRNKL1 CRNKL1 XAB2 XAB2 USP39 USP39 LRMDA LRMDA LSM7 LSM7 SF3A3 SF3A3 LSM5 LSM5 LSM3 LSM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX23DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (820 aa)
SNRPFSm domain-containing protein. (86 aa)
DHX16Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Required for pre-mRNA splicing as component of the spliceosome. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily. (1062 aa)
CDC5LCell division cycle 5-like protein. (802 aa)
SNRPAU1 small nuclear ribonucleoprotein A; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs (By similarity). (281 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (355 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (211 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
BUD31Protein BUD31 homolog isoform X2. (144 aa)
CD2BP2CD2 cytoplasmic tail binding protein 2. (369 aa)
LUC7LLUC7 like. (459 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase isoform X1. (2136 aa)
SF3B6Splicing factor 3B subunit 6. (125 aa)
DHX15Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15. (795 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (836 aa)
SNRPD3Sm domain-containing protein. (281 aa)
PPRC1PPARG related coactivator 1. (1649 aa)
CCDC12Coiled-coil domain containing 12. (216 aa)
SF3B2Splicing factor 3B subunit 2 isoform X1. (895 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (803 aa)
PRPF19Pre-mRNA-processing factor 19. (504 aa)
LRRC51Uncharacterized protein. (193 aa)
BUD13BUD13 homolog. (644 aa)
CWC22CWC22 spliceosome associated protein homolog. (903 aa)
PPIL3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
CWC27Peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 1. (472 aa)
SLU7Pre-mRNA-splicing factor SLU7 isoform X1. (586 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component. (972 aa)
DHX8DEAH-box helicase 8. (1211 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
SNW1SNW domain-containing protein 1 isoform 2. (536 aa)
SNRNP27U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein. (155 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (250 aa)
GCFC2GC-rich sequence DNA-binding factor 2 isoform 1. (784 aa)
PRPF4U4/U6 small nuclear ribonucleoprotein Prp4 isoform X1. (521 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
RBMX2RRM domain-containing protein. (349 aa)
RBM22RNA binding motif protein 22. (559 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
SNIP1Smad nuclear interacting protein 1. (395 aa)
PRPF18SFM domain-containing protein. (342 aa)
CWF19L2CWF19 like cell cycle control factor 2. (856 aa)
GPKOWG-patch domain and KOW motifs. (481 aa)
SF3B1Splicing factor 3B subunit 1 isoform 1. (1304 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
PHF5APHD finger protein 5A. (139 aa)
CWC25Pre-mRNA-splicing factor CWC25 homolog. (425 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (124 aa)
A0A286ZN63_PIGSm domain-containing protein. (68 aa)
A0A286ZN96_PIGRRM domain-containing protein. (90 aa)
WDR53WD repeat-containing protein 53 isoform a. (358 aa)
CDC40Pre-mRNA-processing factor 17. (579 aa)
C19orf54Chromosome 19 open reading frame 54. (366 aa)
LOC102162880Uncharacterized protein. (256 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
LSM11LSM11, U7 small nuclear RNA associated. (357 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (983 aa)
SNRPB2RU2B. (225 aa)
SF3A1Splicing factor 3a subunit 1. (722 aa)
WDR25WD repeat domain 25. (536 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (231 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (436 aa)
PRPF31U4/U6 small nuclear ribonucleoprotein Prp31 isoform X1. (499 aa)
A0A287ANQ5_PIGUncharacterized protein. (412 aa)
TRNAU1APtRNA selenocysteine 1-associated protein 1. (287 aa)
SF3B3Splicing factor 3B subunit 3. (1217 aa)
PRPF6Pre-mRNA processing factor 6. (1150 aa)
A0A287AVU1_PIGUncharacterized protein. (110 aa)
PPIL2Peptidyl-prolyl cis-trans isomerase-like 2 isoform X1. (522 aa)
SYF2SYF2 pre-mRNA splicing factor. (245 aa)
A0A287AZB7_PIGUncharacterized protein. (65 aa)
A0A287B019_PIGRRM domain-containing protein. (135 aa)
LSM10LSM10, U7 small nuclear RNA associated. (121 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
A0A287BAW7_PIGSm domain-containing protein. (117 aa)
DHX38DEAH-box helicase 38. (1325 aa)
RNF113ARing finger protein 113A. (350 aa)
PRPF3U4/U6 small nuclear ribonucleoprotein Prp3 isoform 1. (592 aa)
RBM25RNA binding motif protein 25. (862 aa)
CWC15CWC15 spliceosome associated protein homolog. (254 aa)
DHX35Putative ATP-dependent RNA helicase DHX35 isoform 1. (732 aa)
LOC102162486FMC1-LUC7L2 readthrough. (392 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (269 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (234 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (181 aa)
DDX46DEAD-box helicase 46. (1033 aa)
TXNL4BThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (127 aa)
YJU2YJU2 splicing factor homolog. (377 aa)
SRRM3Serine/arginine repetitive matrix 3. (746 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (140 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (693 aa)
XAB2XPA binding protein 2. (858 aa)
USP39U4/U6.U5 tri-snRNP-associated protein 2 isoform 1. (565 aa)
LRMDALeucine rich melanocyte differentiation associated. (226 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (150 aa)
SF3A3Splicing factor 3a subunit 3. (517 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (92 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (105 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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