node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYP1A1 | CYP2A19 | ENSSSCP00000002085 | ENSSSCP00000003243 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. | 0.929 |
CYP1A1 | EPHX1 | ENSSSCP00000002085 | ENSSSCP00000011571 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | 0.971 |
CYP1A1 | GSTA1 | ENSSSCP00000002085 | ENSSSCP00000002835 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Glutathione S-transferase alpha M14, N-terminally processed; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | 0.948 |
CYP1A1 | GSTO1 | ENSSSCP00000002085 | ENSSSCP00000011305 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.920 |
CYP1A1 | LOC100739163 | ENSSSCP00000002085 | ENSSSCP00000013714 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family. | 0.930 |
CYP2A19 | CYP1A1 | ENSSSCP00000003243 | ENSSSCP00000002085 | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.929 |
CYP2A19 | EPHX1 | ENSSSCP00000003243 | ENSSSCP00000011571 | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | 0.935 |
CYP2A19 | GSTA1 | ENSSSCP00000003243 | ENSSSCP00000002835 | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. | Glutathione S-transferase alpha M14, N-terminally processed; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | 0.956 |
CYP2A19 | GSTO1 | ENSSSCP00000003243 | ENSSSCP00000011305 | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.932 |
CYP2A19 | LOC100739163 | ENSSSCP00000003243 | ENSSSCP00000013714 | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. | Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family. | 0.911 |
EPHX1 | CYP1A1 | ENSSSCP00000011571 | ENSSSCP00000002085 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.971 |
EPHX1 | CYP2A19 | ENSSSCP00000011571 | ENSSSCP00000003243 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. | 0.935 |
EPHX1 | GSTA1 | ENSSSCP00000011571 | ENSSSCP00000002835 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | Glutathione S-transferase alpha M14, N-terminally processed; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | 0.936 |
EPHX1 | GSTO1 | ENSSSCP00000011571 | ENSSSCP00000011305 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.945 |
EPHX1 | LOC100739163 | ENSSSCP00000011571 | ENSSSCP00000013714 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family. | 0.947 |
GSTA1 | CYP1A1 | ENSSSCP00000002835 | ENSSSCP00000002085 | Glutathione S-transferase alpha M14, N-terminally processed; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.948 |
GSTA1 | CYP2A19 | ENSSSCP00000002835 | ENSSSCP00000003243 | Glutathione S-transferase alpha M14, N-terminally processed; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. | 0.956 |
GSTA1 | EPHX1 | ENSSSCP00000002835 | ENSSSCP00000011571 | Glutathione S-transferase alpha M14, N-terminally processed; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | 0.936 |
GSTA1 | GSTO1 | ENSSSCP00000002835 | ENSSSCP00000011305 | Glutathione S-transferase alpha M14, N-terminally processed; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.764 |
GSTA1 | LOC100739163 | ENSSSCP00000002835 | ENSSSCP00000013714 | Glutathione S-transferase alpha M14, N-terminally processed; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. | Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family. | 0.729 |