STRINGSTRING
ADSL ADSL ADCY6 ADCY6 TPMT TPMT LOC100737927 LOC100737927 PDE8A PDE8A FES FES HDDC3 HDDC3 THTPA THTPA PNP PNP AK7 AK7 APRT APRT FOXL1 FOXL1 CES1-2 CES1-2 NPPA NPPA AADACL3 AADACL3 NT5C1A NT5C1A GUCA2B GUCA2B PDE7B PDE7B F1RSY2_PIG F1RSY2_PIG ADAL ADAL CDH19 CDH19 MTAP MTAP UCK1 UCK1 ENTPD8 ENTPD8 PDE7A PDE7A NME7 NME7 ADCY10 ADCY10 NPR1 NPR1 DPYD DPYD NME4 NME4 NME3 NME3 DGUOK DGUOK CEP68 CEP68 XDH XDH DPYSL5 DPYSL5 LOC100516797 LOC100516797 GUCY1A1 GUCY1A1 PPAT PPAT DPYSL2 DPYSL2 TMEM116 TMEM116 UPB1 UPB1 NTPCR NTPCR ENTPD1 ENTPD1 DPYSL4 DPYSL4 NUDT2 NUDT2 NME6 NME6 CAND2 CAND2 UMPS UMPS CLDN17 CLDN17 UPRT UPRT NUDT12 NUDT12 HINT1 HINT1 DPYSL3 DPYSL3 IMPDH1 IMPDH1 ADCY1 ADCY1 ADCY2 ADCY2 NT5M NT5M PDE3A PDE3A RAPGEF3 RAPGEF3 GUCY1A2 GUCY1A2 ADCY5 ADCY5 LOC100525318 LOC100525318 CDA CDA NT5C3A NT5C3A SLC23A1 SLC23A1 ZNF641 ZNF641 NPPC NPPC CRMP1 CRMP1 ENTPD3 ENTPD3 MRVI1 MRVI1 LOC100625149 LOC100625149 GMPS GMPS PDE2A PDE2A NT5C NT5C UPP2 UPP2 GNAL GNAL ATP13A5 ATP13A5 GNAS-2 GNAS-2 ENPP3 ENPP3 GNAS GNAS NT5E NT5E PRKG2 PRKG2 CAMK4 CAMK4 GNG3 GNG3 AK1 AK1 ADCY7 ADCY7 ITGB1BP1 ITGB1BP1 GUK1 GUK1 AK4 AK4 NT5C3B NT5C3B PDE8B PDE8B PDE3B PDE3B DUT DUT UPP1 UPP1 AMPD3 AMPD3 TCERG1L TCERG1L A0A287A4W1_PIG A0A287A4W1_PIG GMPR2 GMPR2 ENPP1 ENPP1 RRM1 RRM1 CES1 CES1 GTPBP1 GTPBP1 HPRT1 HPRT1 PRKG1 PRKG1 DCTD DCTD ENTPD2 ENTPD2 UCK2 UCK2 PAICS PAICS A0A287AI14_PIG A0A287AI14_PIG DPYS DPYS RRM2 RRM2 CANT1 CANT1 PDE11A PDE11A CYB5R4 CYB5R4 NUDT16 NUDT16 NME1 NME1 PM20D1 PM20D1 PDE4D PDE4D GUCY1B1 GUCY1B1 ADCY8 ADCY8 NRSN1 NRSN1 GMPR GMPR AK9 AK9 ADCY9 ADCY9 CTPS1 CTPS1 PDE5A PDE5A PLBD1 PLBD1 NPR2 NPR2 QRICH1 QRICH1 PDE10A PDE10A HRH3 HRH3 ADSS1 ADSS1 NT5C2 NT5C2 OXNAD1 OXNAD1 ADSS2 ADSS2 PRKCD PRKCD TK2 TK2 ITPA ITPA ADA2 ADA2 TK1 TK1 AMPD1 AMPD1 PDE4C PDE4C ADCY4 ADCY4 PBLD PBLD ENTPD5 ENTPD5 ADCY3 ADCY3 AK2 AK2 CYB5R3 CYB5R3 NME2 NME2 CTPS2 CTPS2 A0A5G2QF48_PIG A0A5G2QF48_PIG CMPK1 CMPK1 PDE1A PDE1A AK3 AK3 TPK1 TPK1 DHODH DHODH LOC100519130 LOC100519130 GOLT1B GOLT1B ADK ADK SGSM1 SGSM1 PDE1B PDE1B ADA ADA GDA GDA AK6 AK6 A0A5G2RJL8_PIG A0A5G2RJL8_PIG CMPK2 CMPK2 AK5 AK5 PDE4B PDE4B
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (501 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1164 aa)
TPMTThiopurine S-methyltransferase. (245 aa)
LOC100737927Uncharacterized protein. (1486 aa)
PDE8APhosphodiesterase. (837 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
HDDC3HD domain containing 3. (233 aa)
THTPAThiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP). (230 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (301 aa)
AK7Adenylate kinase 7 isoform 1. (724 aa)
APRTPribosyltran domain-containing protein. (244 aa)
FOXL1Forkhead box protein L1. (338 aa)
CES1-2Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (530 aa)
NPPAAtrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family. (152 aa)
AADACL3Arylacetamide deacetylase like 3. (409 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (365 aa)
GUCA2BGuanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport (By similarity); Belongs to the guanylin family. (113 aa)
PDE7BPhosphodiesterase. (505 aa)
F1RSY2_PIGUncharacterized protein. (293 aa)
ADALAdenosine deaminase-like protein isoform X1. (355 aa)
CDH19Cadherin-19 isoform 1 preproprotein; Cadherins are calcium-dependent cell adhesion proteins. (770 aa)
MTAPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (363 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (277 aa)
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (495 aa)
PDE7APhosphodiesterase. (483 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (377 aa)
ADCY10Adenylate cyclase 10. (1610 aa)
NPR1Guanylate cyclase. (1057 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (973 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
DGUOKDeoxyguanosine kinase, mitochondrial isoform X1. (277 aa)
CEP68Centrosomal protein 68. (698 aa)
XDHXanthine dehydrogenase/oxidase. (1336 aa)
DPYSL5Dihydropyrimidinase-related protein 5 isoform X1. (564 aa)
LOC100516797Uncharacterized protein. (633 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-1 isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (688 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (539 aa)
DPYSL2Dihydropyrimidinase like 2. (635 aa)
TMEM116Transmembrane protein 116 isoform X4. (364 aa)
UPB1Beta-ureidopropionase 1. (393 aa)
NTPCRCancer-related nucleoside-triphosphatase isoform 1. (189 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1 27 kDa subunit; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. (510 aa)
DPYSL4Dihydropyrimidinase like 4. (874 aa)
NUDT2Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. Plays a major role in maintaining homeostasis. (147 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
CAND2Cullin associated and neddylation dissociated 2 (putative). (1236 aa)
UMPSUridine monophosphate synthetase. (486 aa)
CLDN17Claudin-17; Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability. (225 aa)
UPRTUracil phosphoribosyltransferase homolog. (304 aa)
NUDT12Nudix hydrolase 12. (472 aa)
HINT1Histidine triad nucleotide binding protein 1. (126 aa)
DPYSL3Dihydropyrimidinase like 3. (683 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (571 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1136 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (956 aa)
NT5M5',3'-nucleotidase, mitochondrial. (228 aa)
PDE3APhosphodiesterase. (1145 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3 isoform a. (923 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (735 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
LOC100525318Uncharacterized protein. (616 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (313 aa)
SLC23A1Solute carrier family 23 member 1 isoform a. (605 aa)
ZNF641Zinc finger protein 641. (548 aa)
NPPCC-type natriuretic peptide; Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity). (126 aa)
CRMP1Collapsin response mediator protein 1. (784 aa)
ENTPD3Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (500 aa)
MRVI1Murine retrovirus integration site 1 homolog. (938 aa)
LOC100625149Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (676 aa)
GMPSGuanine monophosphate synthase. (699 aa)
PDE2APhosphodiesterase. (1010 aa)
NT5C5', 3'-nucleotidase, cytosolic. (255 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (344 aa)
GNALG protein subunit alpha L. (419 aa)
ATP13A5Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1219 aa)
GNAS-2Guanine nucleotide-binding protein G(s) subunit alpha. (250 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (874 aa)
GNASGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (1045 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (534 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (240 aa)
AK1Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (268 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (270 aa)
GUK1Guanylate kinase; Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP). Involved in the cGMP metabolism in photoreceptors. (242 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa)
PDE8BPhosphodiesterase. (882 aa)
PDE3BPhosphodiesterase. (1117 aa)
DUTDeoxyuridine triphosphatase. (224 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (410 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (802 aa)
TCERG1LTranscription elongation regulator 1 like. (592 aa)
A0A287A4W1_PIGUncharacterized protein. (74 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (352 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (878 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (790 aa)
CES1Liver carboxylesterase; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Active towards triacylglycerides containing short-chain fatty acids from C2 to C6, and 1(3)-monoacylglycerols containing fatty acids from C2 to C12. Inactive on long-chain triacylglycerols and diacylglycerol. Hydrolyzes aromatic and alkyl esters and vitamin A acetate. The hydrolysis rate depends upon the amino acid promoiety and the esterification site of the prodrug. Aromatic promoieties are favored, highest rates are observed with phenylalanyl progdrugs, hydrolysis [...] (564 aa)
GTPBP1GTP binding protein 1. (691 aa)
HPRT1Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). (224 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
DCTDdCMP deaminase. (188 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2 isoform 1; Belongs to the GDA1/CD39 NTPase family. (495 aa)
UCK2Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
PAICSAIRC domain-containing protein. (425 aa)
A0A287AI14_PIGADK_lid domain-containing protein; Belongs to the adenylate kinase family. (207 aa)
DPYSDihydropyrimidinase isoform X1. (519 aa)
RRM2Uncharacterized protein. (439 aa)
CANT1Calcium activated nucleotidase 1. (371 aa)
PDE11APhosphodiesterase. (940 aa)
CYB5R4Cytochrome b5 reductase 4. (546 aa)
NUDT16Nudix hydrolase 16. (211 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
PM20D1N-fatty-acyl-amino acid synthase/hydrolase PM20D1. (489 aa)
PDE4DPhosphodiesterase. (809 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (649 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
NRSN1Neurensin-1 isoform X2. (195 aa)
GMPRIMPDH domain-containing protein. (485 aa)
AK9Uncharacterized protein. (719 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1379 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
PDE5APhosphodiesterase. (884 aa)
PLBD1Heat-stable enterotoxin receptor; Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin (By similarity); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1075 aa)
NPR2Guanylate cyclase. (1094 aa)
QRICH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (1225 aa)
PDE10APhosphodiesterase. (788 aa)
HRH3Histamine receptor H3; Belongs to the G-protein coupled receptor 1 family. (455 aa)
ADSS1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. (452 aa)
NT5C25'-nucleotidase, cytosolic II. (570 aa)
OXNAD1Oxidoreductase NAD binding domain containing 1. (402 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. Belongs to the adenylosuccinate synthetase family. (412 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (723 aa)
TK2Thymidine kinase 2. (318 aa)
ITPAInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (221 aa)
ADA2Adenosine deaminase 2; Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity (By similarity). (509 aa)
TK1Thymidine kinase. (229 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (750 aa)
PDE4CPhosphodiesterase. (729 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1102 aa)
PBLDPhenazine biosynthesis like protein domain containing. (322 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (483 aa)
ADCY3Adenylate cyclase 3. (1320 aa)
AK2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (267 aa)
CYB5R3NADH-cytochrome b5 reductase 3; Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. (300 aa)
NME2Nucleoside diphosphate kinase B; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE I [...] (404 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (620 aa)
A0A5G2QF48_PIGNDK domain-containing protein; Belongs to the NDK family. (121 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (206 aa)
PDE1APhosphodiesterase. (545 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa)
TPK1Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (281 aa)
DHODHDihydroorotate dehydrogenase (quinone). (421 aa)
LOC100519130M20_dimer domain-containing protein. (554 aa)
GOLT1BUncharacterized protein. (138 aa)
ADKAdenosine kinase. (362 aa)
SGSM1Small G protein signaling modulator 1. (1158 aa)
PDE1BPhosphodiesterase. (535 aa)
ADAAdenosine deaminase. (409 aa)
GDAGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (446 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (213 aa)
A0A5G2RJL8_PIGGlutaredoxin domain-containing protein. (104 aa)
CMPK2Cytidine/uridine monophosphate kinase 2. (449 aa)
AK5Adenylate kinase 5; Belongs to the adenylate kinase family. (573 aa)
PDE4BPhosphodiesterase. (736 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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