STRINGSTRING
RUVBL2 RUVBL2 EXOSC3 EXOSC3 EXOSC4 EXOSC4 SIRT1 SIRT1 SETD5 SETD5 MYOD1 MYOD1 CTR9 CTR9 TRIM24 TRIM24 POU4F2 POU4F2 AFF4 AFF4 TRNP1 TRNP1 KMT2E KMT2E POLR2A POLR2A ALKBH1 ALKBH1 PADI2 PADI2 CBX2 CBX2 RBMX RBMX ESR1 ESR1 A0A286ZIN8_PIG A0A286ZIN8_PIG TCF3 TCF3 CTNNB1 CTNNB1 BCAS3 BCAS3 TRIM28 TRIM28 CREB1 CREB1 ICE2 ICE2 SP1 SP1 ICE1 ICE1 RNF2 RNF2 A0A287AVY0_PIG A0A287AVY0_PIG CECR2 CECR2 CBX3 CBX3 HIF1A HIF1A ICE1-2 ICE1-2 PELP1 PELP1 ELL ELL NR1H4 NR1H4 ZC3H8 ZC3H8 UHRF1 UHRF1 PSIP1 PSIP1 TTC37 TTC37 WDR61 WDR61 EXOSC5 EXOSC5 EXOSC10 EXOSC10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (525 aa)
EXOSC3Exosome complex component RRP40 isoform 1. (275 aa)
EXOSC4Exosome complex component RRP41. (245 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform a. (742 aa)
SETD5SET domain containing 5. (1456 aa)
MYOD1Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (319 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1169 aa)
TRIM24Transcription intermediary factor 1-alpha isoform X1. (1050 aa)
POU4F2POU domain protein. (408 aa)
AFF4AF4/FMR2 family member 4 isoform X1. (1164 aa)
TRNP1TMF1 regulated nuclear protein 1. (234 aa)
KMT2EMyeloid/lymphoid or mixed-lineage leukemia 5. (1859 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1942 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (425 aa)
PADI2Peptidyl arginine deiminase 2. (689 aa)
CBX2Chromobox protein homolog 2 isoform X1. (531 aa)
RBMXRNA binding motif protein X-linked. (408 aa)
ESR1Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
A0A286ZIN8_PIGChromo domain-containing protein. (73 aa)
TCF3Transcription factor E2-alpha isoform X12. (642 aa)
CTNNB1Catenin beta 1. (808 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (950 aa)
TRIM28Tripartite motif containing 28. (868 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
ICE2Interactor of little elongation complex ELL subunit 2. (991 aa)
SP1Transcription factor Sp1 isoform a. (786 aa)
ICE1Uncharacterized protein. (232 aa)
RNF2Ring finger protein 2. (368 aa)
A0A287AVY0_PIGChromo domain-containing protein. (67 aa)
CECR2CECR2 histone acetyl-lysine reader. (1291 aa)
CBX3Chromobox protein homolog 3 isoform X1. (183 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (824 aa)
ICE1-2Uncharacterized protein. (1503 aa)
PELP1Proline, glutamate and leucine rich protein 1. (1108 aa)
ELLElongation factor for RNA polymerase II. (657 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (509 aa)
ZC3H8Zinc finger CCCH-type containing 8. (309 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (999 aa)
PSIP1PC4 and SFRS1 interacting protein 1. (530 aa)
TTC37Tetratricopeptide repeat protein 37 isoform X1. (1563 aa)
WDR61WD repeat-containing protein 61 isoform a. (305 aa)
EXOSC5Exosome component 5. (299 aa)
EXOSC10Exosome component 10. (869 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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