STRINGSTRING
GATA3 GATA3 MEGF11 MEGF11 NEUROD4 NEUROD4 MEIS1 MEIS1 NTRK2 NTRK2 TBC1D20 TBC1D20 TFAP2B TFAP2B PBX3 PBX3 RBP4 RBP4 MERTK MERTK SCAPER SCAPER RPL24 RPL24 PRPH2 PRPH2 A0A287A155_PIG A0A287A155_PIG IGFN1 IGFN1 CRYBG3 CRYBG3 CRYGD CRYGD DCX DCX NHS NHS ZEB1 ZEB1 KDR KDR TGFB1 TGFB1 CHRDL1 CHRDL1 RS1 RS1 TGFBR1 TGFBR1 DLG1 DLG1 SMARCA4 SMARCA4 LOC100154892 LOC100154892 YY1 YY1 GJE1 GJE1 PBX2 PBX2 LHX1 LHX1 MAF MAF CRYGC CRYGC TUB TUB CTNNB1 CTNNB1 IMPG2 IMPG2 RPGRIP1L RPGRIP1L LOC100156107 LOC100156107 CALU CALU RARG RARG BAK1 BAK1 KRT12 KRT12 PAX6 PAX6 RD3 RD3 LOC100522220 LOC100522220 SMARCD3 SMARCD3 SOX8 SOX8 AQP5 AQP5 ACVRL1 ACVRL1 GDF11 GDF11 MIP MIP MDM1 MDM1 TULP3 TULP3 KERA KERA RING1 RING1 SRF SRF STRA6 STRA6 NRL NRL RPGRIP1 RPGRIP1 BCL11B BCL11B TMEM231 TMEM231 HSF4 HSF4 ARHGAP35 ARHGAP35 MEIS3 MEIS3 BAX BAX LIM2 LIM2 EPHA2 EPHA2 EPHB2 EPHB2 RPE65 RPE65 FOXE3 FOXE3 CITED2 CITED2 TBC1D32 TBC1D32 FBN1 FBN1 RAX RAX LCTL LCTL NR2E3 NR2E3 BMP4 BMP4 SIX6 SIX6 CRB2 CRB2 LAMC3 LAMC3 COL5A1 COL5A1 MFAP5 MFAP5 FOXL2 FOXL2 ZHX2 ZHX2 MAN2A1 MAN2A1 BIRC7-2 BIRC7-2 SDK1 SDK1 SLC25A25 SLC25A25 SMAD3 SMAD3 GRHL3 GRHL3 ALDH1A2 ALDH1A2 ALDH1A3 ALDH1A3 CRYGS CRYGS RDH10 RDH10 TGFB2 TGFB2 RARA RARA SIX3 SIX3 RDH13 RDH13 MEIS2 MEIS2 LHX2 LHX2 LOC110258874 LOC110258874 C2orf80 C2orf80 C12orf57 C12orf57 PTPRM PTPRM OSR2 OSR2 CALB1 CALB1 CHD7 CHD7 NOTCH2 NOTCH2 HIPK1 HIPK1 GNAT2 GNAT2 BARHL2 BARHL2 JAG1 JAG1 BFSP1 BFSP1 DZANK1 DZANK1 BMP7 BMP7 IFT140 IFT140 RORB RORB BMPR2 BMPR2 COL8A1 COL8A1 ABCB5 ABCB5 GRHL2 GRHL2 RP1 RP1 CRYBG1 CRYBG1 CNTF CNTF TSKU TSKU A0A5G2QU24_PIG A0A5G2QU24_PIG TWSG1 TWSG1 CLCN2 CLCN2 MFSD2A MFSD2A ACVR2B ACVR2B CRYBA1 CRYBA1 PHACTR4 PHACTR4 CRYBB2 CRYBB2 SH3PXD2B SH3PXD2B MFAP2 MFAP2 BBS4 BBS4 MYF5 MYF5 ACHE ACHE FBN2 FBN2 CABP4 CABP4 PFDN5 PFDN5 SLC4A5 SLC4A5 NAGLU NAGLU DLG2 DLG2 CACNA1S CACNA1S A0A5G2QUL4_PIG A0A5G2QUL4_PIG SMOC1 SMOC1 VSTM4 VSTM4 ATF6 ATF6 SCO2 SCO2 AQP1 AQP1 VAX2 VAX2 SOS1 SOS1 CC2D2A CC2D2A MAB21L2 MAB21L2 MAB21L1 MAB21L1 FREM2 FREM2 KDM2B KDM2B FOXN4 FOXN4 CRYBB3 CRYBB3 CRYBB1 CRYBB1 CRYBA4 CRYBA4 NF2 NF2 PDE6C PDE6C PITX3 PITX3 VAX1 VAX1 CRB1 CRB1 KDM5B KDM5B AGTPBP1 AGTPBP1 VHL VHL RHO RHO BFSP2 BFSP2 PRKCI PRKCI SKIL SKIL ACTL6A ACTL6A DSCAM DSCAM LRP5 LRP5 TCIRG1 TCIRG1 RCN1 RCN1 SLC17A6 SLC17A6 USH1C USH1C GRM6 GRM6 PDE6A PDE6A MFRP MFRP GNGT1 GNGT1 RAB3GAP1 RAB3GAP1 SP3 SP3 NEUROD1 NEUROD1 FZD5 FZD5 IHH IHH PRSS56 PRSS56 SHH SHH GLI3 GLI3 FGF10 FGF10 LPCAT1 LPCAT1 SLC6A3 SLC6A3 SOX9 SOX9 STAT3 STAT3 MED1 MED1 NF1 NF1 CTNS CTNS POU4F2 POU4F2 FJX1 FJX1 WT1 WT1 FASLG FASLG RP1L1 RP1L1 TBX2 TBX2 HDAC1 HDAC1 PBX4 PBX4 PXDN PXDN EPHB1 EPHB1 HCN1 HCN1 GPM6A GPM6A VSX1 VSX1 CDON CDON NPHP4 NPHP4 ATOH7 ATOH7 HIPK2 HIPK2 BMPR1B BMPR1B HESX1 HESX1 WDR19 WDR19 PTF1A PTF1A DLL1 DLL1 ARHGEF15 ARHGEF15 RHOJ RHOJ OPN5 OPN5 NR2E1 NR2E1 FGF9 FGF9 JMJD6 JMJD6 FZD4 FZD4 GNAT1 GNAT1 ADAMTS18 ADAMTS18 THRB THRB OPN4 OPN4 TTN TTN AHI1 AHI1 FSCN2 FSCN2 ATF4 ATF4 PRDM1 PRDM1 MFN2 MFN2 SIPA1L3 SIPA1L3 CYP1B1 CYP1B1 BCAR3 BCAR3 B9D1 B9D1 CLN8 CLN8 BMP6 BMP6 BIRC7 BIRC7 TTC8 TTC8 COL5A2 COL5A2 NIPBL NIPBL TSPAN12 TSPAN12 CRYGN CRYGN CRYBG2 CRYBG2 FOXF2 FOXF2 LIMK2 LIMK2 HES5 HES5 FRS2 FRS2 TFAP2A TFAP2A PROX1 PROX1 INHBA INHBA MITF MITF ROM1 ROM1 FZR1 FZR1 HIF1A HIF1A THY1 THY1 PITX2 PITX2 CRYBA2 CRYBA2 PROM1 PROM1 NOTCH1 NOTCH1 PPP1R13L PPP1R13L DRD2 DRD2 SMG9 SMG9 ZNF513 ZNF513 GJA8 GJA8 PDGFRA PDGFRA A0A287AXL0_PIG A0A287AXL0_PIG LAMB2 LAMB2 TH TH PDE6B PDE6B HES1 HES1 PKNOX1 PKNOX1 MYPN MYPN CRYAB CRYAB LOC100524737 LOC100524737 EFEMP1 EFEMP1 LOC100153205 LOC100153205 SIX5 SIX5 A0A287AM16_PIG A0A287AM16_PIG ANGPTL7 ANGPTL7 SLC39A5 SLC39A5 TULP1 TULP1 COL8A2 COL8A2 CRYAA CRYAA CLIC4 CLIC4 ZDHHC16 ZDHHC16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (444 aa)
MEGF11Multiple EGF like domains 11. (1140 aa)
NEUROD4Neurogenic differentiation factor. (331 aa)
MEIS1Homeobox protein Meis1. (465 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
TBC1D20TBC1 domain family member 20 isoform X1. (403 aa)
TFAP2BTranscription factor AP-2 beta. (469 aa)
PBX3PBX homeobox 3. (454 aa)
RBP4Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family. (238 aa)
MERTKMER proto-oncogene, tyrosine kinase. (998 aa)
SCAPERS phase cyclin A-associated protein in the endoplasmic reticulum isoform X1. (1408 aa)
RPL24Ribosomal protein L24. (217 aa)
PRPH2Peripherin 2. (346 aa)
A0A287A155_PIGUncharacterized protein. (58 aa)
IGFN1Uncharacterized protein. (1253 aa)
CRYBG3Crystallin beta-gamma domain containing 3; Belongs to the beta/gamma-crystallin family. (2951 aa)
CRYGDCrystallin gamma D; Belongs to the beta/gamma-crystallin family. (174 aa)
DCXDoublecortin. (365 aa)
NHSNHS actin remodeling regulator. (1621 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1128 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1360 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
CHRDL1Chordin like 1. (526 aa)
RS1Retinoschisin 1. (228 aa)
TGFBR1TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinog [...] (560 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1647 aa)
LOC100154892Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (174 aa)
YY1YY1 transcription factor. (438 aa)
GJE1Gap junction protein epsilon 1. (192 aa)
PBX2Homeobox domain-containing protein. (429 aa)
LHX1LIM homeobox 1. (436 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (408 aa)
CRYGCCrystallin gamma C; Belongs to the beta/gamma-crystallin family. (173 aa)
TUBTubby-like protein; Belongs to the TUB family. (585 aa)
CTNNB1Catenin beta 1. (808 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1244 aa)
RPGRIP1LProtein fantom isoform X1. (1270 aa)
LOC100156107Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (175 aa)
CALUCalumenin. (376 aa)
RARGRetinoic acid receptor gamma. (554 aa)
BAK1Uncharacterized protein. (266 aa)
KRT12Keratin 12; Belongs to the intermediate filament family. (519 aa)
PAX6Paired box 6. (498 aa)
RD3Retinal degeneration 3, GUCY2D regulator. (195 aa)
LOC100522220Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (174 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (548 aa)
SOX8SRY-box transcription factor 8. (460 aa)
AQP5Aquaporin-5; Forms a water-specific channel (By similarity). Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells. Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity); Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
GDF11Growth/differentiation factor 11 preproprotein. (404 aa)
MIPMajor intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
MDM1Mdm1 nuclear protein. (655 aa)
TULP3TUB like protein 3; Belongs to the TUB family. (472 aa)
KERAKeratocan. (351 aa)
RING1Ring finger protein 1. (406 aa)
SRFSerum response factor. (512 aa)
STRA6Stimulated by retinoic acid 6. (666 aa)
NRLNeural retina leucine zipper. (237 aa)
RPGRIP1RPGR interacting protein 1. (939 aa)
BCL11BUncharacterized protein. (888 aa)
TMEM231Transmembrane protein 231. (318 aa)
HSF4Heat shock transcription factor 4. (490 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
MEIS3Meis homeobox 3. (376 aa)
BAXTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (480 aa)
LIM2Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (173 aa)
EPHA2Ephrin type-A receptor 2 isoform 1. (975 aa)
EPHB2EPH receptor B2. (987 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
FOXE3Forkhead box E3. (325 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
TBC1D32Protein broad-minded isoform X1. (1300 aa)
FBN1Fibrillin-1; [Fibrillin-1]: Structural component of the 10-12 nm diameter microfibrils of the extracellular matrix, which conveys both structural and regulatory properties to load-bearing connective tissues. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. In tissues such as the lung, blood vessels and skin, microfibrils form the periphery of the elastic fiber, acting as a scaffold for the deposition of elastin. In addition, microfibrils can occur as elastin-independent networks in tissues such as the ciliary zonule, tendon, cornea and glomerulus [...] (2871 aa)
RAXRetina and anterior neural fold homeobox. (346 aa)
LCTLLactase like; Belongs to the glycosyl hydrolase 1 family. (567 aa)
NR2E3Nuclear receptor subfamily 2 group E member 3. (413 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SIX6Homeobox protein SIX6. (246 aa)
CRB2Crumbs cell polarity complex component 2. (1283 aa)
LAMC3Laminin subunit gamma 3. (1575 aa)
COL5A1Fibrillar collagen NC1 domain-containing protein. (1918 aa)
MFAP5Microfibril associated protein 5. (236 aa)
FOXL2Forkhead box protein L2; Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination (By similarity). Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells (By similarity). Suppresses ESR1- mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Activates SIRT1 transcription under cellular stress conditions (By similarity). Activates [...] (270 aa)
ZHX2Zinc fingers and homeoboxes 2. (827 aa)
MAN2A1Alpha-mannosidase. (1164 aa)
BIRC7-2Uncharacterized protein. (428 aa)
SDK1Sidekick cell adhesion molecule 1. (2141 aa)
SLC25A25Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (533 aa)
SMAD3Mothers against decapentaplegic homolog. (434 aa)
GRHL3Grainyhead like transcription factor 3. (607 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (527 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
CRYGSCrystallin gamma S; Belongs to the beta/gamma-crystallin family. (186 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (443 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
SIX3SIX homeobox 3. (333 aa)
RDH13Retinol dehydrogenase 13 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
MEIS2Meis homeobox 2. (477 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
LOC110258874Fork-head domain-containing protein. (493 aa)
C2orf80Chromosome 2 open reading frame 80. (194 aa)
C12orf57Chromosome 12 open reading frame 57. (126 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1507 aa)
OSR2Odd-skipped related transciption factor 2. (312 aa)
CALB1Calbindin 1. (261 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2863 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa)
HIPK1Homeodomain-interacting protein kinase 1 isoform 1. (1210 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
BARHL2BarH like homeobox 2. (384 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1211 aa)
BFSP1Beaded filament structural protein 1; Belongs to the intermediate filament family. (757 aa)
DZANK1Double zinc ribbon and ankyrin repeat domains 1. (696 aa)
BMP7Bone morphogenetic protein 7. (650 aa)
IFT140Intraflagellar transport 140. (1477 aa)
RORBRAR related orphan receptor B. (548 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1085 aa)
COL8A1Collagen type VIII alpha 1 chain. (759 aa)
ABCB5ATP binding cassette subfamily B member 5. (1257 aa)
GRHL2Grainyhead like transcription factor 2. (626 aa)
RP1RP1 axonemal microtubule associated. (2142 aa)
CRYBG1Beta/gamma crystallin domain-containing protein 1 isoform X1; Belongs to the beta/gamma-crystallin family. (2095 aa)
CNTFCiliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy (By similarity). (619 aa)
TSKUTsukushi, small leucine rich proteoglycan. (357 aa)
A0A5G2QU24_PIGHomeobox domain-containing protein. (317 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (291 aa)
CLCN2Chloride channel protein. (1026 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (541 aa)
ACVR2BActivin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] (565 aa)
CRYBA1Crystallin beta A1; Belongs to the beta/gamma-crystallin family. (217 aa)
PHACTR4Phosphatase and actin regulator. (716 aa)
CRYBB2Crystallin beta B2; Belongs to the beta/gamma-crystallin family. (238 aa)
SH3PXD2BSH3 and PX domains 2B. (958 aa)
MFAP2Microfibril associated protein 2. (276 aa)
BBS4Uncharacterized protein. (826 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (253 aa)
ACHEAcetylcholinesterase (Cartwright blood group); Belongs to the type-B carboxylesterase/lipase family. (765 aa)
FBN2Fibrillin 2. (2910 aa)
CABP4Calcium binding protein 4. (311 aa)
PFDN5Prefoldin subunit 5. (109 aa)
SLC4A5Anion exchange protein. (1111 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (744 aa)
DLG2Discs large MAGUK scaffold protein 2. (1012 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
A0A5G2QUL4_PIGUncharacterized protein. (536 aa)
SMOC1SPARC related modular calcium binding 1. (469 aa)
VSTM4V-set and transmembrane domain containing 4. (382 aa)
ATF6Activating transcription factor 6. (680 aa)
SCO2SCO cytochrome c oxidase assembly protein 2. (264 aa)
AQP1Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. (280 aa)
VAX2Ventral anterior homeobox 2. (288 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1369 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1618 aa)
MAB21L2Protein mab-21-like 2. (359 aa)
MAB21L1Mab-21 like 1. (371 aa)
FREM2FRAS1 related extracellular matrix 2. (3174 aa)
KDM2BLysine demethylase 2B. (1312 aa)
FOXN4Fork-head domain-containing protein. (517 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
CRYBB1Beta-crystallin B1; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family. (249 aa)
CRYBA4Crystallin beta A4; Belongs to the beta/gamma-crystallin family. (221 aa)
NF2Neurofibromin 2. (586 aa)
PDE6CPhosphodiesterase. (859 aa)
PITX3Homeobox protein. (298 aa)
VAX1Ventral anterior homeobox 1. (333 aa)
CRB1Crumbs cell polarity complex component 1. (1464 aa)
KDM5BLysine-specific demethylase 5B isoform 2. (1547 aa)
AGTPBP1ATP/GTP binding protein 1. (1227 aa)
VHLVon Hippel-Lindau disease tumor suppressor isoform 1. (205 aa)
RHORhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity). (348 aa)
BFSP2Beaded filament structural protein 2; Belongs to the intermediate filament family. (415 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (636 aa)
SKILSki-like protein isoform X1. (661 aa)
ACTL6AActin-like protein 6A isoform X1; Belongs to the actin family. (429 aa)
DSCAMDS cell adhesion molecule. (2008 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1614 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (862 aa)
RCN1Reticulocalbin-1. (406 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
USH1CUSH1 protein network component harmonin. (858 aa)
GRM6Glutamate metabotropic receptor 6. (872 aa)
PDE6APhosphodiesterase. (866 aa)
MFRPMembrane frizzled-related protein. (568 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (758 aa)
SP3Sp3 transcription factor. (789 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
PRSS56Serine protease 56; Belongs to the peptidase S1 family. (605 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa)
GLI3GLI family zinc finger 3. (1586 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (534 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (614 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa)
STAT3Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa)
NF1Neurofibromin 1. (2847 aa)
CTNSCystinosin, lysosomal cystine transporter. (373 aa)
POU4F2POU domain protein. (408 aa)
FJX1Four-jointed box kinase 1. (437 aa)
WT1Wilms tumor protein homolog; Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isofor [...] (523 aa)
FASLGTumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3, a decoy receptor tha [...] (282 aa)
RP1L1Uncharacterized protein. (1203 aa)
TBX2T-box 2 protein. (714 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
PBX4PBX homeobox 4. (377 aa)
PXDNPeroxidasin. (1529 aa)
EPHB1Ephrin type-B receptor 1. (984 aa)
HCN1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (885 aa)
GPM6AGlycoprotein M6A. (278 aa)
VSX1Visual system homeobox 1. (364 aa)
CDONCell adhesion associated, oncogene regulated. (1247 aa)
NPHP4Nephrocystin 4. (1466 aa)
ATOH7Atonal bHLH transcription factor 7. (155 aa)
HIPK2Homeodomain interacting protein kinase 2. (1208 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
HESX1HESX homeobox 1. (185 aa)
WDR19WD repeat domain 19. (1342 aa)
PTF1APancreas associated transcription factor 1a. (328 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (729 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (844 aa)
RHOJUncharacterized protein. (213 aa)
OPN5Opsin 5; Belongs to the G-protein coupled receptor 1 family. (378 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
FGF9Fibroblast growth factor 9; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors (By similarity). (228 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (413 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (536 aa)
GNAT1Guanine nucleotide-binding protein G(T) subunit alpha-1 isoform X2. (350 aa)
ADAMTS18ADAM metallopeptidase with thrombospondin type 1 motif 18. (1223 aa)
THRBThyroid hormone receptor beta isoform X2. (476 aa)
OPN4Opsin 4. (488 aa)
TTNUncharacterized protein. (563 aa)
AHI1Abelson helper integration site 1. (1114 aa)
FSCN2Fascin actin-bundling protein 2, retinal. (556 aa)
ATF4Activating transcription factor 4. (329 aa)
PRDM1PR/SET domain 1. (842 aa)
MFN2Mitofusin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
SIPA1L3SPAR_C domain-containing protein. (718 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (860 aa)
B9D1B9 domain containing 1. (204 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (416 aa)
BMP6TGF_BETA_2 domain-containing protein. (537 aa)
BIRC7RING-type domain-containing protein. (151 aa)
TTC8Tetratricopeptide repeat domain 8. (587 aa)
COL5A2Collagen alpha-2(V) chain preproprotein. (1499 aa)
NIPBLNipped-B protein. (2804 aa)
TSPAN12Tetraspanin. (305 aa)
CRYGNGamma-crystallin N isoform X1; Belongs to the beta/gamma-crystallin family. (183 aa)
CRYBG2Crystallin beta-gamma domain containing 2; Belongs to the beta/gamma-crystallin family. (1493 aa)
FOXF2Forkhead box F2. (443 aa)
LIMK2LIM domain kinase 2. (793 aa)
HES5Hes family bHLH transcription factor 5. (226 aa)
FRS2Fibroblast growth factor receptor substrate 2. (550 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
PROX1Prospero homeobox 1. (737 aa)
INHBAInhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. (424 aa)
MITFMicrophthalmia-associated transcription factor isoform 1. (520 aa)
ROM1Retinal outer segment membrane protein 1. (351 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (824 aa)
THY1Thy-1 cell surface antigen. (165 aa)
PITX2Homeobox protein. (326 aa)
CRYBA2Beta-crystallin A2; Belongs to the beta/gamma-crystallin family. (197 aa)
PROM1Prominin 1. (838 aa)
NOTCH1Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (797 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (455 aa)
SMG9SMG9 nonsense mediated mRNA decay factor. (542 aa)
ZNF513Zinc finger protein 513. (572 aa)
GJA8Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (443 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
A0A287AXL0_PIGUncharacterized protein. (502 aa)
LAMB2Laminin subunit beta-2. (1881 aa)
THTyrosine hydroxylase. (596 aa)
PDE6BPhosphodiesterase. (856 aa)
HES1Uncharacterized protein. (280 aa)
PKNOX1PBX/knotted 1 homeobox 1. (435 aa)
MYPNMyopalladin isoform a. (1320 aa)
CRYABAlpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (237 aa)
LOC100524737Uncharacterized protein isoform X1. (232 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (512 aa)
LOC100153205Homeobox domain-containing protein. (375 aa)
SIX5Homeobox protein SIX5. (737 aa)
A0A287AM16_PIGUncharacterized protein. (107 aa)
ANGPTL7Angiopoietin-related protein 7. (344 aa)
SLC39A5Solute carrier family 39 member 5. (554 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (535 aa)
COL8A2Collagen type VIII alpha 2 chain. (707 aa)
CRYAAAlpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. (173 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
ZDHHC16Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (377 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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