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| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa) |
| | LGR5 | Leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1. (907 aa) |
| | ARL3 | ADP-ribosylation factor-like protein 3; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase- activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins to the cilium, including myristoylated NPHP3 and prenylated INPP5E. Targets NPHP3 to the ciliar [...] (306 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (527 aa) |
| | EAF2 | ELL associated factor 2. (273 aa) |
| | HSPB11 | Heat shock protein family B (small) member 11. (157 aa) |
| | TTC8 | Tetratricopeptide repeat domain 8. (587 aa) |
| | BMP6 | TGF_BETA_2 domain-containing protein. (537 aa) |
| | RRM2B | Ribonucleotide reductase regulatory TP53 inducible subunit M2B. (385 aa) |
| | ACVR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (729 aa) |
| | OVOL1 | Ovo like transcriptional repressor 1. (313 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa) |
| | GDF6 | Growth/differentiation factor 6 preproprotein. (459 aa) |
| | PCSK5 | Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1886 aa) |
| | PRDM1 | PR/SET domain 1. (842 aa) |
| | NKX3-1 | Homeobox protein Nkx-3.1 isoform 1. (247 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (221 aa) |
| | AHI1 | Abelson helper integration site 1. (1114 aa) |
| | AMH | Muellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). (577 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa) |
| | JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (413 aa) |
| | AQP1 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. (280 aa) |
| | A0A5G2QUL4_PIG | Uncharacterized protein. (536 aa) |
| | GCNT1 | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase. (428 aa) |
| | DLG2 | Discs large MAGUK scaffold protein 2. (1012 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4383 aa) |
| | NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa) |
| | MTSS1 | MTSS I-BAR domain containing 1. (766 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | A0A5G2QXZ6_PIG | Protein kinase domain-containing protein. (408 aa) |
| | BCL2L11 | Uncharacterized protein. (433 aa) |
| | SIX2 | SIX homeobox 2. (296 aa) |
| | PSAPL1 | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. (518 aa) |
| | CC2D2A | Coiled-coil and C2 domain containing 2A. (1618 aa) |
| | SLIT2 | Slit guidance ligand 2. (1542 aa) |
| | EDNRA | Endothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity). (427 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (523 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (970 aa) |
| | FREM2 | FRAS1 related extracellular matrix 2. (3174 aa) |
| | EDNRB | Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily. (443 aa) |
| | AP1B1 | AP complex subunit beta. (949 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | NID1 | Nidogen 1. (1309 aa) |
| | RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1111 aa) |
| | ACTA2 | Actin alpha 2, smooth muscle. (386 aa) |
| | ITGA8 | Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (398 aa) |
| | EPHB3 | Ephrin type-B receptor 3. (999 aa) |
| | AR | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. (896 aa) |
| | POU3F4 | POU domain protein. (352 aa) |
| | NUP160 | Nucleoporin 160. (1437 aa) |
| | LGR4 | Leucine-rich repeat-containing G-protein coupled receptor 4 isoform 1. (951 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa) |
| | TMEM59L | Transmembrane protein 59-like. (349 aa) |
| | MEF2C | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (483 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa) |
| | AQP11 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa) |
| | KIRREL3 | Kirre like nephrin family adhesion molecule 3. (794 aa) |
| | NPHS2 | NPHS2 stomatin family member, podocin. (378 aa) |
| | CENPF | Centromere protein F. (3035 aa) |
| | HOXD13 | Homeobox protein Hox-D13. (341 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1201 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | COL4A3 | Collagen type IV alpha 3 chain. (1669 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa) |
| | HOXA11 | Homeobox protein Hox-A11. (317 aa) |
| | GLI3 | GLI family zinc finger 3. (1586 aa) |
| | CPLANE1 | Ciliogenesis and planar polarity effector 1. (3098 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | ADAMTS6 | A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X1. (1117 aa) |
| | ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif 16. (1202 aa) |
| | FOXJ1 | Forkhead box J1. (421 aa) |
| | NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (684 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa) |
| | ACE | Angiotensin-converting enzyme. (1309 aa) |
| | HOXB13 | Homeobox B13. (285 aa) |
| | NF1 | Neurofibromin 1. (2847 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (536 aa) |
| | TREX1 | Three prime repair exonuclease 1. (314 aa) |
| | UMOD | Uromodulin. (642 aa) |
| | WT1 | Wilms tumor protein homolog; Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isofor [...] (523 aa) |
| | FEM1B | Protein fem-1 homolog B. (627 aa) |
| | ILK | Integrin linked kinase. (479 aa) |
| | GREB1 | Uncharacterized protein. (1970 aa) |
| | PTPRO | Protein tyrosine phosphatase receptor type O. (1186 aa) |
| | NFIA | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (553 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9. (678 aa) |
| | AQP2 | Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (311 aa) |
| | IFT20 | Intraflagellar transport protein 20 homolog isoform X1. (158 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (729 aa) |
| | HOXC11 | Homeobox C11. (304 aa) |
| | GLIS2 | GLIS family zinc finger 2. (596 aa) |
| | KIF26B | Kinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2109 aa) |
| | TIPARP | TCDD inducible poly(ADP-ribose) polymerase. (657 aa) |
| | POU3F3 | POU domain, class 3, transcription factor 3; Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') (By similarity); Belongs to the POU transcription factor family. Class-3 subfamily. (501 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | HOXA13 | Homeobox A13. (388 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (667 aa) |
| | DCHS2 | Dachsous cadherin-related 2. (3365 aa) |
| | DCHS1 | Dachsous cadherin-related 1. (3294 aa) |
| | PTCH1 | Protein patched homolog 1 isoform L. (1452 aa) |
| | ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1085 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (308 aa) |
| | AMER1 | APC membrane recruitment protein 1. (1108 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (482 aa) |
| | GPC3 | Glypican-3 isoform 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (579 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) |
| | ESR1 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | TGFBR1 | TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinog [...] (560 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa) |
| | PAX2 | Paired box 2. (416 aa) |
| | LHX1 | LIM homeobox 1. (436 aa) |
| | CTNNB1 | Catenin beta 1. (808 aa) |
| | RPGRIP1L | Protein fantom isoform X1. (1270 aa) |
| | RARG | Retinoic acid receptor gamma. (554 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | STAT1 | Signal transducer and activator of transcription 1; Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to [...] (856 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | HEYL | Hairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (328 aa) |
| | SOX8 | SRY-box transcription factor 8. (460 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | SIX4 | Homeobox domain-containing protein. (785 aa) |
| | PRKX | Uncharacterized protein; Belongs to the protein kinase superfamily. (358 aa) |
| | RARA | Retinoic acid receptor alpha isoform X1. (462 aa) |
| | OSR1 | Odd-skipped related transcription factor 1. (267 aa) |
| | NPHS1 | NPHS1 adhesion molecule, nephrin. (1239 aa) |
| | BMP2 | Bone morphogenetic protein 2 preproprotein. (395 aa) |
| | FGF1 | Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with int [...] (182 aa) |
| | BICC1 | BicC family RNA binding protein 1. (1086 aa) |
| | IFT88 | Intraflagellar transport 88. (817 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | GREM1 | Gremlin 1, DAN family BMP antagonist. (240 aa) |
| | GCNT4 | Glucosaminyl (N-acetyl) transferase 4. (632 aa) |
| | KANK2 | KN motif and ankyrin repeat domains 2. (981 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa) |
| | SULF2 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (906 aa) |
| | ASXL1 | ASXL transcriptional regulator 1. (1542 aa) |
| | GZF1 | Uncharacterized protein. (235 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1211 aa) |
| | WDR77 | WD repeat domain 77. (342 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa) |
| | SOX17 | SRY-box transcription factor 17. (407 aa) |
| | PLAG1 | PLAG1 zinc finger. (499 aa) |
| | SULF1 | Sulfatase 1. (1108 aa) |
| | CALB1 | Calbindin 1. (261 aa) |
| | OSR2 | Odd-skipped related transciption factor 2. (312 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) |
| | ANKS6 | Ankyrin repeat and SAM domain-containing protein 6 isoform X3. (874 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa) |
| | SIX1 | Six homeobox 1. (284 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | SMAD6 | Mothers against decapentaplegic homolog. (496 aa) |
| | SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (375 aa) |
| | PYGO1 | Pygopus family PHD finger 1. (419 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog 4; Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for synergistic transcriptional activity in r [...] (552 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (574 aa) |
| | TBX18 | T-box transcription factor TBX18. (612 aa) |
| | TBC1D32 | Protein broad-minded isoform X1. (1300 aa) |
| | GREB1L | GREB1 like retinoic acid receptor coactivator. (1909 aa) |
| | EPHB2 | EPH receptor B2. (987 aa) |
| | BAX | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (480 aa) |
| | SALL1 | Spalt like transcription factor 1. (1326 aa) |
| | IRX3 | Iroquois-class homeodomain protein IRX-3 isoform X2. (502 aa) |
| | ARG2 | Arginase. (354 aa) |
| | STRA6 | Stimulated by retinoic acid 6. (666 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1709 aa) |
| | CTSH | Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. (335 aa) |
| | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4075 aa) |
| | PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa) |
| | BAG6 | Large proline-rich protein BAG6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endo [...] (1163 aa) |
| | LRRK2 | Uncharacterized protein. (2501 aa) |
| | BMP7 | Bone morphogenetic protein 7. (650 aa) |
| | GDF11 | Growth/differentiation factor 11 preproprotein. (404 aa) |
| | TNS2 | Tensin 2. (1350 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | A0A5G2R9S5_PIG | SCHIP-1 domain-containing protein. (485 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (611 aa) |
| | ACVR2B | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] (565 aa) |
| | FRAS1 | Fraser extracellular matrix complex subunit 1. (4013 aa) |
| | MYOCD | Myocardin; Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis) (By similarity). (993 aa) |
| | SPRY1 | Sprouty RTK signaling antagonist 1. (319 aa) |
| | TRAF3IP1 | TRAF3 interacting protein 1. (666 aa) |
| | HNF1B | Hepatocyte nuclear factor 1-beta; Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Binds to the PFC element in the UPA gene. (577 aa) |
| | BMPER | BMP binding endothelial regulator. (699 aa) |
| | PLXND1 | Plexin D1. (1926 aa) |
| | ADAMTS1 | Peptidase M12B domain-containing protein. (963 aa) |
| | C1GALT1 | Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (367 aa) |
| | DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1920 aa) |
| | GCNT3 | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3. (440 aa) |
| | ARID5B | AT-rich interaction domain 5B. (1194 aa) |
| | MYO1E | Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1116 aa) |
| | TFAP2B | Transcription factor AP-2 beta. (469 aa) |
| | BMP10 | Bone morphogenetic protein 10 preproprotein. (423 aa) |
| | HS3ST3A1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (405 aa) |
| | COMMD5 | COMM domain containing 5. (260 aa) |
| | UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (876 aa) |
| | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3. (444 aa) |
| | HS2ST1 | Uncharacterized protein. (356 aa) |
| | NLE1 | Notchless homolog 1. (487 aa) |
| | CTNNBIP1 | Beta-catenin-interacting protein 1. (81 aa) |
| | EMX2 | Empty spiracles homeobox 2. (252 aa) |
| | FOXF1 | Forkhead box protein F1. (423 aa) |
| | FOXA1 | Forkhead box A1. (468 aa) |
| | NUP133 | Nucleoporin 133. (1160 aa) |
| | UPK3A | Uroplakin 3A. (285 aa) |
| | CRLF1 | Cytokine receptor like factor 1. (421 aa) |
| | LRP4 | LDL receptor related protein 4. (1918 aa) |
| | IRX1 | Iroquois homeobox 1. (478 aa) |
| | GDNF | Glial cell line-derived neurotrophic factor isoform 1. (211 aa) |
| | A0A287AIY2_PIG | Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (260 aa) |
| | PECAM1 | Platelet endothelial cell adhesion molecule; Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutr [...] (740 aa) |
| | CDKN1B | p27Kip1. (198 aa) |
| | FOXB1 | Forkhead box protein B1. (325 aa) |
| | A0A287ANG8_PIG | Protein kinase domain-containing protein. (183 aa) |
| | RHOA | Transforming protein RhoA isoform 1. (193 aa) |
| | REN | Renin preproprotein; Belongs to the peptidase A1 family. (407 aa) |
| | HES1 | Uncharacterized protein. (280 aa) |
| | TNC | Tenascin; Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha- V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (By similarity). Belongs to the tenascin family. (2420 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2316 aa) |
| | LAMB2 | Laminin subunit beta-2. (1881 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa) |
| | SEC61A1 | SEC61 translocon alpha 1 subunit. (481 aa) |
| | TSC1 | TSC complex subunit 1. (1166 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (434 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (433 aa) |
| | COL4A4 | Collagen type IV alpha 4 chain. (1691 aa) |
| | LRP2 | Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B (By similarity). In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium (By similarity). Endocytosis of leptin in neuronal cells is required for hyp [...] (4626 aa) |
| | APH1A | Aph-1 homolog A, gamma-secretase subunit. (265 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa) |
| | PROM1 | Prominin 1. (838 aa) |
| | ZBTB14 | Zinc finger and BTB domain-containing protein 14 isoform X1. (449 aa) |
| | KLHL3 | Kelch like family member 3. (601 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | TCF21 | Transcription factor 21. (179 aa) |
| | TFAP2A | Transcription factor AP-2 alpha. (439 aa) |
| | FMN1 | Formin 1. (1195 aa) |
| | EPHA7 | Ephrin type-A receptor 7 isoform 1. (998 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (550 aa) |
| | ID3 | BHLH domain-containing protein. (118 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (226 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (609 aa) |
| | NPHP3 | TPR_REGION domain-containing protein. (1368 aa) |
| | IRX2 | Iroquois-class homeodomain protein IRX-2. (473 aa) |
| | WFS1 | Wolframin ER transmembrane glycoprotein. (889 aa) |
