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ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) | ||||
UPF2 | UPF2 regulator of nonsense mediated mRNA decay. (1270 aa) | ||||
PCK1 | Phosphoenolpyruvate carboxykinase 1. (841 aa) | ||||
RPGRIP1L | Protein fantom isoform X1. (1270 aa) | ||||
CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (513 aa) | ||||
CADM1 | Cell adhesion molecule 1. (473 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (434 aa) | ||||
FGL1 | Fibrinogen like 1. (315 aa) | ||||
CUL3 | Cullin 3; Belongs to the cullin family. (773 aa) | ||||
CEBPG | CCAAT enhancer binding protein gamma. (164 aa) | ||||
PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (673 aa) | ||||
FRZB | Secreted frizzled-related protein 3. (325 aa) | ||||
RHBDD3 | Rhomboid domain-containing protein 3. (428 aa) | ||||
BAAT | Bile acid-CoA:amino acid N-acyltransferase. (407 aa) | ||||
JARID2 | Jumonji and AT-rich interaction domain containing 2. (1245 aa) | ||||
CEBPB | CCAAT/enhancer-binding protein. (346 aa) | ||||
HES1 | Uncharacterized protein. (280 aa) | ||||
NODAL | Nodal growth differentiation factor. (316 aa) | ||||
EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (762 aa) | ||||
XBP1 | BZIP domain-containing protein. (378 aa) | ||||
NOTCH1 | Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa) | ||||
HNF4A | Hepatocyte nuclear factor 4 alpha. (505 aa) | ||||
E2F7 | E2F transcription factor 7. (908 aa) | ||||
PKD1 | Polycystin 1, transient receptor potential channel interacting. (4383 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) | ||||
ARF6 | ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (By similarity). Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (By similarity). Plays an important role in membrane trafficking, during junctional remodeling and epithelial po [...] (175 aa) | ||||
E2F8 | E2F transcription factor 8. (859 aa) | ||||
GLI1 | Zinc finger protein GLI1 isoform X1. (1106 aa) | ||||
NPHP3 | TPR_REGION domain-containing protein. (1368 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
PDX1 | Homeobox domain-containing protein. (284 aa) | ||||
MAN2A1 | Alpha-mannosidase. (1164 aa) | ||||
HLX | H2.0 like homeobox. (556 aa) | ||||
ADA | Adenosine deaminase. (409 aa) | ||||
HNF1B | Hepatocyte nuclear factor 1-beta; Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Binds to the PFC element in the UPA gene. (577 aa) | ||||
ACADM | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). (454 aa) | ||||
PROX1 | Prospero homeobox 1. (737 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
DNAAF1 | Dynein assembly factor 1, axonemal. (650 aa) | ||||
LSR | Lipolysis stimulated lipoprotein receptor. (598 aa) | ||||
GATA6 | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. (592 aa) | ||||
CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) | ||||
LOC100511607 | Uncharacterized protein. (340 aa) | ||||
LOC100512146 | Uncharacterized protein. (358 aa) | ||||
SEC63 | SEC63 homolog, protein translocation regulator. (760 aa) | ||||
ONECUT2 | One cut domain family member. (694 aa) | ||||
ONECUT1 | One cut domain family member. (465 aa) | ||||
ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa) | ||||
NOTCH2 | Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa) | ||||
SULF2 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (906 aa) | ||||
GFER | Sulfhydryl oxidase. (365 aa) | ||||
TGFA | Protransforming growth factor alpha; TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. (160 aa) | ||||
PKD2 | Polycystin 2, transient receptor potential cation channel. (970 aa) | ||||
TBX3 | T-box transcription factor TBX3 isoform 2. (745 aa) | ||||
HNF1A | Hepatocyte nuclear factor 1-alpha isoform 2. (631 aa) | ||||
SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) | ||||
CCDC39 | Coiled-coil domain-containing protein 39. (942 aa) | ||||
ZIC3 | Zic family member 3. (467 aa) | ||||
RELA | Transcription factor p65 isoform 1. (573 aa) | ||||
PRKCSH | Glucosidase 2 subunit beta isoform X1. (537 aa) | ||||
HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa) | ||||
F1SF13_PIG | Cobl domain-containing protein. (406 aa) | ||||
SP3 | Sp3 transcription factor. (789 aa) | ||||
MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1381 aa) | ||||
SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa) | ||||
NF1 | Neurofibromin 1. (2847 aa) | ||||
CCDC40 | Coiled-coil domain containing 40. (986 aa) | ||||
TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (217 aa) | ||||
RB1CC1 | RB1 inducible coiled-coil 1. (1608 aa) | ||||
PCSK9 | Proprotein convertase subtilisin/kexin type 9. (678 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa) |