STRINGSTRING
CBS CBS CSGALNACT1 CSGALNACT1 SMPD3 SMPD3 A0A287AXH2_PIG A0A287AXH2_PIG SCX SCX BMP6 BMP6 ALPL ALPL COL1A1 COL1A1 RUNX2 RUNX2 PHOSPHO1 PHOSPHO1 COL13A1 COL13A1 PHOSPHO2 PHOSPHO2 NAB2 NAB2 BMP4 BMP4 EXT1 EXT1 LOC100517735 LOC100517735 MEF2C MEF2C MMP13 MMP13 IFT80 IFT80 I3L7W9_PIG I3L7W9_PIG MMP14 MMP14 FGF18 FGF18 GNAS GNAS COL2A1 COL2A1 IMPAD1 IMPAD1 MEF2D MEF2D DLX5 DLX5 MMP16 MMP16 PEX7 PEX7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (611 aa)
CSGALNACT1Hexosyltransferase. (525 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
A0A287AXH2_PIGUncharacterized protein. (284 aa)
SCXBasic helix-loop-helix transcription factor scleraxis. (310 aa)
BMP6TGF_BETA_2 domain-containing protein. (537 aa)
ALPLAlkaline phosphatase. (834 aa)
COL1A1Collagen type I alpha 1 chain. (1477 aa)
RUNX2Runt-related transcription factor 2 isoform a. (625 aa)
PHOSPHO1Uncharacterized protein. (465 aa)
COL13A1Collagen type XIII alpha 1 chain. (726 aa)
PHOSPHO2Pyridoxal phosphate phosphatase PHOSPHO2. (241 aa)
NAB2NGFI-A binding protein 2. (525 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
LOC100517735Hexosyltransferase. (384 aa)
MEF2CMyocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (483 aa)
MMP13Matrix metallopeptidase 13. (470 aa)
IFT80Intraflagellar transport 80. (767 aa)
I3L7W9_PIGUncharacterized protein. (373 aa)
MMP14Matrix metalloproteinase-14; Endopeptidase that degrades various components of the extracellular matrix, such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15 in association with pro-MMP2. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which i [...] (606 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
GNASGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (1045 aa)
COL2A1Collagen type II alpha 1 chain. (1486 aa)
IMPAD1Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; Exhibits 3'-nucleotidase activity toward adenosine 3',5'- bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, [...] (359 aa)
MEF2DMyocyte enhancer factor 2D. (531 aa)
DLX5Homeobox protein DLX-5. (290 aa)
MMP16Matrix metalloproteinase-16. (607 aa)
PEX7Peroxisomal biogenesis factor 7. (308 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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