STRINGSTRING
GDF11 GDF11 CDH2 CDH2 BMP4 BMP4 GPAT4 GPAT4 SLC9A4 SLC9A4 SIDT2 SIDT2 FZD5 FZD5 SMO SMO FASN FASN DLL1 DLL1 CDK6 CDK6 RARG RARG PAX6 PAX6 RARA RARA PDPK1 PDPK1 BMP5 BMP5 WNT5A WNT5A SPDEF SPDEF HIF1A HIF1A BHLHA15 BHLHA15 NKX2-2 NKX2-2 BMP6 BMP6 HNF4A HNF4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GDF11Growth/differentiation factor 11 preproprotein. (404 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
GPAT4PlsC domain-containing protein. (457 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
SIDT2SID1 transmembrane family member 2. (860 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
FASNUncharacterized protein. (1430 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (729 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
RARGRetinoic acid receptor gamma. (554 aa)
PAX6Paired box 6. (498 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (668 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (363 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (824 aa)
BHLHA15Basic helix-loop-helix family member a15. (234 aa)
NKX2-2Homeobox protein Nkx-2.2. (273 aa)
BMP6TGF_BETA_2 domain-containing protein. (537 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (505 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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